6E4A
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![BU of 6e4a by Molmil](/molmil-images/mine/6e4a) | Crystal structure of human BRD4(1) in complex with CN750 | 分子名称: | 5-(4-{[(3-chlorophenyl)methyl]amino}-2-{4-[2-(dimethylamino)ethyl]piperazin-1-yl}quinazolin-6-yl)-1-methylpyridin-2(1H)-one, Bromodomain-containing protein 4, GLYCEROL | 著者 | Fontano, E, White, A, Lakshminarasimhan, D, Suto, R.K. | 登録日 | 2018-07-17 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Discovery and lead identification of quinazoline-based BRD4 inhibitors. Bioorg. Med. Chem. Lett., 28, 2018
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6GXK
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![BU of 6gxk by Molmil](/molmil-images/mine/6gxk) | Crystal structure of Aldo-Keto Reductase 1C3 (AKR1C3) complexed with inhibitor. | 分子名称: | 1,2-ETHANEDIOL, 4-[[1-(4-chlorophenyl)carbonyl-5-methoxy-2-methyl-indol-3-yl]methyl]-1,2,5-oxadiazol-3-one, Aldo-keto reductase family 1 member C3, ... | 著者 | Goyal, P, Wahlgren, W.Y, Friemann, R. | 登録日 | 2018-06-27 | 公開日 | 2019-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3. Acs Med.Chem.Lett., 10, 2019
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6JXN
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![BU of 6jxn by Molmil](/molmil-images/mine/6jxn) | Crystal Structure of Indigo reductase from Bacillus smithii type strain DSM 4216 | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, FLAVIN MONONUCLEOTIDE, ... | 著者 | Yoneda, K, Sakuraba, H, Ohshima, T. | 登録日 | 2019-04-24 | 公開日 | 2020-04-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural and biochemical characterization of an extremely thermostable FMN-dependent NADH-indigo reductase from Bacillus smithii. Int.J.Biol.Macromol., 164, 2020
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6JXS
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![BU of 6jxs by Molmil](/molmil-images/mine/6jxs) | Crystal Structure of Indigo reductase (Y151F) from Bacillus smithii type strain DSM 4216 | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase | 著者 | Yoneda, K, Sakuraba, H, Ohshima, T. | 登録日 | 2019-04-24 | 公開日 | 2020-04-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and biochemical characterization of an extremely thermostable FMN-dependent NADH-indigo reductase from Bacillus smithii. Int.J.Biol.Macromol., 164, 2020
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4MKC
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![BU of 4mkc by Molmil](/molmil-images/mine/4mkc) | Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378 | 分子名称: | 5-chloro-N~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine, ALK tyrosine kinase receptor, GLYCEROL | 著者 | Lee, C.C, Spraggon, G. | 登録日 | 2013-09-04 | 公開日 | 2014-04-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer. Cancer Discov, 4, 2014
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3BRI
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![BU of 3bri by Molmil](/molmil-images/mine/3bri) | Crystal Structure of apo-LC8 | 分子名称: | ACETATE ION, Dynein light chain 1, cytoplasmic, ... | 著者 | Benison, G, Karplus, P.A, Barbar, E, Chiodo, M. | 登録日 | 2007-12-21 | 公開日 | 2008-12-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Interplay of Ligand Binding and Quaternary Structure in the Diverse Interactions of Dynein Light Chain LC8. J.Mol.Biol., 384, 2008
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1WN7
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![BU of 1wn7 by Molmil](/molmil-images/mine/1wn7) | Crystal structure of archaeal family B DNA polymerase mutant | 分子名称: | Family B DNA Polymerase, GLYCEROL, NICKEL (II) ION | 著者 | Kuroita, T, Matsumura, H, Yokota, N, Hashimoto, H, Imanaka, T, Inoue, T, Kai, Y. | 登録日 | 2004-07-28 | 公開日 | 2005-08-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural Mechanism for Coordination of Proofreading and Polymerase Activities in Archaeal DNA Polymerases J.Mol.Biol., 351, 2005
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2VFS
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2VFU
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![BU of 2vfu by Molmil](/molmil-images/mine/2vfu) | |
2VFR
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2VFT
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2VFV
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![BU of 2vfv by Molmil](/molmil-images/mine/2vfv) | Alditol Oxidase from Streptomyces coelicolor A3(2): Complex with Sulphite | 分子名称: | (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, CHLORIDE ION, XYLITOL OXIDASE | 著者 | Forneris, F, Mattevi, A. | 登録日 | 2007-11-05 | 公開日 | 2008-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structural Analysis of the Catalytic Mechanism and Stereoselectivity in Streptomyces Coelicolor Alditol Oxidase. Biochemistry, 47, 2008
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2Y1V
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![BU of 2y1v by Molmil](/molmil-images/mine/2y1v) | Full length structure of RrgB Pilus protein from Streptococcus pneumoniae | 分子名称: | CELL WALL SURFACE ANCHOR FAMILY PROTEIN, NICKEL (II) ION | 著者 | El-Mortaji, L, Contreras-Martel, C, Manzano, C, Vernet, T, Dessen, A, DiGuilmi, A.M. | 登録日 | 2010-12-10 | 公開日 | 2011-11-09 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | The Full-Length Streptococcus Pneumoniae Major Pilin Rrgb Crystallizes in a Fibre-Like Structure, which Presents the D1 Isopeptide Bond and Provides Details on the Mechanism of Pilus Polymerization. Biochem.J., 441, 2012
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2IY6
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![BU of 2iy6 by Molmil](/molmil-images/mine/2iy6) | 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FROM THERMUS WITH BOUND CITRATE | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, ... | 著者 | Inagaki, E, Sakamoto, K, Nishio, M, Yokoyama, S. | 登録日 | 2006-07-13 | 公開日 | 2006-07-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Thermus Thermophilus Delta(1)- Pyrroline-5-Carboxylate Dehydrogenase. J.Mol.Biol., 362, 2006
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2LKI
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![BU of 2lki by Molmil](/molmil-images/mine/2lki) | Solution NMR structure of holo acyl carrier protein NE2163 from nitrosomonas europaea. Northeast structural genomics consortium target NET1. | 分子名称: | 4'-PHOSPHOPANTETHEINE, Putative uncharacterized protein | 著者 | Lemak, A, Srisailam, S, Lukin, J, Yee, A, Montecchio, M, Semesi, A, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-10-11 | 公開日 | 2011-11-16 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of acyl carrier protein from Nitrosomonas Europaea Proteins, 64, 2006
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3GFJ
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3GFL
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3GF2
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3GEZ
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3GFI
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![BU of 3gfi by Molmil](/molmil-images/mine/3gfi) | Crystal structure of ST1710 complexed with its promoter DNA | 分子名称: | 146aa long hypothetical transcriptional regulator, 5'-D(*TP*AP*AP*CP*AP*AP*TP*AP*GP*CP*AP*AP*A)-3', 5'-D(*TP*TP*GP*CP*TP*AP*TP*TP*GP*T)-3' | 著者 | Kumarevel, T, Tanaka, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2009-02-26 | 公開日 | 2009-08-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | ST1710-DNA complex crystal structure reveals the DNA binding mechanism of the MarR family of regulators. Nucleic Acids Res., 37, 2009
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3GFM
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