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2HLE
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BU of 2hle by Molmil
Structural and biophysical characterization of the EPHB4-EPHRINB2 protein protein interaction and receptor specificity.
分子名称: Ephrin type-B receptor 4, Ephrin-B2
著者Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2006-07-06
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Biophysical Characterization of the EphB4-EphrinB2 Protein-Protein Interaction and Receptor Specificity.
J.Biol.Chem., 281, 2006
2HUJ
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BU of 2huj by Molmil
Crystal structure of a protein of uknown function (NP_471338.1) from Listeria innocua at 1.74 A resolution
分子名称: Lin2004 protein
著者Joint Center for Structural Genomics (JCSG)
登録日2006-07-26
公開日2006-08-08
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
Proteins, 71, 2008
2I40
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BU of 2i40 by Molmil
Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor
分子名称: 5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE, Cell division protein kinase 2, Cyclin-A2
著者Shewchuk, L.M.
登録日2006-08-21
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase
Bioorg.Med.Chem.Lett., 16, 2006
2IAY
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BU of 2iay by Molmil
Crystal structure of a duf1831 family protein (lp2179) from lactobacillus plantarum at 1.20 A resolution
分子名称: CHLORIDE ION, GLYCEROL, Hypothetical protein
著者Joint Center for Structural Genomics (JCSG)
登録日2006-09-08
公開日2006-10-10
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
2ICH
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BU of 2ich by Molmil
CRYSTAL STRUCTURE OF A PUTATIVE ATTH (NE1406) FROM NITROSOMONAS EUROPAEA AT 2.00 A RESOLUTION
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Putative AttH, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2006-09-12
公開日2006-10-03
最終更新日2023-01-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
Acta Crystallogr.,Sect.F, 66, 2010
6CZH
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BU of 6czh by Molmil
Structure of a redesigned beta barrel, mFAP0, bound to DFHBI
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP0
著者Doyle, L.A, Stoddard, B.L.
登録日2018-04-09
公開日2018-09-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6CVU
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BU of 6cvu by Molmil
Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine
分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ATP-dependent dethiobiotin synthetase BioD, SULFATE ION
著者Thompson, A.P, Wegener, K.L, Bruning, J.B, Polyak, S.W.
登録日2018-03-28
公開日2018-11-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.426 Å)
主引用文献Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes
Acs Catalysis, 8(11), 2018
6DO0
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BU of 6do0 by Molmil
Crystal structure of the multidrug binding transcriptional regulator LmrR in complex with Rhodium Bis-diphosphine Complex
分子名称: Transcriptional regulator, PadR-like family, bis[diethyl(methyl)-lambda~5~-phosphanyl]{bis[{[(2-{[2-(2,5-dioxopyrrolidin-1-yl)ethyl]amino}-2-oxoethyl)amino]methyl}(diethyl)-lambda~5~-phosphanyl]}rhodium
著者Zadvornyy, O.A, Laureanti, J.A, Katipamula, S, O'Hagan, M, Peters, J.W.
登録日2018-06-08
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Protein Scaffold Activates Catalytic CO2 Hydrogenation by a Rhodium Bis(diphosphine) Complex
Acs Catalysis, 9, 2019
6ECB
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BU of 6ecb by Molmil
Vlm2 thioesterase domain wild type structure 1
分子名称: Vlm2
著者Alonzo, D.A, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6CKP
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BU of 6ckp by Molmil
Crystal structure of a thioredoxin domain 2 from Brucella melitensis at 1.15 Angstrom resolution
分子名称: Thioredoxin
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-02-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of a thioredoxin domain 2 from Brucella melitensis at 1.15 Angstrom resolution
To be Published
6ECC
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BU of 6ecc by Molmil
Vlm2 thioesterase domain wild type structure 2
分子名称: Vlm2
著者Alonzo, D.A, Schmeing, T.M.
登録日2018-08-07
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid.
Nature, 565, 2019
6CZI
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BU of 6czi by Molmil
Structure of a redesigned beta barrel, mFAP1, bound to DFHBI
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP1
著者Doyle, L.A, Stoddard, B.L.
