6CNO
 
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6CNM
 | | Cryo-EM structure of the human SK4/calmodulin channel complex | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calmodulin-1, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Lee, C.H, MacKinnon, R. | | 登録日 | 2018-03-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
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6COZ
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1N9P
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8EP1
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8EOW
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8EP0
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7S5Y
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | 著者 | Zhao, C, MacKinnon, R. | | 登録日 | 2021-09-12 | | 公開日 | 2021-12-01 | | 最終更新日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Z
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | 著者 | Zhao, C, MacKinnon, R. | | 登録日 | 2021-09-12 | | 公開日 | 2021-12-01 | | 最終更新日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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1OTU
 | | Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex | | 分子名称: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | 著者 | Dutzler, R, Campbell, E.B, MacKinnon, R. | | 登録日 | 2003-03-23 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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6V3G
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6UQF
 | | Human HCN1 channel in a hyperpolarized conformation | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Lee, C.-H, MacKinnon, R. | | 登録日 | 2019-10-19 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
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6UQG
 | | Human HCN1 channel Y289D mutant | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | | 著者 | Lee, C.-H, MacKinnon, R. | | 登録日 | 2019-10-19 | | 公開日 | 2019-12-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
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6V35
 | | Cryo-EM structure of Ca2+-free hsSlo1-beta4 channel complex | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Tao, X, MacKinnon, R. | | 登録日 | 2019-11-25 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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6V22
 | | Cryo-EM structure of Ca2+-bound hsSlo1-beta4 channel complex | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Tao, X, MacKinnon, R. | | 登録日 | 2019-11-22 | | 公開日 | 2019-12-25 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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1OTT
 | | Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex | | 分子名称: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | 著者 | Dutzler, R, Campbell, E.B, MacKinnon, R. | | 登録日 | 2003-03-23 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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6V38
 | | Cryo-EM structure of Ca2+-bound hsSlo1 channel | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ... | | 著者 | Tao, X, MacKinnon, R. | | 登録日 | 2019-11-25 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
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6UWM
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1OTS
 | | Structure of the Escherichia coli ClC Chloride channel and Fab Complex | | 分子名称: | CHLORIDE ION, Fab fragment (heavy chain), Fab fragment (light chain), ... | | 著者 | Dutzler, R, Campbell, E.B, MacKinnon, R. | | 登録日 | 2003-03-22 | | 公開日 | 2003-04-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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4JTD
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | | 著者 | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | | 登録日 | 2013-03-23 | | 公開日 | 2013-06-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
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4JTC
 | | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ | | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | | 登録日 | 2013-03-23 | | 公開日 | 2013-06-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
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4KFM
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4I9W
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8ED7
 | | cryo-EM structure of TRPM3 ion channel in apo state | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, Transient receptor potential cation channel, subfamily M, ... | | 著者 | Zhao, C, MacKinnon, R. | | 登録日 | 2022-09-03 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
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8ED8
 | | cryo-EM structure of TRPM3 ion channel in the presence of PIP2 and PregS, state 1 | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | | 著者 | Zhao, C, MacKinnon, R. | | 登録日 | 2022-09-03 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
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