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4N0O
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BU of 4n0o by Molmil
Complex structure of Arterivirus nonstructural protein 10 (helicase) with DNA
分子名称: CALCIUM ION, DNA, Replicase polyprotein 1ab, ...
著者Deng, Z, Chen, Z.
登録日2013-10-02
公開日2014-01-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase.
Nucleic Acids Res., 42, 2014
4N0N
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BU of 4n0n by Molmil
Crystal structure of Arterivirus nonstructural protein 10 (helicase)
分子名称: MAGNESIUM ION, Replicase polyprotein 1ab, SULFATE ION, ...
著者Deng, Z, Chen, Z.
登録日2013-10-02
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase.
Nucleic Acids Res., 42, 2014
3BPL
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BU of 3bpl by Molmil
Crystal structure of the IL4-IL4R-Common Gamma ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Garcia, K.C.
登録日2007-12-18
公開日2008-02-05
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
3BPO
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BU of 3bpo by Molmil
Crystal structure of the IL13-IL4R-IL13Ra ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 13, ...
著者Garcia, K.C.
登録日2007-12-18
公開日2008-02-05
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
3BPN
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BU of 3bpn by Molmil
Crystal structure of the IL4-IL4R-IL13Ra ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13 receptor alpha-1 chain, Interleukin-4, ...
著者Garcia, K.C.
登録日2007-12-18
公開日2008-02-05
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Molecular and Structural Basis of Cytokine Receptor Pleiotropy in the Interleukin-4/13 System.
Cell(Cambridge,Mass.), 132, 2008
5KEK
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BU of 5kek by Molmil
Structure Determination of a Self-Assembling DNA Crystal
分子名称: CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*GP*T)-3'), ...
著者Simmons, C.R, Birktoft, J.J, Seeman, N.C, Yan, H.
登録日2016-06-09
公開日2016-08-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.098 Å)
主引用文献Construction and Structure Determination of a Three-Dimensional DNA Crystal.
J.Am.Chem.Soc., 138, 2016
5KEO
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BU of 5keo by Molmil
Structure Determination of a Self-Assembling DNA Crystal
分子名称: CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*GP*T)-3'), ...
著者Simmons, C.R, Birktoft, J.J, Seeman, N.C, Yan, H.
登録日2016-06-09
公開日2016-08-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Construction and Structure Determination of a Three-Dimensional DNA Crystal.
J.Am.Chem.Soc., 138, 2016
7YF5
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BU of 7yf5 by Molmil
Crystal Structure of the UDPGA Binding Domain of the Human Phase II Metabolizing Enzyme UDP-Glucuronosyltransferase 2B10
分子名称: SULFATE ION, UDP-glucuronosyltransferase 2B10
著者Yin, X.L, Tong, J.S.
登録日2022-07-07
公開日2023-07-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.527 Å)
主引用文献Crystal Structure Determination of Nucleotide-sugar Binding Domain of Human UDP-glucuronosyltransferases 2B10.
Protein Pept.Lett., 30, 2023
3TZ2
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BU of 3tz2 by Molmil
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/phenylbutyrate complex
分子名称: 4-PHENYL-BUTANOIC ACID, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
著者Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T.
登録日2011-09-26
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
5XYZ
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BU of 5xyz by Molmil
The structure of human BTK kinase domain in complex with a covalent inhibitor
分子名称: N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide, Tyrosine-protein kinase BTK
著者Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Xie, Y.T, Li, L, Qi, X.B, Huang, N.
登録日2017-07-11
公開日2018-05-23
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery.
J. Med. Chem., 60, 2017
3TZ4
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BU of 3tz4 by Molmil
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex with ADP
分子名称: (2S)-2-chloro-4-methylpentanoic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T.
登録日2011-09-27
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
5XYX
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BU of 5xyx by Molmil
The structure of p38 alpha in complex with a triazol inhibitor
分子名称: Mitogen-activated protein kinase 14, N-(2-chloro-6-fluorobenzyl)-5-(furan-2-yl)-2H-1,2,4-triazol-3-amine
著者Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Li, L, Qi, X.B, Huang, N.
登録日2017-07-11
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery.