登録日2018-04-09
公開日2018-09-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
7OXB
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BU of 7oxb by Molmil
Crystal structure of EGFR double mutant (T790M/L858R) in complex with compound 6.
分子名称: 2-[2-(3-methoxyphenyl)pyrimidin-4-yl]-1'-prop-2-enoyl-spiro[5,6-dihydro-1~{H}-pyrrolo[3,2-c]pyridine-7,4'-piperidine]-4-one, Epidermal growth factor receptor
著者Collie, G.W.
登録日2021-06-22
公開日2021-10-20
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Discovery and optimization of covalent EGFR T790M/L858R mutant inhibitors".
Bioorg.Med.Chem.Lett., 2021
7P4R
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BU of 7p4r by Molmil
Ultra High Resolution X-ray Structure of Orthorhombic Bovine Pancreatic Ribonuclease at 100K
分子名称: ETHANOL, Ribonuclease pancreatic, SULFATE ION
著者Lisgarten, D.R, Palmer, R.A, Cooper, J.B, Naylor, C.E, Howlin, B.J, Lisgarten, J.N, Najmudin, S, Lobley, C.M.C.
登録日2021-07-12
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.85 Å)
主引用文献Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K.
BMC Chem, 17, 2023
6XF7
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BU of 6xf7 by Molmil
SLP
分子名称: Lambda 1 protein
著者Sutton, G, Sun, D.P, Fu, X.F, Kotecha, A, Hecksel, G.W, Clare, D.K, Zhang, P, Stuart, D, Boyce, M.
登録日2020-06-15
公開日2020-09-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Assembly intermediates of orthoreovirus captured in the cell.
Nat Commun, 11, 2020
6A69
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BU of 6a69 by Molmil
Cryo-EM structure of a P-type ATPase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroplastin, Plasma membrane calcium-transporting ATPase 1
著者Gong, D.S, Chi, X.M, Ren, K, Huang, G.X.Y, Zhou, G.W, Yan, N, Lei, J.L, Zhou, Q.
登録日2018-06-27
公開日2018-09-19
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin.
Nat Commun, 9, 2018
5EJ2
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BU of 5ej2 by Molmil
Crystal structure of Carveol dehydrogenase from Mycobacterium avium in complex with NAD
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-10-31
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Sci Rep, 7, 2017
4NJ3
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BU of 4nj3 by Molmil
Modulating the interaction between CDK2 and Cyclin A with a Quinoline-based inhibitor
分子名称: 6-(3-chlorophenyl)-2-{[(2S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid, Cyclin-dependent kinase 2
著者Fischmann, T.O, Hruza, A.W.
登録日2013-11-08
公開日2013-11-27
最終更新日2014-01-08
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor.
Bioorg.Med.Chem.Lett., 24, 2014
4O2D
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BU of 4o2d by Molmil
Crystal structure of aspartyl-tRNA synthetase from Mycobacterium smegmatis with bound aspartic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ASPARTIC ACID, Aspartate--tRNA ligase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-12-17
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3TDE
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BU of 3tde by Molmil
Crystal structure of S-adenosylmethionine synthetase Rv1392 from Mycobacterium tuberculosis
分子名称: S-adenosylmethionine synthase, SODIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-10
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3SWX
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BU of 3swx by Molmil
Crystal structure of a probable enoyl-CoA hydratase/isomerase from Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Probable enoyl-CoA hydratase/isomerase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-14
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3TRR
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BU of 3trr by Molmil
Crystal structure of a probable enoyl-CoA hydratase/isomerase from Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-09
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3TX2
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BU of 3tx2 by Molmil
Structure of a Probable 6-phosphogluconolactonase from Mycobacterium abscessus
分子名称: BENZOIC ACID, GLYCEROL, Probable 6-phosphogluconolactonase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-09-22
公開日2011-10-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3SWO
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BU of 3swo by Molmil
Crystal structure of a glutaryl-coa dehydrogenase from mycobacterium smegmatis in complex with FADH2
分子名称: 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-14
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3SZ8
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BU of 3sz8 by Molmil
Crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from Burkholderia pseudomallei
分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase 2, ACETATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-18
公開日2011-08-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013

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