8GI6
 
 | | Crystal structure of RhoA mutant L69R complexed with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | 著者 | Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J. | | 登録日 | 2023-03-13 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Ras-like GTPases mutant structures
To be published
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8GI3
 | | Crystal structure of RhoA mutant L69P complexed with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA | | 著者 | Chen, X, Qian, X, Chandravanshi, M, Lowy, D.R, Walters, K.J. | | 登録日 | 2023-03-13 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Ras-like GTPases mutants structure
To be published
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7F8L
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8J9M
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8J9L
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8JAI
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8GRD
 | | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | | 著者 | Chen, X, Sun, P, Ding, J. | | 登録日 | 2022-09-01 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
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6K9C
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6K9E
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6LRB
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5YQG
 | | The structure of 14-3-3 and pNumb peptide | | 分子名称: | 14-3-3 protein eta, Peptide from Protein numb homolog | | 著者 | Chen, X, Liu, Z, Wen, W. | | 登録日 | 2017-11-06 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb/alpha-adaptin complex.
J. Biol. Chem., 293, 2018
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5ZCS
 | | 4.9 Angstrom Cryo-EM structure of human mTOR complex 2 | | 分子名称: | Rapamycin-insensitive companion of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, ... | | 著者 | Chen, X, Liu, M, Tian, Y, Wang, H, Wang, J, Xu, Y. | | 登録日 | 2018-02-20 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Cryo-EM structure of human mTOR complex 2.
Cell Res., 28, 2018
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6LBG
 | | Structure of OR51B2 bound FEM1C | | 分子名称: | Protein fem-1 homolog C,Peptide from Olfactory receptor 51B2, SULFATE ION | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LE6
 | | Structure of LNLPTQGRAR bound FEM1C | | 分子名称: | Protein fem-1 homolog C,10-mer peptide, SULFATE ION | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-24 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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3LUT
 | | A Structural Model for the Full-length Shaker Potassium Channel Kv1.2 | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ... | | 著者 | Chen, X, Ni, F, Wang, Q, Ma, J. | | 登録日 | 2010-02-18 | | 公開日 | 2010-06-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6LBF
 | | Crystal structure of FEM1B | | 分子名称: | Protein fem-1 homolog B, SULFATE ION | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.252 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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7DWS
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6LDP
 | | Structure of CDK5R1-bound FEM1C | | 分子名称: | Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-22 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LEN
 | | Structure of NS11 bound FEM1C | | 分子名称: | Protein fem-1 homolog C,NS11 peptide | | 著者 | Chen, x, Liao, S, Xu, C. | | 登録日 | 2019-11-25 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.383 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LBN
 | | Structure of SIL1-bound FEM1C | | 分子名称: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.899 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LF0
 | | Structure of FEM1C | | 分子名称: | Protein fem-1 homolog C, SULFATE ION | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-27 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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6LEY
 | | Structure of Sil1G bound FEM1C | | 分子名称: | Protein fem-1 homolog C,Peptide from Nucleotide exchange factor SIL1 | | 著者 | Chen, X, Liao, S, Xu, C. | | 登録日 | 2019-11-27 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
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7XWW
 | | Crystal structure of NTR in complex with BN-XB | | 分子名称: | 2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-8-[1-[(4-nitrophenyl)methyl]pyridin-1-ium-4-yl]-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.0^{3,7}]dodeca-1(12),4,6,8,10-pentaene, Dihydropteridine reductase, FLAVIN MONONUCLEOTIDE | | 著者 | Chen, X, Chen, J, Li, J.L. | | 登録日 | 2022-05-27 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of NTR in complex with BN-XB
To Be Published
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6LYN
 | | CD146 D4-D5/AA98 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AA98 Fab heavy chain, ... | | 著者 | Chen, X, Yan, X. | | 登録日 | 2020-02-14 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.776 Å) | | 主引用文献 | Structure basis for AA98 inhibition on the activation of endothelial cells mediated by CD146.
Iscience, 24, 2021
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7ENA
 | | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | | 登録日 | 2021-04-16 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-06-16 | | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
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