1A4F
 
 | | BAR-HEADED GOOSE HEMOGLOBIN (OXY FORM) | | 分子名称: | HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), OXYGEN MOLECULE, ... | | 著者 | Zhang, J, Gu, X. | | 登録日 | 1998-01-29 | | 公開日 | 1998-04-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of a high oxygen affinity species of haemoglobin (bar-headed goose haemoglobin in the oxy form).
J.Mol.Biol., 255, 1996
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3BAK
 | | N298S mutant of Human Pancreatic Alpha-Amylase in complex with nitrate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ... | | 著者 | Fredriksen, J.R, Maurus, R, Brayer, G.D. | | 登録日 | 2007-11-08 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
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5U15
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3BAW
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7UYA
 | | Inhibitor bound VIM1 | | 分子名称: | (2M)-4'-(piperidin-4-yl)-2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-sulfonamide, Beta-lactamase VIM-1, ZINC ION | | 著者 | Fischmann, T.O, Scapin, G. | | 登録日 | 2022-05-06 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | Structure Guided Discovery of Novel Pan Metallo-beta-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.
J.Med.Chem., 67, 2024
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7UYD
 | | Inhibitor bound VIM1 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Metallo-beta-lactamase VIM-2-like protein, ... | | 著者 | Fischmann, T.O, Scapin, G. | | 登録日 | 2022-05-06 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structure Guided Discovery of Novel Pan Metallo-beta-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.
J.Med.Chem., 67, 2024
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3BAI
 | | Human Pancreatic Alpha Amylase with Bound Nitrate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NITRATE ION, ... | | 著者 | Fredriksen, J.R, Maurus, R, Brayer, G.D. | | 登録日 | 2007-11-07 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
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5TPP
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5TPL
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5U0R
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5TQA
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5TRP
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7W0W
 | | The novel membrane-proximal sensing mechanism in a broad-ligand binding chemoreceptor McpA of Bacillus velezensis | | 分子名称: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Feng, H.C, Shen, Q.R, Zhang, R.F. | | 登録日 | 2021-11-18 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.247 Å) | | 主引用文献 | Signal binding at both modules of its dCache domain enables the McpA chemoreceptor of Bacillus velezensis to sense different ligands.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5U0U
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4HK3
 | | I2 Fab (unbound) from CH65-CH67 Lineage | | 分子名称: | I2 heavy chain, I2 light chain | | 著者 | Schmidt, A.G, Harrison, S.C. | | 登録日 | 2012-10-14 | | 公開日 | 2012-11-21 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4HKX
 | | Influenza hemagglutinin in complex with CH67 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CH67 heavy chain, CH67 light chain, ... | | 著者 | Schmidt, A.G, Harrison, S.C. | | 登録日 | 2012-10-15 | | 公開日 | 2012-11-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4HK0
 | | UCA Fab (unbound) from CH65-CH67 Lineage | | 分子名称: | UCA heavy chain, UCA light chain | | 著者 | Schmidt, A.G, Harrison, S.C. | | 登録日 | 2012-10-14 | | 公開日 | 2012-11-21 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | | 主引用文献 | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5UGY
 | | Influenza hemagglutinin in complex with a neutralizing antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH65 heavy chain, ... | | 著者 | Whittle, J.R.R, Jenni, S, Harrison, S.C. | | 登録日 | 2017-01-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
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4HKB
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8JLZ
 | | ST1936-5HT6R complex | | 分子名称: | 2-(5-chloranyl-2-methyl-1~{H}-indol-3-yl)-N,N-dimethyl-ethanamine, 5-hydroxytryptamine receptor 6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wen, X, Sun, J. | | 登録日 | 2023-06-04 | | 公開日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural insight into the selective agonist ST1936 binding of serotonin receptor 5-HT6.
Biochem.Biophys.Res.Commun., 671, 2023
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4EMM
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3FLI
 | | Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR) | | 分子名称: | 1-methylethyl 3-[(3,4-difluorophenyl)carbonyl]-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate, Bile acid receptor | | 著者 | Foster, P.G, Stout, T.J. | | 登録日 | 2008-12-18 | | 公開日 | 2009-12-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR).
J.Med.Chem., 52, 2009
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1L8R
 | | Structure of the Retinal Determination Protein Dachshund Reveals a DNA-Binding Motif | | 分子名称: | Dachshund | | 著者 | Kim, S.S, Zhang, R, Braunstein, S.E, Joachimiak, A, Cvekl, A, Hegde, R.S. | | 登録日 | 2002-03-21 | | 公開日 | 2002-06-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of the retinal determination protein Dachshund reveals a DNA binding motif.
Structure, 10, 2002
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7CN2
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5Z9J
 | | Identification of the functions of unusual cytochrome p450-like monooxygenases involved in microbial secondary metablism | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like enzyme, TRIS(HYDROXYETHYL)AMINOMETHANE | | 著者 | Lu, M, Lin, L, Zhang, C, Chen, Y. | | 登録日 | 2018-02-03 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases.
Chembiochem, 2020
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