6SGR
| Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc with cardiolipin | 分子名称: | DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB | 著者 | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | 登録日 | 2019-08-05 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Structure, 28, 2020
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4QCJ
| Crystal Structure of OdhI from Corynebacterium glutamicum | 分子名称: | Oxoglutarate dehydrogenase inhibitor | 著者 | Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M. | 登録日 | 2014-05-12 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model. J.Biotechnol., 191, 2014
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2BH7
| Crystal structure of a SeMet derivative of AmiD at 2.2 angstroms | 分子名称: | N-ACETYLMURAMOYL-L-ALANINE AMIDASE, SULFATE ION, ZINC ION | 著者 | Petrella, S, Herman, R, Sauvage, E, Genereux, C, Pennartz, A, Joris, B, Charlier, P. | 登録日 | 2005-01-07 | 公開日 | 2006-06-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Specific Structural Features of the N-Acetylmuramoyl-L-Alanine Amidase Amid from Escherichia Coli and Mechanistic Implications for Enzymes of This Family. J.Mol.Biol., 397, 2010
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3WOB
| Crystal structure of a prostate-specific WGA16 glycoprotein lectin, form I | 分子名称: | hypothetical protein | 著者 | Garenaux, E, Kanagawa, M, Tsuchiyama, T, Hori, K, Kanazawa, T, Goshima, A, Chiba, M, Yasue, H, Ikeda, A, Yamaguchi, Y, Sato, C, Kitajima, K. | 登録日 | 2013-12-26 | 公開日 | 2014-12-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery, Primary, and Crystal Structures and Capacitation-related Properties of a Prostate-derived Heparin-binding Protein WGA16 from Boar Sperm J.Biol.Chem., 290, 2015
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1S0I
| Trypanosoma cruzi trans-sialidase in complex with sialyl-lactose (Michaelis complex) | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, trans-sialidase | 著者 | Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M. | 登録日 | 2003-12-31 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase. Structure, 12, 2004
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4E94
| Crystal structure of MccF-like protein from Streptococcus pneumoniae | 分子名称: | GLYCEROL, MccC family protein, SULFATE ION | 著者 | Nocek, B, Tikhonov, A, Kwon, K, Severinov, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-03-20 | 公開日 | 2012-05-09 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | 主引用文献 | Crystal structure of MccF-like protein from Streptococcus pneumoniae TO BE PUBLISHED
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3WRI
| Crystal structure of P450cam | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H. | 登録日 | 2014-02-25 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of P450cam intermediate To be Published
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3WDL
| Crystal structure of 4-phosphopantoate-beta-alanine ligase complexed with ATP | 分子名称: | 4-phosphopantoate--beta-alanine ligase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Kishimoto, A, Kita, A, Ishibashi, T, Tomita, H, Yokooji, Y, Imanaka, T, Atomi, H, Miki, K. | 登録日 | 2013-06-19 | 公開日 | 2014-04-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of phosphopantothenate synthetase from Thermococcus kodakarensis Proteins, 82, 2014
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4EB4
| Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Dowiercial, A, Jarmula, A, Rypniewski, W.R, Wilk, P, Rode, W. | 登録日 | 2012-03-23 | 公開日 | 2012-05-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Crystal structure of mouse thymidylate synthase in tertiary complex with dUMP and raltitrexed reveals N-terminus architecture and two different active site conformations. Biomed Res Int, 2014, 2014
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3W7S
| Escherichia coli K12 YgjK complexed with glucose | 分子名称: | CALCIUM ION, Uncharacterized protein YgjK, alpha-D-glucopyranose | 著者 | Miyazaki, T, Kurakata, Y, Uechi, A, Yoshida, H, Kamitori, S, Sakano, Y, Nishikawa, A, Tonozuka, T. | 登録日 | 2013-03-06 | 公開日 | 2013-04-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the substrate specificity and function of Escherichia coli K12 YgjK, a glucosidase belonging to the glycoside hydrolase family 63. J.Mol.Biol., 381, 2008
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2JDM
| Mutant (S22A) of Pseudomonas aeruginosa lectin II (PA-IIL) complexed with methyl-a-L-fucopyranoside | 分子名称: | CALCIUM ION, FUCOSE-BINDING LECTIN PA-IIL, SULFATE ION, ... | 著者 | Adam, J, Pokorna, M, Sabin, C, Mitchell, E.P, Imberty, A, Wimmerova, M. | 登録日 | 2007-01-11 | 公開日 | 2007-06-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Engineering of Pa-Iil Lectin from Pseudomonas Aeruginosa - Unravelling the Role of the Specificity Loop for Sugar Preference. Bmc Struct.Biol., 7, 2007
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4EOR
| Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor NU6102 | 分子名称: | Cyclin-A2, Cyclin-dependent kinase 2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE | 著者 | Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D. | 登録日 | 2012-04-14 | 公開日 | 2013-02-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19, 2012
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1OZ1
