6ZPA
| Cyanophage S-2L HD phosphohydrolase (DatZ) bound to dA and one catalytic Zn2+ ion | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, DatZ, LITHIUM ION, ... | 著者 | Czernecki, D, Legrand, P, Delarue, M. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (0.86000258 Å) | 主引用文献 | How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA. Nat Commun, 12, 2021
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6ZPC
| Cyanophage S-2L HD phosphohydrolase (DatZ) bound to dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DatZ, LITHIUM ION, ... | 著者 | Czernecki, D, Legrand, P, Delarue, M. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.2683593 Å) | 主引用文献 | How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA. Nat Commun, 12, 2021
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6ZP9
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6ZPB
| Cyanophage S-2L HD phosphohydrolase (DatZ) bound to dA and two catalytic Co2+ ions | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, COBALT (II) ION, DatZ | 著者 | Czernecki, D, Legrand, P, Delarue, M. | 登録日 | 2020-07-08 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.72097385 Å) | 主引用文献 | How cyanophage S-2L rejects adenine and incorporates 2-aminoadenine to saturate hydrogen bonding in its DNA. Nat Commun, 12, 2021
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5MUR
| X-ray structure of the F14'A mutant of GLIC in complex with propofol | 分子名称: | 2,6-BIS(1-METHYLETHYL)PHENOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Sauguet, L, Fourati, Z, Delarue, M. | 登録日 | 2017-01-13 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels. Cell Rep, 23, 2018
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5MVM
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5MVN
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5MUO
| X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol | 分子名称: | 2,6-BIS(1-METHYLETHYL)PHENOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Fourati, Z, Ruza, R.R, Delarue, M. | 登録日 | 2017-01-13 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels. Cell Rep, 23, 2018
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5MZQ
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5NJY
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5MZR
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5MZT
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5NKJ
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4HFI
| The GLIC pentameric Ligand-Gated Ion Channel at 2.4 A resolution | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Sauguet, L, Corringer, P.J, Delarue, M. | 登録日 | 2012-10-05 | 公開日 | 2013-02-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4ILC
| The GLIC pentameric ligand-gated ion channel in complex with sulfates | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M. | 登録日 | 2012-12-29 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4ILA
| The pentameric ligand-gated ion channel GLIC A237F in complex with Cesium | 分子名称: | ACETATE ION, CESIUM ION, CHLORIDE ION, ... | 著者 | Sauguet, L, Corringer, P.J, Delarue, M. | 登録日 | 2012-12-29 | 公開日 | 2013-02-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4IL9
| The pentameric ligand-gated ion channel GLIC A237F in complex with bromide | 分子名称: | ACETATE ION, BROMIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Sauguet, L, Corringer, P.J, Delarue, M. | 登録日 | 2012-12-29 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4IL4
| The pentameric ligand-gated ion channel GLIC in complex with Se-DDM | 分子名称: | ACETATE ION, CHLORIDE ION, Proton-gated ion channel, ... | 著者 | Sauguet, L, Malherbe, L, Corringer, P.J, Delarue, M. | 登録日 | 2012-12-29 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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4ILB
| The pentameric ligand-gated ion channel GLIC A237F in complex with Rubidium | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Sauguet, L, Corringer, P.J, Delarue, M. | 登録日 | 2012-12-29 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels. Embo J., 32, 2013
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6HMF
| D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) H451 proof-reading deficient variant | 分子名称: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | 著者 | Raia, P, Delarue, M, Sauguet, L. | 登録日 | 2018-09-12 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases. PLoS Biol., 17, 2019
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6GO3
| TdT chimera (Loop1 of pol mu) - apoenzyme | 分子名称: | DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase | 著者 | Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. | 登録日 | 2018-06-01 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
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6GO4
| TdT chimera (Loop1 of pol mu) - binary complex with ddCTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase, MAGNESIUM ION, ... | 著者 | Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. | 登録日 | 2018-06-01 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
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6GO7
| TdT chimera (Loop1 of pol mu) - full DNA synapsis complex | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*C)-3'), ... | 著者 | Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. | 登録日 | 2018-06-01 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
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6GO5
| TdT chimera (Loop1 of pol mu) - Ternary complex with 1-nt gapped DNA substrate | 分子名称: | 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(*AP*CP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*GP*GP*CP*AP*AP*AP*CP*A)-3'), ... | 著者 | Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. | 登録日 | 2018-06-01 | 公開日 | 2019-06-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
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6GO6
| TdT chimera (Loop1 of pol mu) - ternary complex with downstream dsDNA | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*GP*GP*C)-3'), ... | 著者 | Loc'h, J, Gerodimos, C.A, Rosario, S, Lieber, M.R, Delarue, M. | 登録日 | 2018-06-01 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction. J.Biol.Chem., 294, 2019
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