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2Z3E
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BU of 2z3e by Molmil
A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase
分子名称: ACE VAL Z3E LEU KCQ peptide, GLYCEROL, Replicase polyprotein 1ab (pp1ab)
著者Yin, J.
登録日2007-06-04
公開日2007-07-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase
J.Mol.Biol., 371, 2007
2Z8N
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BU of 2z8n by Molmil
Structural basis for the catalytic mechanism of phosphothreonine lyase
分子名称: 27.5 kDa virulence protein, SULFATE ION
著者Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J.
登録日2007-09-07
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
2Z8M
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BU of 2z8m by Molmil
Structural basis for the catalytic mechanism of phosphothreonine lyase
分子名称: 27.5 kDa virulence protein
著者Chen, L, Wang, H, Gu, L, Huang, N, Zhou, J.M, Chai, J.
登録日2007-09-07
公開日2007-12-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the catalytic mechanism of phosphothreonine lyase.
Nat.Struct.Mol.Biol., 15, 2008
6NPK
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BU of 6npk by Molmil
Structure of the TM domain
分子名称: Solute carrier family 12 (sodium/potassium/chloride transporter), member 2
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6NPJ
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BU of 6npj by Molmil
Structure of the NKCC1 CTD
分子名称: Sodium-potassium-chloride cotransporter 1
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
8CWW
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BU of 8cww by Molmil
Structure of S. cerevisiae Hop1 CBR bound to a nucleosome
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
登録日2022-05-19
公開日2023-06-07
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
6NPL
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BU of 6npl by Molmil
Cryo-EM structure of NKCC1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
8CZE
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BU of 8cze by Molmil
Structure of a Xenopus Nucleosome with Widom 601 DNA
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
登録日2022-05-24
公開日2023-06-07
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
6NPH
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BU of 6nph by Molmil
Structure of NKCC1 TM domain
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2020-01-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
8IYX
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BU of 8iyx by Molmil
Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365
分子名称: 1-[4-(3-chlorophenyl)phenyl]carbonyl-4-[2-(4-phenylmethoxyphenyl)ethanoylamino]piperidine-4-carboxylic acid, Probable G-protein coupled receptor 34,YL-365
著者Jia, G.W, Wang, X, Zhang, C.B, Dong, H.H, Su, Z.M.
登録日2023-04-06
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DZP
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BU of 8dzp by Molmil
momSalB bound Kappa Opioid Receptor in complex with Gi1
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Fay, J.F, Che, T.
登録日2022-08-08
公開日2023-05-03
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
8DZQ
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BU of 8dzq by Molmil
momSalB bound Kappa Opioid Receptor in complex with GoA
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ...
著者Fay, J.F, Che, T.
登録日2022-08-08
公開日2023-05-03
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
8DZS
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BU of 8dzs by Molmil
GR89,696 bound Kappa Opioid Receptor in complex with Gz
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(z) subunit alpha, ...
著者Fay, J.F, Che, T.
登録日2022-08-08
公開日2023-05-03
最終更新日2023-05-24
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
8DZR
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BU of 8dzr by Molmil
GR89,696 bound Kappa Opioid Receptor in complex with gustducin
分子名称: G alpha gustducin protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Fay, J.F, Che, T.
登録日2022-08-08
公開日2023-05-03
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Ligand and G-protein selectivity in the kappa-opioid receptor.
Nature, 617, 2023
8DOC
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BU of 8doc by Molmil
Crystal structure of RPE65 in complex with compound 16e and palmitate
分子名称: (1R)-1-[3-(cyclohexylmethoxy)phenyl]-3-(methylamino)propan-1-ol, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FE (II) ION, ...
著者Bassetto, M, Kiser, P.D.
登録日2022-07-12
公開日2023-05-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif.
J.Med.Chem., 66, 2023
8E1P
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BU of 8e1p by Molmil
Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ...
著者Sarkar, A, Kumar, S, Wilson, I.A.
登録日2022-08-11
公開日2023-06-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.82 Å)
主引用文献Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
Cell Rep Med, 4, 2023
6LS2
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BU of 6ls2 by Molmil
Marsupenaeus japonicus ferritin mutant (T158H) pH 4.0
分子名称: Ferritin
著者Zhao, G, Tan, X, Zhang, T.
登録日2020-01-16
公開日2020-11-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking.
Commun Chem, 2020
6LRW
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BU of 6lrw by Molmil
Marsupenaeus japonicus ferritin mutant(T158H) pH 7.0
分子名称: Ferritin
著者Zhao, G, Tan, X, Zhang, T.
登録日2020-01-16
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking.
Commun Chem, 2020
7ULI
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BU of 7uli by Molmil
Apo HMG-CoA Reductase from Arabidopsis thaliana (HMG1)
分子名称: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
著者Haywood, J, Bond, C.S.
登録日2022-04-05
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action.
Nat Commun, 13, 2022
3ENS
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BU of 3ens by Molmil
Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Activated factor Xa heavy chain, ...
著者Klei, H.E.
登録日2008-09-25
公開日2008-12-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors.
J.Med.Chem., 51, 2008
4LCZ
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BU of 4lcz by Molmil
Crystal structure of a multilayer-packed major light-harvesting complex
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者Wan, T, Li, M, Chang, W.R.
登録日2013-06-24
公開日2014-05-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a multilayer packed major light-harvesting complex: implications for grana stacking in higher plants.
Mol Plant, 7, 2014
8H69
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BU of 8h69 by Molmil
Cryo-EM structure of influenza RNA polymerase
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ...
著者Li, H, Wu, Y, Liang, H, Liu, Y.
登録日2022-10-16
公開日2023-06-28
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles.
Nat.Struct.Mol.Biol., 30, 2023
6INH
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A glycosyltransferase with UDP and the substrate
分子名称: 1-O-[(8alpha,9beta,10alpha,13alpha)-13-(beta-D-glucopyranosyloxy)-18-oxokaur-16-en-18-yl]-beta-D-glucopyranose, GLYCEROL, UDP-glycosyltransferase 76G1, ...
著者Zhu, X.
登録日2018-10-25
公開日2019-07-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations.
Nat Commun, 10, 2019
4IOU
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BU of 4iou by Molmil
Crystal structure of the HIV-1 Vif binding, catalytically active domain of APOBEC3F
分子名称: DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION
著者Bohn, M, Shandilya, S.M.D, Schiffer, C.A.
登録日2013-01-08
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain.
Structure, 21, 2013
6LRV
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BU of 6lrv by Molmil
Marsupenaeus japonicus ferritin mutant(T158H) pH9.0
分子名称: Ferritin
著者Zhao, G, Tan, X, Zhang, T.
登録日2020-01-16
公開日2020-11-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking.
Commun Chem, 2020

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件を2024-08-07に公開中

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