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5WLW
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BU of 5wlw by Molmil
Crystal Structure of the Human Mitochondrial Cysteine Desulfurase with active Cysteine Loop within ISCU1 active site, coordinating Zn ion. Complexed with human ISD11 and E. coli ACP1 at 3.3A.
分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
著者Boniecki, M.T, Cygler, M.
登録日2017-07-27
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.317 Å)
主引用文献Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
5WGB
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BU of 5wgb by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and E. coli ACP1 protein at 2.75A
分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
著者Boniecki, M.T, Cygler, M.
登録日2017-07-13
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
1DIB
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BU of 1dib by Molmil
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY345899
分子名称: 4-(7-AMINO-9-HYDROXY-1-OXO-3,3A,4,5-TETRAHYDRO-2,5,6,8,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALEN-2-YL)-PHENYLCARBONYL-GLUTAMI C ACID, METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Schmidt, A, Wu, H, MacKenzie, R.E, Chen, V.J, Bewly, J.R, Ray, J.E, Toth, J.E, Cygler, M.
登録日1999-11-29
公開日2000-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
1DIG
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BU of 1dig by Molmil
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY374571
分子名称: ACETATE ION, METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Schmidt, A, Wu, H, MacKenzie, R.E, Chen, V.J, Bewly, J.R, Ray, J.E, Toth, J.E, Cygler, M.
登録日1999-11-29
公開日2000-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
1DIA
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BU of 1dia by Molmil
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY249543
分子名称: METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [[[2-AMINO-5,6,7,8-TETRAHYDRO-4-HYDROXY-PYRIDO[2,3-D]PYRIMIDIN-6-YL]-ETHYL]-PHENYL]-CARBONYL-GLUTAMIC ACID
著者Schmidt, A, Wu, H, MacKenzie, R.E, Chen, V.J, Bewly, J.R, Ray, J.E, Toth, J.E, Cygler, M.
登録日1999-11-29
公開日2000-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
3LA0
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BU of 3la0 by Molmil
Crystal Structure of UreE from Helicobacter pylori (metal of unknown identity bound)
分子名称: UNKNOWN ATOM OR ION, Urease accessory protein ureE
著者Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2010-01-06
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites
Biochemistry, 49, 2010
3L9Z
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Crystal Structure of UreE from Helicobacter pylori (apo form)
分子名称: Urease accessory protein ureE
著者Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2010-01-06
公開日2010-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites
Biochemistry, 49, 2010
3E7J
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BU of 3e7j by Molmil
HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Heparinase II protein, ...
著者Shaya, D, Cygler, M.
登録日2008-08-18
公開日2008-12-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate.
J.Biol.Chem., 285, 2010
3E80
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Structure of Heparinase II complexed with heparan sulfate degradation disaccharide product
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Heparinase II protein, PHOSPHATE ION, ...
著者Shaya, D, Cygler, M.
登録日2008-08-19
公開日2008-12-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate.
J.Biol.Chem., 285, 2010
1F4Q
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BU of 1f4q by Molmil
CRYSTAL STRUCTURE OF APO GRANCALCIN
分子名称: GRANCALCIN
著者Jia, J, Han, Q, Borregaard, N, Lollike, K, Cygler, M.
登録日2000-06-08
公開日2000-09-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
J.Mol.Biol., 300, 2000
1CJL
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BU of 1cjl by Molmil
CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM
分子名称: PROCATHEPSIN L
著者Coulombe, R, Grochulski, P, Sivaraman, J, Cygler, M.
登録日1996-07-24
公開日1997-08-12
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
3G2Q
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BU of 3g2q by Molmil
Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with sinefungin
分子名称: PCZA361.24, SINEFUNGIN
著者Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2009-01-31
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics.
