Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3E80

Structure of Heparinase II complexed with heparan sulfate degradation disaccharide product

Summary for 3E80
Entry DOI10.2210/pdb3e80/pdb
Related3E7J
DescriptorHeparinase II protein, alpha-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywordsalpha and beta lyase fold, alpha6/alpha6 incomplete toroid, sugar binding protein, lyase
Biological sourcePedobacter heparinus
Total number of polymer chains3
Total formula weight258968.51
Authors
Shaya, D.,Cygler, M. (deposition date: 2008-08-19, release date: 2008-12-30, Last modification date: 2023-08-30)
Primary citationShaya, D.,Zhao, W.,Garron, M.L.,Xiao, Z.,Cui, Q.,Zhang, Z.,Sulea, T.,Linhardt, R.J.,Cygler, M.
Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate.
J.Biol.Chem., 285:20051-20061, 2010
Cited by
PubMed: 20404324
DOI: 10.1074/jbc.M110.101071
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.35 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon