6ACI
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6IHG
| N terminal domain of Mycobacterium avium complex Lon protease | 分子名称: | Lon protease | 著者 | Chen, X.Y, Zhang, S.J, Bi, F.K, Guo, C.Y, Yao, H.W, Lin, D.H. | 登録日 | 2018-09-29 | 公開日 | 2019-08-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex. Protein Sci., 28, 2019
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6AC0
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6AC5
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7KHL
| BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate) | 分子名称: | Bromodomain-containing protein 4, GLYCEROL, methyl 7-(3,5-difluoropyridin-2-yl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxylate | 著者 | Murray, J.M. | 登録日 | 2020-10-21 | 公開日 | 2021-02-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.286 Å) | 主引用文献 | Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. J.Med.Chem., 64, 2021
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7KHH
| Ternary complex of VHL/BRD4-BD1/Compound9 (4-(3,5-difluoropyridin-2-yl)-N-(11-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecyl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxamide) | 分子名称: | Bromodomain-containing protein 4, Elongin-B, Elongin-C, ... | 著者 | Murray, J.M. | 登録日 | 2020-10-21 | 公開日 | 2021-02-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.281 Å) | 主引用文献 | Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. J.Med.Chem., 64, 2021
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6AY2
| Structure of CathB with covalently linked Compound 28 | 分子名称: | Cathepsin B, N~1~-[(2S)-1-amino-5-(carbamoylamino)pentan-2-yl]-N'~1~-[(1R)-1-(thiophen-3-yl)ethyl]cyclobutane-1,1-dicarboxamide | 著者 | Kiefer, J.R, Steinbacher, S. | 登録日 | 2017-09-07 | 公開日 | 2017-12-27 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. J. Med. Chem., 61, 2018
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6A6J
| Crystal structure of Zebra fish Y-box protein1 (YB-1) Cold-shock domain in complex with 6mer m5C RNA | 分子名称: | RNA (5'-R(P*CP*AP*UP*(5MC)P*U)-3'), ZINC ION, Zebra fish Y-box protein1 (YB-1) | 著者 | Zhang, M.M, Wu, B.X, Huang, Y, Ma, J.B. | 登録日 | 2018-06-28 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.255 Å) | 主引用文献 | RNA 5-Methylcytosine Facilitates the Maternal-to-Zygotic Transition by Preventing Maternal mRNA Decay. Mol.Cell, 75, 2019
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6VBK
| Crystal structure of N-terminal domain of Mycobacterium tuberculosis complex Lon protease | 分子名称: | GLYCEROL, Lon211 | 著者 | Bi, F.K, Chen, C, Chen, X.Y, Guo, C.Y, Lin, D.H. | 登録日 | 2019-12-19 | 公開日 | 2020-12-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex. Protein Sci., 28, 2019
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6IVU
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6IVS
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3ISF
| Structure of non-mineralized Bfrb (as-isolated) from Pseudomonas aeruginosa to 2.07A Resolution | 分子名称: | Bacterioferritin, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M. | 登録日 | 2009-08-25 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center Biochemistry, 49, 2010
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3ISE
| Structure of mineralized Bfrb (double soak) from Pseudomonas aeruginosa to 2.8A Resolution | 分子名称: | Bacterioferritin, FE (III) ION, POTASSIUM ION, ... | 著者 | Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M. | 登録日 | 2009-08-25 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center Biochemistry, 49, 2010
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8HE7
| ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | 分子名称: | 1-[[4-fluoranyl-3-(3-oxidanylidene-4-pentan-3-yl-piperazin-1-yl)carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1, processed C-terminus, ... | 著者 | Wang, X.Y, Zhou, J, Xu, B.L. | 登録日 | 2022-11-07 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of Quinazoline-2,4(1 H ,3 H )-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis. J.Med.Chem., 66, 2023
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8HE8
| Human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | 分子名称: | 1-[[4-fluoranyl-3-(3-oxidanylidene-4-pentan-3-yl-piperazin-1-yl)carbonyl-phenyl]methyl]quinazoline-2,4-dione, GLYCEROL, Poly [ADP-ribose] polymerase 2 | 著者 | Wang, X.Y, Xu, B.L, Zhou, J. | 登録日 | 2022-11-07 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Discovery of Quinazoline-2,4(1 H ,3 H )-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis. J.Med.Chem., 66, 2023
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3IS7
| Structure of mineralized Bfrb from Pseudomonas aeruginosa to 2.1A Resolution | 分子名称: | Bacterioferritin, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M. | 登録日 | 2009-08-25 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center Biochemistry, 49, 2010
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3IS8
| Structure of mineralized Bfrb soaked with FeSO4 from Pseudomonas aeruginosa to 2.25A Resolution | 分子名称: | Bacterioferritin, FE (II) ION, POTASSIUM ION, ... | 著者 | Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M. | 登録日 | 2009-08-25 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center Biochemistry, 49, 2010
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3KXT
| Crystal structure of Sulfolobus Cren7-dsDNA complex | 分子名称: | 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', Chromatin protein Cren7 | 著者 | Feng, Y, Wang, J. | 登録日 | 2009-12-03 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex Protein Sci., 19, 2010
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8FFD
| Crystal structure of manganeese bound Dps protein (PA0962) from Pseudomonas aeruginosa (cubic form) | 分子名称: | L(+)-TARTARIC ACID, MANGANESE (II) ION, Probable dna-binding stress protein | 著者 | Lovell, S, Seibold, S, Battaile, K.P, Rivera, M. | 登録日 | 2022-12-08 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity. Int J Mol Sci, 24, 2023
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8FF9
| Crystal structure of Apo Dps protein (PA0962) from Pseudomonas aeruginosa (orthorhombic form) | 分子名称: | CHLORIDE ION, Probable dna-binding stress protein, SODIUM ION, ... | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Rivera, M. | 登録日 | 2022-12-08 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity. Int J Mol Sci, 24, 2023
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8FFA
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8FFC
| Crystal structure of iron bound Dps protein (PA0962) from Pseudomonas aeruginosa (cubic form) | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE (II) ION, Probable dna-binding stress protein | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Rivera, M. | 登録日 | 2022-12-08 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity. Int J Mol Sci, 24, 2023
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8FFB
| Crystal structure of iron bound Dps protein (PA0962) from Pseudomonas aeruginosa (orthorhombic form) | 分子名称: | FE (II) ION, Probable dna-binding stress protein | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Rivera, M. | 登録日 | 2022-12-08 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity. Int J Mol Sci, 24, 2023
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2JTM
| Solution structure of Sso6901 from Sulfolobus solfataricus P2 | 分子名称: | Putative uncharacterized protein | 著者 | Feng, Y, Guo, L, Huang, L, Wang, J. | 登録日 | 2007-08-03 | 公開日 | 2008-04-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea Nucleic Acids Res., 36, 2008
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4GL2
| Structural Basis for dsRNA duplex backbone recognition by MDA5 | 分子名称: | Interferon-induced helicase C domain-containing protein 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(*AP*UP*CP*CP*GP*CP*GP*GP*CP*CP*CP*U)-3'), ... | 著者 | Wu, B, Hur, S. | 登録日 | 2012-08-13 | 公開日 | 2013-01-09 | 最終更新日 | 2013-02-06 | 実験手法 | X-RAY DIFFRACTION (3.557 Å) | 主引用文献 | Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5. Cell(Cambridge,Mass.), 152, 2013
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