1ES2

S96A mutant of streptomyces K15 DD-transpeptidase

Summary for 1ES2

Related1SKF 1EQS 1ES3 1ES4 1ES5 1ESI
DescriptorDD-TRANSPEPTIDASE (2 entities in total)
Functional Keywordspenicillin-binding, dd-transpeptidase, serine peptidase, beta-lactamase, hydrolase carboxypeptidase, hydrolase
Biological sourceStreptomyces sp.
Cellular locationSecreted  P39042
Total number of polymer chains1
Total molecular weight27492.32
Authors
Fonze, E.,Charlier, P. (deposition date: 2000-04-07, release date: 2000-05-03, Last modification date: 2017-10-04)
Primary citation
Rhazi, N.,Charlier, P.,Dehareng, D.,Engher, D.,Vermeire, M.,Frere, J.M.,Nguyen-Disteche, M.,Fonze, E.
Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis.
Biochemistry, 42:2895-2906, 2003
PubMed: 12627955 (PDB entries with the same primary citation)
DOI: 10.1021/bi027256x
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.55 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2515 0.8% 3.0% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
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PDB entries from 2020-09-23