6WXY
 
 | | crystal structure of cA6-bound Card1 | | 分子名称: | Card1, cA6 | | 著者 | Rostol, J, Xie, W, Patel, D.J, Marraffini, L. | | 登録日 | 2020-05-12 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
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8T66
 | | cA6 bound Cam1 | | 分子名称: | Cam1, RNA (5'-R(P*AP*AP*AP*AP*A)-3') | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-15 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The CRISPR effector Cam1 mediates membrane depolarization for phage defence.
Nature, 625, 2024
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8T65
 | | cA4 bound Cam1 | | 分子名称: | Cam1, RNA (5'-R(P*AP*AP*AP*A)-3') | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-15 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The CRISPR effector Cam1 mediates membrane depolarization for phage defence.
Nature, 625, 2024
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8T64
 | | Apo Cam1(42-206) | | 分子名称: | Cam1 | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-15 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The CRISPR effector Cam1 mediates membrane depolarization for phage defence.
Nature, 625, 2024
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6WXX
 | | crystal structure of cA4-activated Card1 | | 分子名称: | Card1, MANGANESE (II) ION, cA4 | | 著者 | Rostol, J, Xie, W, Patel, D.J, Marraffini, L. | | 登録日 | 2020-05-12 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
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6WW9
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6WWA
 | | Crystal structure of human SHLD2-SHLD3-REV7 complex | | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera | | 著者 | Xie, W, Patel, D.J. | | 登録日 | 2020-05-08 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6XL1
 | | crystal structure of cA4-activated Card1(D294N) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Card1, MANGANESE (II) ION, ... | | 著者 | Rostol, J, Xie, W, Patel, D.J, Marraffini, L. | | 登録日 | 2020-06-27 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
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7R77
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7R78
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6WXW
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8URQ
 | | Spo11 core complex with gapped DNA | | 分子名称: | Antiviral protein SKI8, MAGNESIUM ION, Meiosis-specific protein SPO11, ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-10-26 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of the Spo11 core complex bound to DNA.
Nat.Struct.Mol.Biol., 2024
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8URU
 | | Spo11 core complex with hairpin DNA | | 分子名称: | Antiviral protein SKI8, Hairpin DNA, MAGNESIUM ION, ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-10-26 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of the Spo11 core complex bound to DNA.
Nat.Struct.Mol.Biol., 2024
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5DUN
 | | The crystal structure of OMe substituted twister ribozyme | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, RNA (54-MER) | | 著者 | Ren, A, Patel, D.J, Micura, R, Rajashankar, K.R. | | 登録日 | 2015-09-19 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.
Angew.Chem.Int.Ed.Engl., 54, 2015
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1JVC
 | | Dimeric DNA Quadruplex Containing Major Groove-Aligned A.T.A.T and G.C.G.C Tetrads Stabilized by Inter-Subunit Watson-Crick A:T and G:C Pairs | | 分子名称: | 5'-D(*GP*AP*GP*CP*AP*GP*GP*T)-3' | | 著者 | Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. | | 登録日 | 2001-08-29 | | 公開日 | 2001-10-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs.
J.Mol.Biol., 312, 2001
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1JJP
 | | A(GGGG) Pentad-Containing Dimeric DNA Quadruplex Involving Stacked G(anti)G(anti)G(anti)G(syn) Tetrads | | 分子名称: | 5'-D(*GP*GP*GP*AP*GP*GP*TP*TP*TP*GP*GP*GP*AP*T)-3' | | 著者 | Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. | | 登録日 | 2001-07-09 | | 公開日 | 2001-09-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.
J.Mol.Biol., 311, 2001
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5ELK
 | | Crystal structure of mouse Unkempt zinc fingers 4-6 (ZnF4-6), bound to RNA | | 分子名称: | RING finger protein unkempt homolog, RNA, ZINC ION | | 著者 | Teplova, M, Murn, J, Zarnack, K, Shi, Y, Patel, D.J. | | 登録日 | 2015-11-04 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt.
Nat.Struct.Mol.Biol., 23, 2016
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1UOW
 | | Calcium binding domain C2B | | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
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1UOV
 | | Calcium binding domain C2B | | 分子名称: | CALCIUM ION, GLYCEROL, SYNAPTOTAGMIN I | | 著者 | Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-09-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
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5ELH
 | | Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA | | 分子名称: | RING finger protein unkempt homolog, RNA (5'-R(*UP*UP*AP*UP*U)-3'), SULFATE ION, ... | | 著者 | Teplova, M, Murn, J, Zarnack, K, Shi, Y, Patel, D.J. | | 登録日 | 2015-11-04 | | 公開日 | 2015-12-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt.
Nat.Struct.Mol.Biol., 23, 2016
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1L4S
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1TJX
 | | Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain | | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | 登録日 | 2004-06-07 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain.
Protein Sci., 13, 2004
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1SWX
 | | Crystal structure of a human glycolipid transfer protein in apo-form | | 分子名称: | Glycolipid transfer protein, HEXANE | | 著者 | Malinina, L, Malakhova, M.L, Teplov, A, Brown, R.E, Patel, D.J. | | 登録日 | 2004-03-30 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural basis for glycosphingolipid transfer specificity.
Nature, 430, 2004
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1SX6
 | | Crystal structure of human Glycolipid Transfer protein in lactosylceramide-bound form | | 分子名称: | Glycolipid transfer protein, N-OCTANE, OLEIC ACID, ... | | 著者 | Malinina, L, Malakhova, M.L, Teplov, A, Brown, R.E, Patel, D.J. | | 登録日 | 2004-03-30 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for glycosphingolipid transfer specificity.
Nature, 430, 2004
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1JO1
 | | N7-Guanine Adduct of 2,7-diaminomitosene with DNA | | 分子名称: | 5'-D(*GP*TP*GP*(DAJ)GP*TP*AP*TP*AP*CP*CP*AP*C)-3', DECARBAMOYL-2,7-DIAMINOMITOSENE | | 著者 | Subramaniam, G, Paz, M.M, Kumar, G.S, Das, A, Palom, Y, Clement, C.C, Patel, D.J, Tomasz, M. | | 登録日 | 2001-07-26 | | 公開日 | 2001-09-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a guanine-N7-linked complex of the mitomycin C metabolite 2,7-diaminomitosene and DNA. Basis of sequence selectivity.
Biochemistry, 40, 2001
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