8ED8
cryo-EM structure of TRPM3 ion channel in the presence of PIP2 and PregS, state 1
Summary for 8ED8
Entry DOI | 10.2210/pdb8ed8/pdb |
Related | 8DDQ 8DDR 8DDS 8DDT 8DDU 8DDV 8DDW 8DDX 8ED7 |
EMDB information | 28032 |
Descriptor | Transient receptor potential cation channel, subfamily M, member 3, Unidentified segment at the N-terminus of TRPM3, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... (6 entities in total) |
Functional Keywords | trpm3, ion channel, pip2, membrane protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 632989.72 |
Authors | Zhao, C.,MacKinnon, R. (deposition date: 2022-09-03, release date: 2022-11-02, Last modification date: 2023-01-18) |
Primary citation | Zhao, C.,MacKinnon, R. Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111:81-, 2023 Cited by PubMed: 36283409DOI: 10.1016/j.neuron.2022.10.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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