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6XSN
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BU of 6xsn by Molmil
Crystal structure of NHP VD20.5A4 Fab in complex with 16055 V1V2 1FD6 scaffold
分子名称: 1,2-ETHANEDIOL, 16055_V1V2-1FD6, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Aljedani, S, Pancera, M.
登録日2020-07-15
公開日2021-07-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
Plos Pathog., 17, 2021
6OL5
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BU of 6ol5 by Molmil
Structure of iglb12 Fab in complex with anti-idiotype ib3 Fab
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
著者Weidle, C, Pancera, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6OL7
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BU of 6ol7 by Molmil
Crystal structure of glVRC01 scFv in complex with anti-idiotype iv8 scFv
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Weidle, C, Pancera, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.419 Å)
主引用文献Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
J.Exp.Med., 216, 2019
8V99
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BU of 8v99 by Molmil
GII.26 Leon 4509 norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Capsid protein VP1, ...
著者Kher, G, Reese, T, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V98
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BU of 8v98 by Molmil
GII.24 Loreto 1972 norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Capsid protein VP1
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V9A
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BU of 8v9a by Molmil
GII.NA1 Loreto 1257 norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1
著者Kher, G, Kim, I, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V97
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BU of 8v97 by Molmil
GII.17 CS-E1 norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1, DI(HYDROXYETHYL)ETHER
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V95
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BU of 8v95 by Molmil
GII.8 Amsterdam norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein (Fragment)
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V96
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BU of 8v96 by Molmil
GII.14 M7 norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8VRV
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BU of 8vrv by Molmil
GII.4c H2-tri HBGA norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID, ...
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2024-01-22
公開日2024-06-19
最終更新日2025-01-01
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8VRU
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BU of 8vru by Molmil
GII.4c apo norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein, FORMIC ACID
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2024-01-22
公開日2024-06-19
最終更新日2025-01-01
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8EN4
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BU of 8en4 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 53
分子名称: 1,2-ETHANEDIOL, Nanobody 53, VP1
著者Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN5
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BU of 8en5 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 56
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GII.4 P domain, ...
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EMZ
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BU of 8emz by Molmil
Structure of GII.17 norovirus in complex with Nanobody 2
分子名称: 1,2-ETHANEDIOL, GII.17 P domain, Nanobody 2
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN1
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BU of 8en1 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 30
分子名称: GII.4 P domain, Nanobody 30
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EMY
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BU of 8emy by Molmil
Structure of GII.4 norovirus in complex with Nanobody 82
分子名称: 1,2-ETHANEDIOL, GII.4 P domain, Nanobody 82
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN2
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BU of 8en2 by Molmil
Structure of GII.10 norovirus in complex with Nanobody 34
分子名称: 1,2-ETHANEDIOL, GII.10 P domain, Nanobody 34
著者Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN3
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BU of 8en3 by Molmil
Structure of GII.17 norovirus in complex with Nanobody 45
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1, Nanobody 45
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN0
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BU of 8en0 by Molmil
Structure of GII.17 norovirus in complex with Nanobody 7
分子名称: Capsid protein VP1, Nanobody 7
著者Kher, G, Sabin, C, Koromyslova, A, Pancera, M, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
8EN6
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BU of 8en6 by Molmil
Structure of GII.4 norovirus in complex with Nanobody 76
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GII.4 P domain, ...
著者Kher, G, Sabin, C, Pancera, M, Koromyslova, A, Hansman, G.
登録日2022-09-28
公開日2023-03-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies.
J.Virol., 97, 2023
7RAQ
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BU of 7raq by Molmil
Crystal structure of CV3-25 Fab bound to SARS-CoV-2 spike stem helix peptide
分子名称: CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, GLYCEROL, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-07-02
公開日2022-04-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
Commun Biol, 5, 2022
7RDW
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BU of 7rdw by Molmil
Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2021-07-12
公開日2022-05-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.
Sci Adv, 8, 2022
7U61
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BU of 7u61 by Molmil
Crystal Structure of Anti-Nicotine Antibody NIC311 Fab Complexed with Nicotine
分子名称: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, NIC311 Fab Heavy Chain, NIC311 Fab Light Chain, ...
著者Rodarte, J.V, Pancera, M.P, Liban, T.L.
登録日2022-03-03
公開日2023-01-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
7U64
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BU of 7u64 by Molmil
Crystal Structure of Anti-Fentanyl Antibody HY6-F9.6 Fab Complexed with Fentanyl
分子名称: ACETATE ION, HY6-F9.6 Fab heavy chain, HY6-F9.6 Fab light chain, ...
著者Rodarte, J.V, Pancera, M.P.
登録日2022-03-03
公開日2023-01-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
7U62
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BU of 7u62 by Molmil
Crystal structure of Anti-Heroin Antibody HY4-1F9 Fab Complexed with Morphine
分子名称: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, ACETATE ION, HY4-1F9 Fab Heavy Chain, ...
著者Rodarte, J.V, Pancera, M.P.
登録日2022-03-03
公開日2023-01-11
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023

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