7B1G
| TRPC4 in complex with Calmodulin | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-24 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B0J
| TRPC4 in LMNG detergent | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CALCIUM ION, Transient receptor potential cation channel subfamily c member 4a | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-20 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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7B05
| TRPC4 in complex with inhibitor GFB-8749 | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, ... | 著者 | Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S. | 登録日 | 2020-11-18 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of TRPC4 regulation by calmodulin and pharmacological agents. Elife, 9, 2020
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1HP7
| A 2.1 ANGSTROM STRUCTURE OF AN UNCLEAVED ALPHA-1-ANTITRYPSIN SHOWS VARIABILITY OF THE REACTIVE CENTER AND OTHER LOOPS | 分子名称: | ALPHA-1-ANTITRYPSIN, BETA-MERCAPTOETHANOL, ZINC ION | 著者 | Kim, S.-J, Woo, J.-R, Seo, E.J, Yu, M.-H, Ryu, S.-E. | 登録日 | 2000-12-12 | 公開日 | 2001-03-14 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops. J.Mol.Biol., 306, 2001
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7S96
| Structure of the Light Harvesting Complex PC577 from Hemiselmis pacifica | 分子名称: | 15,16-DIHYDROBILIVERDIN, PHYCOCYANOBILIN, Phycoerythrin alpha subunit 1, ... | 著者 | Jeffrey, P.D, Spangler, L.C, Scholes, G.D. | 登録日 | 2021-09-20 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Controllable Phycobilin Modification: An Alternative Photoacclimation Response in Cryptophyte Algae. Acs Cent.Sci., 8, 2022
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7S97
| Structure of the Photoacclimated Light Harvesting Complex PC577 from Hemiselmis pacifica | 分子名称: | 15,16-DIHYDROBILIVERDIN, PHYCOCYANOBILIN, Phycoerythrin alpha subunit 1, ... | 著者 | Jeffrey, P.D, Spangler, L.C, Scholes, G.D. | 登録日 | 2021-09-20 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Controllable Phycobilin Modification: An Alternative Photoacclimation Response in Cryptophyte Algae. Acs Cent.Sci., 8, 2022
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3LRE
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5LPH
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4OAS
| co-crystal structure of MDM2 (17-111) in complex with compound 25 | 分子名称: | E3 ubiquitin-protein ligase Mdm2, SULFATE ION, [(3R,5R,6S)-1-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetic acid | 著者 | Huang, X. | 登録日 | 2014-01-06 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2-p53 Inhibitor in Clinical Development. J.Med.Chem., 57, 2014
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3EOP
| Crystal Structure of the DUF55 domain of human thymocyte nuclear protein 1 | 分子名称: | SULFATE ION, Thymocyte nuclear protein 1 | 著者 | Yu, F, Song, A, Xu, C, Sun, L, Li, L, Tang, L, Hu, H, He, J. | 登録日 | 2008-09-29 | 公開日 | 2009-09-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Determining the DUF55-domain structure of human thymocyte nuclear protein 1 from crystals partially twinned by tetartohedry Acta Crystallogr.,Sect.D, 65, 2009
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3NBX
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8E1O
| Crystal structure of hTEAD2 bound to a methoxypyridine lipid pocket binder | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-methoxy-N-({3-[2-(methylamino)-2-oxoethyl]phenyl}methyl)-4-{(E)-2-[trans-4-(trifluoromethyl)cyclohexyl]ethenyl}pyridine-2-carboxamide, Transcriptional enhancer factor TEF-4 | 著者 | Noland, C.L, Dey, A, Zbieg, J, Crawford, J. | 登録日 | 2022-08-10 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation Biorxiv, 2024
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7TLF
| Structure of the photoacclimated Light Harvesting Complex PE545 from Proteomonas sulcata | 分子名称: | 15,16-DIHYDROBILIVERDIN, PHYCOERYTHROBILIN, Phycoerythrin alpha-subunit 1, ... | 著者 | Jeffrey, P.D, Spangler, L.C, Scholes, G.D. | 登録日 | 2022-01-18 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Controllable Phycobilin Modification: An Alternative Photoacclimation Response in Cryptophyte Algae. Acs Cent.Sci., 8, 2022
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7TJA
| Structure of the Light Harvesting Complex PE545 from Proteomonas sulcata | 分子名称: | 15,16-DIHYDROBILIVERDIN, MAGNESIUM ION, PHYCOERYTHROBILIN, ... | 著者 | Jeffrey, P.D, Spangler, L.C, Scholes, G.D. | 登録日 | 2022-01-15 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Controllable Phycobilin Modification: An Alternative Photoacclimation Response in Cryptophyte Algae. Acs Cent.Sci., 8, 2022
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4X1U
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4X0X
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5YEU
| Structural and mechanistic analyses reveal a unique Cas4-like protein in the mimivirus virophage resistance element system | 分子名称: | MAGNESIUM ION, Uncharacterized protein R354 | 著者 | Dou, C, Yu, M.J, Gu, Y.J, Cheng, W. | 登録日 | 2017-09-19 | 公開日 | 2018-07-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System. Iscience, 3, 2018
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5YET
| Structure of R354_WT | 分子名称: | Uncharacterized protein R354 | 著者 | Dou, C, Yu, M.J, Gu, Y.J, Cheng, W. | 登録日 | 2017-09-19 | 公開日 | 2018-06-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | 主引用文献 | Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System. Iscience, 3, 2018
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3IOS
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7DNH
| 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of 2H3 | 分子名称: | Major capsid protein L1, The heavy chain of 2H3 Fab fragment, The light chain of 2H3 Fab fragment | 著者 | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | 登録日 | 2020-12-09 | 公開日 | 2020-12-30 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding. J.Virol., 95, 2021
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7DNK
| 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of 5G9 | 分子名称: | Major capsid protein L1, The heavy chain of 5G9 Fab fragment, The light chain of 5G9 Fab fragment | 著者 | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | 登録日 | 2020-12-09 | 公開日 | 2020-12-30 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (6.41 Å) | 主引用文献 | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding. J.Virol., 95, 2021
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7DNL
| 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of A4B4 | 分子名称: | Major capsid protein L1, The heavy chain of 2H3 Fab fragment, The light chain of A4B4 Fab fragment | 著者 | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | 登録日 | 2020-12-09 | 公開日 | 2020-12-30 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding. J.Virol., 95, 2021
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6EWH
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2OP1
| Crystal structure of plasmodium falciparum enoyl ACP reductase with triclosan reductase | 分子名称: | 2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL, Enoyl-acyl carrier reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Tsai, H. | 登録日 | 2007-01-26 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy J.Biol.Chem., 282, 2007
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6TWN
| Crystal structure of Talin1 R7R8 in complex with CDK1 (206-223) | 分子名称: | CHLORIDE ION, Cyclin-dependent kinase 1, GLYCEROL, ... | 著者 | Zacharchenko, T, Muench, S.P, Goult, B.T. | 登録日 | 2020-01-13 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1. J.Biol.Chem., 297, 2021
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