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1YIW
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BU of 1yiw by Molmil
X-ray Crystal Structure of a Chemically Synthesized Ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, Ubiquitin
著者Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-01-13
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
1YJ1
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BU of 1yj1 by Molmil
X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, Ubiquitin
著者Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-01-13
公開日2005-06-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
1Y3T
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BU of 1y3t by Molmil
Crystal structure of YxaG, a dioxygenase from Bacillus subtilis
分子名称: FE (III) ION, Hypothetical protein yxaG
著者Gopal, B, Madan, L.L, Betz, S.F, Kossiakoff, A.A.
登録日2004-11-26
公開日2005-01-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of a Quercetin 2,3-Dioxygenase from Bacillus subtilis Suggests Modulation of Enzyme Activity by a Change in the Metal Ion at the Active Site(s)
Biochemistry, 44, 2005
1Z7C
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BU of 1z7c by Molmil
Crystal Structure of Human Placental Lactogen
分子名称: Chorionic somatomammotropin hormone
著者Walsh, S.T.R, Kossiakoff, A.A.
登録日2005-03-24
公開日2006-03-07
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen.
J.Mol.Biol., 358, 2006
1FVC
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BU of 1fvc by Molmil
X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING
分子名称: IGG1-KAPPA 4D5 FV (HEAVY CHAIN), IGG1-KAPPA 4D5 FV (LIGHT CHAIN)
著者Eigenbrot, C, Randal, M, Kossiakoff, A.A, Presta, L.
登録日1992-10-20
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
J.Mol.Biol., 229, 1993
1HUW
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BU of 1huw by Molmil
THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION
分子名称: HUMAN GROWTH HORMONE
著者Ultsch, M.H, Somers, W.S, Kossiakoff, A.A, De Vos, A.M.
登録日1993-09-22
公開日1994-01-31
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of affinity-matured human growth hormone at 2 A resolution.
J.Mol.Biol., 236, 1994
1FVD
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BU of 1fvd by Molmil
X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING
分子名称: IGG1-KAPPA 4D5 FAB (HEAVY CHAIN), IGG1-KAPPA 4D5 FAB (LIGHT CHAIN)
著者Eigenbrot, C, Presta, L, Randal, M, Kossiakoff, A.A.
登録日1992-10-20
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
J.Mol.Biol., 229, 1993
3IVK
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BU of 3ivk by Molmil
Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment
分子名称: CADMIUM ION, CHLORIDE ION, Fab heavy chain, ...
著者Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A.
登録日2009-09-01
公開日2010-03-02
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
1FVE
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BU of 1fve by Molmil
X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING
分子名称: IGG1-KAPPA 4D5 FAB (HEAVY CHAIN), IGG1-KAPPA 4D5 FAB (LIGHT CHAIN)
著者Eigenbrot, C, Randal, M, Presta, L, Kossiakoff, A.A.
登録日1992-10-20
公開日1993-10-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
J.Mol.Biol., 229, 1993
4JQI
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BU of 4jqi by Molmil
Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide
分子名称: 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ...
著者Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J.
登録日2013-03-20
公開日2013-04-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
8T6I
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BU of 8t6i by Molmil
Structure of VHH-Fab complex with engineered Crystal Kappa region
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-16
公開日2023-11-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T58
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BU of 8t58 by Molmil
Structure of VHH-Fab complex with engineered FNQIKG elbow region
分子名称: CHLORIDE ION, Fab heavy chain, Fab light chain, ...
著者Filippova, E.V, Kossiakoff, A.A.
登録日2023-06-12
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T8I
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BU of 8t8i by Molmil
Structure of VHH-Fab complex with engineered Elbow FNQIKG, Crystal Kappa and SER substitutions
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab heavy chain, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-22
公開日2023-11-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T9Y
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BU of 8t9y by Molmil
Structure of VHH-Fab complex with engineered Elbow FNQIKG and Crystal Kappa regions
分子名称: DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain, ...
著者Filippova, E.V, Thompson, I, Kossiakoff, A.A.
登録日2023-06-26
公開日2023-11-29
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8THE
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BU of 8the by Molmil
Cryo-EM structure of Pseudomonas aeruginosa TonB-dependent transporter PhuR in complex with synthetic antibody and heme
分子名称: (2~{R},4~{R},5~{S},6~{S})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{S},5~{R},6~{S})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{R},4~{R},5~{S},6~{S})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{S})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Heme/hemoglobin uptake outer membrane receptor PhuR, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Knejski, P, Erramilli, S.K, Kossiakoff, A.A.
登録日2023-07-15
公開日2024-01-31
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding.
Structure, 32, 2024
6B70
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BU of 6b70 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin
分子名称: FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ...
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-03
公開日2017-12-27
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6AZ2
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BU of 6az2 by Molmil
Crystal structure of Asf1-Fab 12E complex
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A.
登録日2017-09-09
公開日2018-01-10
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.477 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
6AYZ
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BU of 6ayz by Molmil
Crystal structure of Asf1-Fab 12E complex
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A.
登録日2017-09-08
公開日2018-01-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
6B6Z
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BU of 6b6z by Molmil
Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
分子名称: Apo Fab Heavy Chain, Apo Fab Light Chain, ZINC ION
著者Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S.
登録日2017-10-03
公開日2018-12-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.112 Å)
主引用文献Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
6BF8
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BU of 6bf8 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-04-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Y
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BU of 6b7y by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2017-11-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF6
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BU of 6bf6 by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B3Q
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BU of 6b3q by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-09-22
公開日2017-11-22
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BFC
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BU of 6bfc by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2017-12-27
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Z
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BU of 6b7z by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
分子名称: FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2018-01-10
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018

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