Chem.Biol., 16, 2009
3NY0
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BU of 3ny0 by Molmil
Crystal Structure of UreE from Helicobacter pylori (Ni2+ bound form)
分子名称: NICKEL (II) ION, Urease accessory protein ureE
著者Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2010-07-14
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites
Biochemistry, 49, 2010
1F4O
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BU of 1f4o by Molmil
CRYSTAL STRUCTURE OF GRANCALCIN WITH BOUND CALCIUM
分子名称: CALCIUM ION, GRANCALCIN
著者Jia, J, Han, Q, Borregaard, N, Lollike, K, Cygler, M.
登録日2000-06-08
公開日2000-09-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human grancalcin, a member of the penta-EF-hand protein family.
J.Mol.Biol., 300, 2000
6BYT
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BU of 6byt by Molmil
Complex structure of LOR107 mutant (R320) with tetrasaccharide substrate
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-3-O-sulfo-alpha-L-rhamnopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-3-O-sulfo-alpha-L-rhamnopyranose, CALCIUM ION, GLYCEROL, ...
著者Ulaganathan, T.S, Cygler, M.
登録日2017-12-21
公開日2018-02-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism.
J. Biol. Chem., 293, 2018
6BYP
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Structure of PL24 family Polysaccharide lyase-LOR107
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Ulaganathan, T.S, Cygler, M.
登録日2017-12-21
公開日2018-02-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism.
J. Biol. Chem., 293, 2018
3IKW
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BU of 3ikw by Molmil
Structure of Heparinase I from Bacteroides thetaiotaomicron
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Heparin lyase I
著者Garron, M.L, Cygler, M, Shaya, D.
登録日2009-08-06
公開日2009-09-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural snapshots of heparin depolymerization by heparin lyase I.
J.Biol.Chem., 284, 2009
2OV8
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BU of 2ov8 by Molmil
Crystal Structure of StaL
分子名称: StaL
著者Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2007-02-13
公開日2007-02-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis.
J.Biol.Chem., 282, 2007
2OVB
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Crystal Structure of StaL-sulfate complex
分子名称: SULFATE ION, StaL
著者Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2007-02-13
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis.
J.Biol.Chem., 282, 2007
2RB9
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Crystal structure of E.coli HypE
分子名称: HypE protein
著者Asinas, A.E, Rangarajan, E.S, Min, T, Matte, A, Proteau, A, Munger, C, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2007-09-18
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of [NiFe] hydrogenase maturation protein HypE from Escherichia coli and its interaction with HypF.
J.Bacteriol., 190, 2008
2Q1F
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Crystal structure of chondroitin sulfate lyase abc from bacteroides thetaiotaomicron wal2926
分子名称: CALCIUM ION, Chondroitinase, PHOSPHATE ION
著者Shaya, D, Cygler, M.
登録日2007-05-24
公開日2008-01-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Composite active site of chondroitin lyase ABC accepting both epimers of uronic acid.
Glycobiology, 18, 2008
2OVF
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Crystal Structure of StaL-PAP complex
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, StaL
著者Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2007-02-13
公開日2007-02-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis.
J.Biol.Chem., 282, 2007
2AHV
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Crystal Structure of Acyl-CoA transferase from E. coli O157:H7 (YdiF)-thioester complex with CoA- 1
分子名称: COENZYME A, putative enzyme YdiF
著者Rangarajan, E.S, Li, Y, Ajamian, E, Iannuzzi, P, Kernaghan, S.D, Fraser, M.E, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2005-07-28
公開日2005-11-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases.
J.Biol.Chem., 280, 2005
3G2P
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Crystal Structure of the Glycopeptide N-methyltransferase MtfA complexed with (S)-adenosyl-L-homocysteine (SAH)
分子名称: PCZA361.24, S-ADENOSYL-L-HOMOCYSTEINE
著者Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2009-01-31
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics.
Chem.Biol., 16, 2009
3B8O
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Structure of WzzE- Bacterial Polysaccharide Co-polymerase
分子名称: Lipopolysaccharide biosynthesis protein wzzE
著者Tocilj, A, Matte, A, Cygler, M.
登録日2007-11-01
公開日2008-01-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Bacterial polysaccharide co-polymerases share a common framework for control of polymer length
Nat.Struct.Mol.Biol., 15, 2008

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