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8ED8

cryo-EM structure of TRPM3 ion channel in the presence of PIP2 and PregS, state 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel, subfamily M, member 3polymer1344154780.54UniProt (Q5F4S7)
Pfam (PF18139)
Pfam (PF00520)
Pfam (PF16519)
In PDB
Mus musculus (house mouse)
2E, F, G, HUnidentified segment at the N-terminus of TRPM3polymer171464.84Mus musculus
3A, B, C, D1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATEnon-polymer705.04Chemie (3PH)
4A, B, C, D(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-ennon-polymer544.84Chemie (9Z9)
5A, B, C, D[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.64Chemie (PIO)
6ASODIUM IONnon-polymer23.01Chemie (NA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight624981.3
Non-Polymers*Number of molecules13
Total formula weight8008.5
All*Total formula weight632989.7
*Water molecules are not included.

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PDB entries from 2024-04-24

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