1QWN
 
 | | GOLGI ALPHA-MANNOSIDASE II Covalent Intermediate Complex with 5-fluoro-gulosyl-fluoride | | 分子名称: | (2R,3S,4R,5S)-2,6-difluoro-2-(hydroxymethyl)oxane-3,4,5-triol, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Numao, S, Kuntz, D.A, Withers, S.G, Rose, D.R. | | 登録日 | 2003-09-02 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates.
J.Biol.Chem., 278, 2003
|
|
1HXK
 | | GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R. | | 登録日 | 2001-01-16 | | 公開日 | 2002-01-16 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
|
|
1HWW
 | | GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R. | | 登録日 | 2001-01-10 | | 公開日 | 2002-01-10 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
|
|
1HTY
 | | GOLGI ALPHA-MANNOSIDASE II | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R. | | 登録日 | 2001-01-02 | | 公開日 | 2002-01-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
|
|
1QX1
 | | Golgi alpha-mannosidase II D341N mutant complex with 2-F-mannosyl-F | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-fluoro-beta-D-mannopyranosyl fluoride, ... | | 著者 | Numao, S, Kuntz, D.A, Withers, S.G, Rose, D.R. | | 登録日 | 2003-09-04 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates.
J.Biol.Chem., 278, 2003
|
|
1QWU
 | | Golgi alpha-mannosidase II D341N mutant complex with 5-F-guloside | | 分子名称: | (2R,3S,4R,5S)-2,6-difluoro-2-(hydroxymethyl)oxane-3,4,5-triol, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Numao, S, Kuntz, D.A, Withers, S.G, Rose, D.R. | | 登録日 | 2003-09-03 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Insights into the mechanism of Drosophila melanogaster Golgi alpha-mannosidase II through the structural analysis of covalent reaction intermediates.
J.Biol.Chem., 278, 2003
|
|
7SCW
 | | KRAS full length wild-type in complex with RGL1 Ras association domain | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | | 著者 | Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B. | | 登録日 | 2021-09-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J.Mol.Biol., 434, 2022
|
|
7SCX
 | | KRAS full-length G12V in complex with RGL1 Ras association domain | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | | 著者 | Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B. | | 登録日 | 2021-09-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J.Mol.Biol., 434, 2022
|
|
3CV5
 | | GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with 3alpha,6alpha-mannopentaose | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-mannosidase 2, ... | | 著者 | Shah, N, Kuntz, D.A, Rose, D.R. | | 登録日 | 2008-04-17 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Golgi alpha-mannosidase II cleaves two sugars sequentially in the same catalytic site.
Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
7RV5
 | |
7RV3
 | |
7RV8
 | | Crystal structure of the BCL6 BTB domain in complex with OICR-10268 | | 分子名称: | DIMETHYL SULFOXIDE, Isoform 2 of B-cell lymphoma 6 protein, N-[5-chloro-2-(morpholin-4-yl)pyridin-4-yl]-2-{5-(3-cyano-4-hydroxy-5-methylphenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide | | 著者 | Kuntz, D.A, Prive, G.G. | | 登録日 | 2021-08-18 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structure of the BCL6 BTB domain
To Be Published
|
|
7RV9
 | | Crystal structure of the BCL6 BTB domain in complex with OICR-10269 | | 分子名称: | DIMETHYL SULFOXIDE, Isoform 2 of B-cell lymphoma 6 protein, N-[5-chloro-2-(4-methylpiperazin-1-yl)pyridin-4-yl]-2-{5-(3-cyano-4-hydroxy-5-methylphenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide | | 著者 | Kuntz, D.A, Prive, G.G. | | 登録日 | 2021-08-18 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the BCL6 BTB domain
To Be Published
|
|
7RV7
 | |
7RV4
 | |
7RV6
 | |
7RV0
 | |
7RV2
 | |
7RUX
 | |
7RUW
 | |
7RUZ
 | |
7RV1
 | | Crystal structure of the BCL6 BTB domain in complex with OICR-8826 | | 分子名称: | (E)-3-(7-(2-((3-chloropyridin-4-yl)amino)-2-oxoethyl)-3-(3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)acrylamide, B-cell lymphoma 6 protein, DIMETHYL SULFOXIDE, ... | | 著者 | Kuntz, D.A, Prive, G.G. | | 登録日 | 2021-08-18 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Crystal structure of the BCL6 BTB domain in complex with OICR-8826
To Be Published
|
|
7RUY
 | |
3CZN
 | | Golgi alpha-mannosidase II (D204A nucleophile mutant) in complex with GnMan5Gn | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Alpha-mannosidase 2, ... | | 著者 | Shah, N, Rose, D.R. | | 登録日 | 2008-04-29 | | 公開日 | 2008-06-24 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Golgi alpha-mannosidase II cleaves two sugars sequentially in the same catalytic site.
Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
2AP2
 | |