J. Med. Chem., 60, 2017
5XYY
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BU of 5xyy by Molmil
The structure of p38 alpha in complex with a triazol inhibitor
分子名称: 3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-4H-1,2,4-triazol-3-yl)phenol, Mitogen-activated protein kinase 14
著者Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Li, L, Qi, X.B, Huang, N.
登録日2017-07-11
公開日2018-01-17
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery.
J. Med. Chem., 60, 2017
3TZ0
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BU of 3tz0 by Molmil
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex
分子名称: (2S)-2-chloro-4-methylpentanoic acid, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
著者Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T.
登録日2011-09-26
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
3TZ5
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BU of 3tz5 by Molmil
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/phenylbutyrate complex with ADP
分子名称: 4-PHENYL-BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T.
登録日2011-09-27
公開日2012-10-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
4XHR
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BU of 4xhr by Molmil
Structure of a phospholipid trafficking complex, native
分子名称: Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial
著者Yu, F, He, F, Wang, C, Zhang, P.
登録日2015-01-06
公開日2015-07-01
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex
Embo Rep., 16, 2015
4XIZ
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BU of 4xiz by Molmil
Structure of a phospholipid trafficking complex with substrate
分子名称: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Mitochondrial distribution and morphology protein 35, Protein UPS1, ...
著者Yu, F, He, F, Wang, C, Zhang, P.
登録日2015-01-08
公開日2015-07-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex
Embo Rep., 16, 2015
4YMR
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BU of 4ymr by Molmil
Crystal structure of the domain swapped PXB/TPR domain of mouse SNX21
分子名称: Protein Snx21
著者Collins, B.C, Teasdale, R.D, Clairfeuille, T.
登録日2015-03-07
公開日2015-04-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and Membrane Binding Properties of the Endosomal Tetratricopeptide Repeat (TPR) Domain-containing Sorting Nexins SNX20 and SNX21.
J.Biol.Chem., 290, 2015
5AZF
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BU of 5azf by Molmil
Crystal structure of LGG-1 complexed with a WEEL peptide
分子名称: CADMIUM ION, Protein lgg-1, SULFATE ION, ...
著者Watanabe, Y, Noda, N.N.
登録日2015-10-05
公開日2015-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
Mol.Cell, 60, 2015
5AZG
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BU of 5azg by Molmil
Crystal structure of LGG-1 complexed with a UNC-51 peptide
分子名称: CADMIUM ION, Protein lgg-1, Serine/threonine-protein kinase unc-51
著者Watanabe, Y, Fujioka, Y, Noda, N.N.
登録日2015-10-05
公開日2015-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
Mol.Cell, 60, 2015
5AZH
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BU of 5azh by Molmil
Crystal structure of LGG-2 fused with an EEEWEEL peptide
分子名称: EEEWEEL peptide,Protein lgg-2, MAGNESIUM ION
著者Watanabe, Y, Fujioka, Y, Noda, N.N.
登録日2015-10-05
公開日2015-12-30
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
Mol.Cell, 60, 2015
5XXY
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BU of 5xxy by Molmil
Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A
分子名称: Programmed cell death 1 ligand 1, heavy chain of atezolizumab fab, light chain of atezolizumab fab
著者Zhou, A, Zhang, F.
登録日2017-07-05
公開日2017-09-20
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab.
Oncotarget, 8, 2017
6KMH
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BU of 6kmh by Molmil
The crystal structure of CASK/Mint1 complex
分子名称: Amyloid-beta A4 precursor protein-binding family A member 1, CHLORIDE ION, IODIDE ION, ...
著者Li, W, Feng, W.
登録日2019-07-31
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion.
Cell Discov, 6, 2020
4QKB
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BU of 4qkb by Molmil
Crystal structure of seleno-methionine labelled human ALKBH7 in complex with alpha-ketoglutarate and Mn(II)
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial, ...
著者Wang, G, He, Q, Chen, Z.
登録日2014-06-05
公開日2014-08-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism
J.Biol.Chem., 289, 2014
4QKD
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BU of 4qkd by Molmil
Crystal structure of human ALKBH7 in complex with alpha-ketoglutarate and Mn(II)
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial, ...
著者Wang, G, Chen, Z.
登録日2014-06-06
公開日2014-08-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism
J.Biol.Chem., 289, 2014

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