| P38 MITOGEN-ACTIVATED KINASE IN COMPLEX WITH 4-AZAINDOLE INHIBITOR | 分子名称: | 3-(4-FLUOROPHENYL)-2-PYRIDIN-4-YL-1H-PYRROLO[3,2-B]PYRIDIN-1-OL, Mitogen-activated protein kinase 14 | 著者 | Lovejoy, B, Villasenor, A, Browner, M, Dunten, P. | 登録日 | 2003-04-07 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Design and synthesis of 4-azaindoles as inhibitors of p38 MAP kinase. J.Med.Chem., 46, 2003
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6SGU
| Cryo-EM structure of Escherichia coli AcrB and DARPin in Saposin A-nanodisc | 分子名称: | DARPin, Multidrug efflux pump subunit AcrB | 著者 | Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. | 登録日 | 2019-08-05 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Structure, 28, 2020
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1RER
| Crystal structure of the homotrimer of fusion glycoprotein E1 from Semliki Forest Virus. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gibbons, D.L, Vaney, M.C, Roussel, A, Vigouroux, A, Reilly, B, Kielian, M, Rey, F.A. | 登録日 | 2003-11-07 | 公開日 | 2004-01-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus. Nature, 427, 2004
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4EON
| Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with the inhibitor RO3306 | 分子名称: | (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2, ... | 著者 | Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D. | 登録日 | 2012-04-14 | 公開日 | 2013-02-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19, 2012
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6S8V
| Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain | 分子名称: | 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin | 著者 | Schiefner, A, Deuschle, F.-C, Skerra, A. | 登録日 | 2019-07-10 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications. Theranostics, 10, 2020
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4PVJ
| Phl p 4 I153V variant, a glucose oxidase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Pollen allergen Phl p 4.0202, ... | 著者 | Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. | 登録日 | 2014-03-17 | 公開日 | 2014-04-02 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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4E47
| SET7/9 in complex with inhibitor (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6- sulfonamide and S-adenosylmethionine | 分子名称: | (R)-(3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, BETA-MERCAPTOETHANOL, Histone-lysine N-methyltransferase SETD7, ... | 著者 | Walker, J.R, Ouyang, H, Dong, A, Fish, P, Cook, A, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2012-03-12 | 公開日 | 2012-03-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Setd7 in Complex with Inhibitor and SAM To be Published
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3WH2
| Human Mincle in complex with citrate | 分子名称: | C-type lectin domain family 4 member E, CALCIUM ION, CITRATE ANION | 著者 | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | 登録日 | 2013-08-21 | 公開日 | 2013-10-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL Proc.Natl.Acad.Sci.USA, 110, 2013
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3WMD
| Crystal structure of epoxide hydrolase MonBI | 分子名称: | Probable monensin biosynthesis isomerase | 著者 | Minami, A, Ose, T, Sato, K, Oikawa, A, Kuroki, K, Maenaka, K, Oguri, H, Oikawa, H. | 登録日 | 2013-11-16 | 公開日 | 2014-01-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Allosteric regulation of epoxide opening cascades by a pair of epoxide hydrolases in monensin biosynthesis Acs Chem.Biol., 9, 2014
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3WHD
| C-type lectin, human MCL | 分子名称: | C-type lectin domain family 4 member D, CALCIUM ION | 著者 | Furukawa, A, Kamishikiryo, J, Mori, D, Toyonaga, K, Okabe, Y, Toji, A, Kanda, R, Miyake, Y, Ose, T, Yamasaki, S, Maenaka, K. | 登録日 | 2013-08-24 | 公開日 | 2013-10-23 | 最終更新日 | 2013-12-11 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL Proc.Natl.Acad.Sci.USA, 110, 2013
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4Q0V
| Crystal structure of Acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in complex with L-ribulose | 分子名称: | COBALT (II) ION, COBALT HEXAMMINE(III), L-Ribose isomerase, ... | 著者 | Yoshida, H, Yoshihara, A, Teraoka, M, Izumori, K, Kamitori, S. | 登録日 | 2014-04-02 | 公開日 | 2014-05-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | X-ray structure of a novel L-ribose isomerase acting on a non-natural sugar L-ribose as its ideal substrate. Febs J., 281, 2014
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3WOC
| Crystal structure of a prostate-specific WGA16 glycoprotein lectin, form II | 分子名称: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ... | 著者 | Garenaux, E, Kanagawa, M, Tsuchiyama, T, Hori, K, Kanazawa, T, Goshima, A, Chiba, M, Yasue, H, Ikeda, A, Yamaguchi, Y, Sato, C, Kitajima, K. | 登録日 | 2013-12-26 | 公開日 | 2014-12-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery, Primary, and Crystal Structures and Capacitation-related Properties of a Prostate-derived Heparin-binding Protein WGA16 from Boar Sperm J.Biol.Chem., 290, 2015
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6SED
| Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB in complex with galactose | 分子名称: | ACETATE ION, Beta-galactosidase, FORMIC ACID, ... | 著者 | Rutkiewicz, M, Bujacz, A, Kaminska, P, Bujacz, G. | 登録日 | 2019-07-29 | 公開日 | 2019-09-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.233 Å) | 主引用文献 | Active Site Architecture and Reaction Mechanism Determination of Cold Adapted beta-d-galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 20, 2019
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