7WX2
| CBP-BrD complexed with NEO2734 | 分子名称: | 1,3-dimethyl-5-[2-(oxan-4-yl)-3-[2-(trifluoromethyloxy)ethyl]benzimidazol-5-yl]pyridin-2-one, CREB-binding protein | 著者 | Zeng, L, Lei, J.D. | 登録日 | 2022-02-14 | 公開日 | 2022-06-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Targeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer. Oncogene, 41, 2022
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7WWZ
| BRD4-BD1 complexed with NEO2734 | 分子名称: | 1,3-dimethyl-5-[2-(oxan-4-yl)-3-[2-(trifluoromethyloxy)ethyl]benzimidazol-5-yl]pyridin-2-one, Isoform C of Bromodomain-containing protein 4 | 著者 | Zeng, L, Lei, J.D. | 登録日 | 2022-02-14 | 公開日 | 2022-06-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Targeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer. Oncogene, 41, 2022
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7XEX
| Crystal strucutre of apoCasDinG | 分子名称: | CasDinG | 著者 | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | 登録日 | 2022-03-31 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XF0
| Crystal strucutre of CasDinG in complex with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CasDinG | 著者 | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | 登録日 | 2022-03-31 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XF1
| Crystal strucutre of apoCasDinG in complex with ssDNA | 分子名称: | CasDinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3') | 著者 | Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N. | 登録日 | 2022-03-31 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG1
| CryoEM structure of type IV-A Csf-crRNA binary complex | 分子名称: | Csf1, Csf2, Csf3, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-04-02 | 公開日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment Mol.Cell, 83, 2023
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7XG3
| CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex | 分子名称: | Csf1, Csf2, Csf3, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-04-02 | 公開日 | 2023-08-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XFZ
| CryoEM structure of type IV-A Csf-crRNAsp14-dsDNA ternary complex | 分子名称: | Csf1, Csf2, Csf3, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-04-02 | 公開日 | 2023-08-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG0
| CryoEM structure of type IV-A Csf-crRNA-dsDNA ternary complex | 分子名称: | Csf1, Csf2, Csf3, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-04-02 | 公開日 | 2023-08-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG4
| CryoEM structure of type IV-A CasDinG bound NTS-nicked Csf-crRNA-dsDNA quaternary complex in a second state | 分子名称: | Csf1, Csf2, Csf3, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-04-02 | 公開日 | 2023-08-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7XG2
| CryoEM structure of type IV-A NTS-nicked dsDNA bound Csf-crRNA ternary complex | 分子名称: | Csf1, Csf2, Csf3, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-04-02 | 公開日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment. Mol.Cell, 83, 2023
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7Y0I
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7YHQ
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7YHP
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7YHO
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7Y85
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to self RNA target | 分子名称: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y81
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to non-self RNA target | 分子名称: | MAGNESIUM ION, Non-self RNA target, RAMP superfamily protein, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y82
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to self RNA target | 分子名称: | MAGNESIUM ION, RAMP superfamily protein, Self RNA target, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y83
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to non-self RNA target | 分子名称: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y80
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA binary complex | 分子名称: | MAGNESIUM ION, RAMP superfamily protein, ZINC ION, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7Y84
| CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease | 分子名称: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | 著者 | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | 登録日 | 2022-06-22 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
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7YKF
| Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex | 分子名称: | Ephexin4, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKI
| Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR3 peptide | 分子名称: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKG
| Crystal structure of MAGI2 PDZ0-GK/pSGEF complex | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, SGEF | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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7YKH
| Crystal structure of MAGI2 PDZ0-GK domain in complex with phospho-SAPAP1 GBR2 peptide | 分子名称: | GLYCEROL, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | 著者 | Zhang, M, Lin, L, Zhu, J. | 登録日 | 2022-07-22 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs. Sci Adv, 9, 2023
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