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2Y59
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Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein
分子名称: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ...
著者Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P.
登録日2011-01-12
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
2Y55
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Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein
分子名称: ACETONE, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ...
著者Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P.
登録日2011-01-12
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein.
J.Am.Chem.Soc., 133, 2011
1ESU
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BU of 1esu by Molmil
S235A MUTANT OF TEM1 BETA-LACTAMASE
分子名称: BETA-LACTAMASE, SULFATE ION
著者Fonze, E, Charlier, P.
登録日2000-04-11
公開日2000-05-03
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant.
Acta Crystallogr.,Sect.D, 51, 1995
1ES4
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BU of 1es4 by Molmil
C98N mutant of streptomyces K15 DD-transpeptidase
分子名称: DD-TRANSPEPTIDASE
著者Fonze, E, Charlier, P.
登録日2000-04-07
公開日2000-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
Biochemistry, 42, 2003
1ES2
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S96A mutant of streptomyces K15 DD-transpeptidase
分子名称: DD-TRANSPEPTIDASE
著者Fonze, E, Charlier, P.
登録日2000-04-07
公開日2000-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
Biochemistry, 42, 2003
1ES3
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C98A mutant of streptomyces K15 DD-transpeptidase
分子名称: DD-TRANSPEPTIDASE, SODIUM ION
著者Fonze, E, Charlier, P.
登録日2000-04-07
公開日2000-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
Biochemistry, 42, 2003
1IYS
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Crystal Structure of Class A beta-Lactamase Toho-1
分子名称: BETA-LACTAMASE TOHO-1, SULFATE ION
著者Ibuka, A.S, Ishii, Y, Yamaguchi, K, Matsuzawa, H, Sakai, H.
登録日2002-09-06
公開日2003-10-14
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of Extended-Spectrum beta-Lactamase Toho-1: Insights into the Molecular Mechanism for Catalytic Reaction and Substrate Specificity Expansion
Biochemistry, 42, 2003
1HJG
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Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase: The role of arginine-258
分子名称: 3-METHYL-2-OXOBUTANOIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION
著者Lee, H.J, Lloyd, M.D, Clifton, I.J, Harlos, K, Dubus, A, Baldwin, J.E, Frere, J.M, Schofield, C.J.
登録日2001-01-15
公開日2001-06-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1HJF
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Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase: The role of arginine-258
分子名称: 2-OXO-4-METHYLPENTANOIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION
著者Lee, H.J, Lloyd, M.D, Clifton, I.J, Harlos, K, Dubus, A, Baldwin, J.E, Frere, J.M, Schofield, C.J.
登録日2001-01-15
公開日2001-06-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
3GMU
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BU of 3gmu by Molmil
Crystal Structure of Beta-Lactamse Inhibitory Protein (BLIP) in Apo Form
分子名称: AMMONIUM ION, Beta-lactamase inhibitory protein, SULFATE ION
著者Strynadka, N.C.J, Gretes, M, James, M.N.G.
登録日2009-03-15
公開日2009-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Insights into positive and negative requirements for protein-protein interactions by crystallographic analysis of the beta-lactamase inhibitory proteins BLIP, BLIP-I, and BLP.
J.Mol.Biol., 389, 2009
1BLS
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CRYSTALLOGRAPHIC STRUCTURE OF A PHOSPHONATE DERIVATIVE OF THE ENTEROBACTER CLOACAE P99 CEPHALOSPORINASE: MECHANISTIC INTERPRETATION OF A BETA-LACTAMASE TRANSITION STATE ANALOG
分子名称: (P-IODOPHENYLACETYLAMINO)METHYLPHOSPHINIC ACID, BETA-LACTAMASE
著者Knox, J.R, Moews, P.C, Lobkovsky, E.
登録日1993-12-17
公開日1995-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog.
Biochemistry, 33, 1994
1XX2
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BU of 1xx2 by Molmil
Refinement of P99 beta-lactamase from Enterobacter cloacae
分子名称: Beta-lactamase
著者Knox, J.R, Sun, T.
登録日2004-11-03
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog.
Biochemistry, 33, 1994
1W7F
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Crystal structure of the class A beta-lactamase BS3 inhibited with isocitrate
分子名称: BETA-LACTAMASE, ISOCITRIC ACID
著者Petrella, S, Sauvage, E, Herman, R, Charlier, P.
登録日2004-09-01
公開日2006-05-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Class a Beta-Lactamase Bs3 Bs3 Inhibited with Isocitrate
To be Published
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