4C4X
 
 | | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9 | | 分子名称: | 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | | 登録日 | 2013-09-09 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
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1XA8
 | | Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa) | | 分子名称: | GLUTATHIONE, GLYCEROL, Glutathione-dependent formaldehyde-activating enzyme, ... | | 著者 | Neculai, A.M, Neculai, D, Griesinger, C, Vorholt, J.A, Becker, S. | | 登録日 | 2004-08-25 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A dynamic zinc redox switch
J.Biol.Chem., 280, 2005
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1X6M
 | | Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa) | | 分子名称: | GLYCEROL, Glutathione-dependent formaldehyde-activating enzyme, SULFATE ION, ... | | 著者 | Neculai, A.M, Neculai, D, Vorholt, J.A, Becker, S. | | 登録日 | 2004-08-11 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A dynamic zinc redox switch
J.Biol.Chem., 280, 2005
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2YAT
 | | Crystal structure of estradiol derived metal chelate and estrogen receptor-ligand binding domain complex | | 分子名称: | ESTRADIOL-PYRIDINIUM TETRAACETIC ACID, ESTROGEN RECEPTOR, EUROPIUM ION, ... | | 著者 | Li, M.J, Greenblatt, H.M, Dym, O, Albeck, S, Degani, H, Sussman, J.L. | | 登録日 | 2011-02-24 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | | 主引用文献 | Structure of Estradiol Metal Chelate and Estrogen Receptor Complex: The Basis for Designing a New Class of Selective Estrogen Receptor Modulators.
J.Med.Chem., 54, 2011
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6FHE
 | | Highly active enzymes by automated modular backbone assembly and sequence design | | 分子名称: | Synthetic construct | | 著者 | Lapidot, G, Khersonsky, O, Lipsh, R, Dym, O, Albeck, S, Rogotner, S, Fleishman, J.S. | | 登録日 | 2018-01-14 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Highly active enzymes by automated combinatorial backbone assembly and sequence design.
Nat Commun, 9, 2018
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2J80
 | | Structure of Citrate-bound Periplasmic Domain of Sensor Histidine Kinase CitA | | 分子名称: | CITRATE ANION, GLYCEROL, SENSOR KINASE CITA, ... | | 著者 | Sevvana, M, Vijayan, V, Zweckstetter, M, Reinelt, S, Madden, D.R, Sheldrick, G.M, Bott, M, Griesinger, C, Becker, S. | | 登録日 | 2006-10-18 | | 公開日 | 2007-10-23 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase Cita.
J.Mol.Biol., 377, 2008
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6FFW
 | | Phosphotriesterase PTE_A53_5 | | 分子名称: | (4~{S},6~{R})-2,2,6-trimethyl-1,3-dioxan-4-ol, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-01-09 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.495 Å) | | 主引用文献 | Phosphotriesterase
PTE_A53_5
To Be Published
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6FQE
 | | Phosphotriesterase PTE_A53_4 | | 分子名称: | (4~{S},6~{R})-2,2,6-trimethyl-1,3-dioxan-4-ol, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-02-14 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Phosphotriesterase
PTE_A53_4
To Be Published
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6FHF
 | | Highly active enzymes by automated modular backbone assembly and sequence design | | 分子名称: | Design, SODIUM ION | | 著者 | Lapidot, G, Khersonsky, O, Lipsh, R, Dym, O, Albeck, S, Rogotner, S, Fleishman, J.S. | | 登録日 | 2018-01-14 | | 公開日 | 2018-07-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Highly active enzymes by automated combinatorial backbone assembly and sequence design.
Nat Commun, 9, 2018
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6G1J
 | | Phosphotriesterase PTE_C23M_1 | | 分子名称: | 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-03-21 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Phosphotriesterase
PTE_C23M_1
To Be Published
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6FWE
 | | Phosphotriesterase PTE_C23_6 | | 分子名称: | 1-[methoxy(methyl)phosphoryl]oxyethane, 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-03-06 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.774 Å) | | 主引用文献 | Phosphotriesterase
PTE_C23_6
To Be Published
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6FRZ
 | | Phosphotriesterase PTE_A53_7 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-methylcyclohexane-1,1,3,3-tetrol, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-02-18 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Phosphotriesterase
PTE_A53_7
To Be Published
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6GC2
 | | AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface | | 分子名称: | Heavy chain, Light Chain | | 著者 | Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J. | | 登録日 | 2018-04-17 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
Plos Comput.Biol., 15, 2019
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6FU6
 | | Phosphotriesterase PTE_C23_2 | | 分子名称: | FORMIC ACID, POLYACRYLIC ACID, Parathion hydrolase, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-02-26 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Phosphotriesterase
PTE_A53_4
To Be Published
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6G3M
 | | Phosphotriesterase PTE_C23M_4 | | 分子名称: | 1-ethyl-1-methyl-cyclohexane, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | | 登録日 | 2018-03-26 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | | 主引用文献 | Phosphotriesterase
PTE_C23M_4
To Be Published
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3BTP
 | | Crystal structure of Agrobacterium tumefaciens VirE2 in complex with its chaperone VirE1: a novel fold and implications for DNA binding | | 分子名称: | AMMONIUM ION, DI(HYDROXYETHYL)ETHER, Protein virE1, ... | | 著者 | Dym, O, Albeck, S, Unger, T, Elbaum, M, Israel Structural Proteomics Center (ISPC) | | 登録日 | 2007-12-30 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2GZU
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5HQ3
 | | Stable, high-expression variant of human acetylcholinesterase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetylcholinesterase, O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP | | 著者 | Goldenzweig, A, Goldsmith, M, Hill, S.E, Gertman, O, Laurino, P, Ashani, Y, Dym, O, Albeck, S, Unger, T, Prilusky, J, Lieberman, R.L, Aharoni, A, Silman, I, Sussman, J.L, Tawfik, D.S, Fleishman, S.J. | | 登録日 | 2016-01-21 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Mol.Cell, 63, 2016
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2KOX
 | | NMR residual dipolar couplings identify long range correlated motions in the backbone of the protein ubiquitin | | 分子名称: | Ubiquitin | | 著者 | Fenwick, R.B, Richter, B, Lee, D, Walter, K.F.A, Milovanovic, D, Becker, S, Lakomek, N.A, Griesinger, C, Salvatella, X. | | 登録日 | 2009-10-02 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Weak Long-Range Correlated Motions in a Surface Patch of Ubiquitin Involved in Molecular Recognition
J.Am.Chem.Soc., 2011
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8B1P
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8B1O
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3UFE
 | | Structure of transcriptional antiterminator (BGLG-family) at 1.5 A resolution | | 分子名称: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Grosse, C, Himmel, S, Becker, S, Sheldrick, G.M, Uson, I. | | 登録日 | 2011-11-01 | | 公開日 | 2012-02-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of transcriptional antiterminator (BGLG-family) at 1.5 A resolution
To be Published
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2LYP
 | | NOE-based 3D structure of the monomer of CylR2 in equilibrium with predissociated homodimer at 266K (-7 Celsius degrees) | | 分子名称: | CylR2 | | 著者 | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | | 登録日 | 2012-09-19 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
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2LYJ
 | | NOE-based 3D structure of the CylR2 homodimer at 298K | | 分子名称: | CylR2 | | 著者 | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Giller, K, Becker, S, Zweckstetter, M, Schwieters, C.D. | | 登録日 | 2012-09-19 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
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2LYK
 | | NOE-based 3D structure of the CylR2 homodimer at 270K (-3 Celsius degrees) | | 分子名称: | CylR2 | | 著者 | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | | 登録日 | 2012-09-19 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
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