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SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.08 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDG

SARS-CoV-2 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.01 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDL

SARS-CoV-2 D614G 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (2.96 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KE8

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2022-02-02
実験手法	ELECTRON MICROSCOPY (3.26 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDJ

SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer fully cleaved by furin without the P986-P987 stabilizing mutations (S-RRAR-D614G)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.49 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KE4

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-class)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.21 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KDK

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-08
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (2.8 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7LWU

UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.22 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWV

UK (B.1.1.7) SARS-CoV-2 spike protein variant (S-GSAS-B.1.1.7) in the 1-RBD-up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.12 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7KEC

SARS-CoV-2 D614G 1-RBD-up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-Classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.84 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7LWQ

Mink Cluster 5-associated SARS-CoV-2 spike protein(S-GSAS-D614G-delFV) missing the S1 subunit and SD2 subdomain of one protomer
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.44 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWL

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.84 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWK

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 3-RBD down conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.92 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7LWP

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 2-RBD up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.01 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

7KE7

SARS-CoV-2 D614G 3-RBD-down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G Sub-Classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.32 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7KE6

SARS-CoV-2 D614G 3 RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-D614G sub-classification)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2020-10-10
公開日	2020-11-04
最終更新日	2021-03-31
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction. Cell Rep, 34, 2021

7LWN

Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者	Gobeil, S, Acharya, P.
登録日	2021-03-01
公開日	2021-03-31
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.94 Å)
主引用文献	Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity. Science, 373, 2021

8DTK

Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
著者	May, A.J, Manne, K, Acharya, P.
登録日	2022-07-25
公開日	2023-08-02
最終更新日	2024-02-28
実験手法	ELECTRON MICROSCOPY (3.77 Å)
主引用文献	Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates. Biorxiv, 2023

8U1D

Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env Local Refinement
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH1285 Heavy Chain, DH1285 Light Chain, ...
著者	Thakur, B, Stalls, V.D, Acharya, P.
登録日	2023-08-31
公開日	2024-01-03
最終更新日	2024-07-17
実験手法	ELECTRON MICROSCOPY (4.25 Å)
主引用文献	Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques. Cell, 187, 2024

8F5I

SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1
分子名称:	DH1057.1 HC, DH1057.1 LC, Specialized acyl carrier protein, ...
著者	Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
登録日	2022-11-14
公開日	2023-10-11
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nat Commun, 14, 2023

8F5H

SARS-CoV-2 S2 helix epitope scaffold
分子名称:	S2hlx_EX_19
著者	Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
登録日	2022-11-14
公開日	2023-10-11
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nat Commun, 14, 2023

8FDO

SARS-CoV-2 fusion peptide epitope scaffold FP15 bound to DH1058
分子名称:	DH1058 Heavy chain, DH1058 Light chain, FP15
著者	Kapingidza, A.B, Marston, D.J, Wrapp, D, Winters, K, Azoitei, M.L.
登録日	2022-12-04
公開日	2023-10-11
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Engineered immunogens to elicit antibodies against conserved coronavirus epitopes. Nat Commun, 14, 2023

5KG9

Crystal structure of the gp120 v2 antibody RE505-22 Fab from IGH- and IGK-humanized mouse
分子名称:	Antibody RE505-22 Fab heavy chain, Antibody RE505-22 Fab light chain
著者	Nicely, N.I.
登録日	2016-06-13
公開日	2017-01-25
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice. J. Immunol., 198, 2017

6V8Z

VRC03 and 10-1074 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure
分子名称:	10-1074 Fab Heavy Chain, 10-1074 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Henderson, R, Acharya, P.
登録日	2019-12-12
公開日	2020-02-05
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. Nat Commun, 11, 2020

6V8X

VRC01 Bound BG505 F14 HIV-1 SOSIP Envelope Trimer Structure
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者	Henderson, R, Acharya, P.
登録日	2019-12-12
公開日	2020-02-05
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. Nat Commun, 11, 2020

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