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2H77
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Crystal structure of human TR alpha bound T3 in monoclinic space group
分子名称: 3,5,3'TRIIODOTHYRONINE, THRA protein
著者Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I.
登録日2006-06-01
公開日2006-07-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
2H79
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Crystal Structure of human TR alpha bound T3 in orthorhombic space group
分子名称: 3,5,3'TRIIODOTHYRONINE, THRA protein
著者Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I.
登録日2006-06-01
公開日2006-07-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
3CFQ
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BU of 3cfq by Molmil
Crystal structure of human wild-type transthyretin in complex with diclofenac
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, Transthyretin
著者Lima, L.-M.T.R, Foguel, D, Polikarpov, I.
登録日2008-03-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18, 2010
6XOF
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BU of 6xof by Molmil
Crystal structure of SCLam, a non-specific endo-beta-1,3(4)-glucanase from family GH16
分子名称: CALCIUM ION, GH16 family protein, GLYCEROL
著者Liberato, M.V, Bernardes, A, Polikarpov, I, Squina, F.
登録日2020-07-07
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
1GMZ
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BU of 1gmz by Molmil
Crystal structure of the D49 phospholipase A2 piratoxin III from Bothrops pirajai.
分子名称: ISOPROPYL ALCOHOL, PHOSPHOLIPASE A2
著者Rigden, D.J, Lee, W.H, Polikarpov, I.
登録日2001-09-27
公開日2001-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of the D49 Phospholipase A2 Piratoxin III from Bothrops Pirajai Reveals Unprecedented Structural Displacement of the Calcium-Binding Loop: Possible Relationship to Cooperative Substrate Binding
Acta Crystallogr.,Sect.D, 59, 2003
1GQN
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BU of 1gqn by Molmil
Native 3-dehydroquinase from Salmonella typhi
分子名称: 3-DEHYDROQUINATE DEHYDRATASE
著者Lee, W.-H, Perles, L.A, Nagem, R.A.P, Polikarpov, I, Sawyer, L.
登録日2001-11-26
公開日2003-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Comparison of Different Crystal Forms of 3-Dehydroquinase from Salmonella Typhi and its Implications for Enzyme Activity
Acta Crystallogr.,Sect.D, 58, 2002
1HWU
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BU of 1hwu by Molmil
STRUCTURE OF PII PROTEIN FROM HERBASPIRILLUM SEROPEDICAE
分子名称: PII PROTEIN
著者Benelli, E.M, Buck, M, Polikarpov, I, De Souza, E.M, Cruz, L.M, Pedrosa, F.O.
登録日2001-01-10
公開日2003-06-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK.
Eur.J.Biochem., 269, 2002
2RC5
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BU of 2rc5 by Molmil
Refined structure of FNR from Leptospira interrogans
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase, SULFATE ION, ...
著者Nascimento, A.S, Catalano-Dupuy, D.L, Polikarpov, I, Ceccarelli, E.A.
登録日2007-09-19
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.431 Å)
主引用文献Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.
Bmc Struct.Biol., 7, 2007
1QFE
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BU of 1qfe by Molmil
THE STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE FROM SALMONELLA TYPHI
分子名称: 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, PROTEIN (3-DEHYDROQUINATE DEHYDRATASE)
著者Shrive, A.K, Polikarpov, I, Sawyer, L, Coggins, J.R, Hawkins, A.R.
登録日1999-04-05
公開日2000-04-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Nat.Struct.Biol., 6, 1999
1QG5
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BU of 1qg5 by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORM A)
分子名称: BETA-LACTOGLOBULIN
著者Oliveira, K.M.G, Sawyer, L, Polikarpov, I.
登録日1999-04-20
公開日2001-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C222(1). Structural differences between genetic variants A and B and features of the Tanford transition.
Eur.J.Biochem., 268, 2001
1QLL
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BU of 1qll by Molmil
Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai
分子名称: N-TRIDECANOIC ACID, PHOSPHOLIPASE A2
著者Lee, W.-H, Polikarpov, I.
登録日1999-09-01
公開日2000-09-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid
Biochemistry, 40, 2001
3NEX
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BU of 3nex by Molmil
V30M mutant human transthyretin (TTR) complexed with GC-24 (V30M:GC-24)
分子名称: GLYCEROL, Transthyretin, [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID
著者Trivella, D.B.B, Polikarpov, I.
登録日2010-06-09
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
1L9W
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BU of 1l9w by Molmil
CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT
分子名称: 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, 3-dehydroquinate dehydratase aroD
著者Lee, W.H, Perles, L.A, Nagem, R.A.P, Shrive, A.K, Hawkins, A, Sawyer, L, Polikarpov, I.
登録日2002-03-26
公開日2003-03-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity.
Acta Crystallogr.,Sect.D, 58, 2002
3NES
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BU of 3nes by Molmil
V30M mutant human transthyretin (TTR) complexed with GC-1 (V30M:GC-1)
分子名称: GLYCEROL, Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Trivella, D.B.B, Polikarpov, I.
登録日2010-06-09
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
3NEO
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BU of 3neo by Molmil
Wild type human transthyretin (TTR) complexed with GC-24 (TTRwt:GC-24)
分子名称: Transthyretin, [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID
著者Trivella, D.B.B, Polikarpov, I.
登録日2010-06-09
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
1B8E
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BU of 1b8e by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE BOVINE BETA-LACTOGLOBULIN (ISOFORMS A AND B) IN ORTHOROMBIC SPACE GROUP
分子名称: PROTEIN (BETA-LACTOGLOBULIN)
著者Oliveira, K.M.G, Sawyer, L, Polikarpov, I.
登録日1999-01-30
公開日2001-05-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of bovine beta-lactoglobulin in the orthorhombic space group C222(1). Structural differences between genetic variants A and B and features of the Tanford transition.
Eur.J.Biochem., 268, 2001
1DN0
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BU of 1dn0 by Molmil
STRUCTURE OF THE FAB FRAGMENT FROM A HUMAN IGM COLD AGGLUTININ
分子名称: IGM-KAPPA COLD AGGLUTININ (HEAVY CHAIN), IGM-KAPPA COLD AGGLUTININ (LIGHT CHAIN)
著者Cauerhff, A, Braden, B, Carvalho, J.G, Leoni, J, Polikarpov, I, Goldbaum, F.
登録日1999-12-15
公開日2001-01-24
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Three-dimensional structure of the Fab from a human IgM cold agglutinin.
J.Immunol., 165, 2000
3ILN
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BU of 3iln by Molmil
X-ray structure of the laminarinase from Rhodothermus marinus
分子名称: CALCIUM ION, GLYCEROL, Laminarinase
著者Bleicher, L, Golubev, A, Rojas, A.L, Nascimento, A.S, Polikarpov, I.
登録日2009-08-07
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations.
J.Phys.Chem.B, 115, 2011
3KGU
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BU of 3kgu by Molmil
Wild type human transthyretin (TTR) complexed with genistein (TTRwt:GEN) pH 7.5
分子名称: GENISTEIN, Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3KGT
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BU of 3kgt by Molmil
V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5
分子名称: GENISTEIN, Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3HZF
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BU of 3hzf by Molmil
Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group
分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid
著者Aparicio, R, Bleicher, L, Polikarpov, I.
登録日2009-06-23
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
3I36
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BU of 3i36 by Molmil
Crystal Structure of Rat Protein Tyrosine Phosphatase eta Catalytic Domain
分子名称: CHLORIDE ION, Vascular protein tyrosine phosphatase 1
著者Nascimento, A.S, Matozo, H.C, Santos, M.A, Polikarpov, I.
登録日2009-06-30
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.841 Å)
主引用文献To be Published
To be Published
3KGS
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BU of 3kgs by Molmil
V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5
分子名称: Transthyretin
著者Trivella, D.B, Polikarpov, I.
登録日2009-10-29
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
3G9V
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BU of 3g9v by Molmil
Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
分子名称: Interleukin 22 receptor, alpha 2, Interleukin-22
著者de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I.
登録日2009-02-14
公開日2009-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.756 Å)
主引用文献Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
FEBS Lett., 583, 2009
3DLQ
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Crystal structure of the IL-22/IL-22R1 complex
分子名称: Interleukin-22, Interleukin-22 receptor subunit alpha-1
著者Bleicher, L, de Moura, P.R, Watanabe, L, Colau, D, Dumoutier, L, Renauld, J.-C, Polikarpov, I.
登録日2008-06-28
公開日2008-08-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism
Febs Lett., 582, 2008

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