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3Q4I
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BU of 3q4i by Molmil
Crystal structure of CDP-Chase in complex with Gd3+
分子名称: GADOLINIUM ION, Phosphohydrolase (MutT/nudix family protein)
著者Duong-Ly, K.C, Gabelli, S.B, Amzel, L.M.
登録日2010-12-23
公開日2011-07-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities.
J.Bacteriol., 193, 2011
3PHM
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BU of 3phm by Molmil
REDUCED (CU+) PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE (PHM)
分子名称: AZIDE ION, COPPER (II) ION, GLYCEROL, ...
著者Prigge, S.T, Amzel, L.M.
登録日1999-05-25
公開日1999-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substrate-mediated electron transfer in peptidylglycine alpha-hydroxylating monooxygenase.
Nat.Struct.Biol., 6, 1999
5C8L
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BU of 5c8l by Molmil
Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, NudF protein, ...
著者Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M.
登録日2015-06-25
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
Plos One, 10, 2015
3TUR
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BU of 3tur by Molmil
Crystal Structure of M. tuberculosis LD-transpeptidase type 2 complexed with a peptidoglycan fragment
分子名称: 6-CARBOXYLYSINE, D-GLUTAMIC ACID, Di-mu-iodobis(ethylenediamine)diplatinum(II), ...
著者Bianchet, M.A, Erdemli, S.B, Gupta, R, Lamichhane, G, Amzel, L.M.
登録日2011-09-17
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Targeting the Cell Wall of Mycobacterium tuberculosis: Structure and Mechanism of L,D-Transpeptidase 2.
Structure, 20, 2012
3U1Q
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Crystal Structure of M. tuberculosis LD-transpeptidase type 2 with 2-Mercaptoethanol
分子名称: BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, Mycobacteria Tuberculosis LD-transpeptidase type 2
著者Erdemli, S, Bianchet, M.A, Gupta, R, Lamichhane, G, Amzel, L.M.
登録日2011-09-30
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of Mycobacterium tuberculosis L,D-transpeptidase 2 provides insights into targeting the cell wall of persisters
to be published
1PFC
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BU of 1pfc by Molmil
MOLECULAR-REPLACEMENT STRUCTURE OF GUINEA PIG IGG1 P*FC(PRIME) REFINED AT 3.1 ANGSTROMS RESOLUTION
分子名称: IGG1 PFC' FC
著者Bryant, S.H, Amzel, L.M, Poljak, R.J, Phizackerley, R.P.
登録日1981-10-28
公開日1982-02-03
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3.125 Å)
主引用文献Molecular-Replacement Structure of Guinea Pig Igg1 Pfc(Prime) Refined at 3.1 Angstroms Resolution
Acta Crystallogr.,Sect.B, 41, 1985
1YIP
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BU of 1yip by Molmil
Oxidized Peptidylglycine Alpha-Hydroxylating Monooxygenase (PHM) in a New Crystal Form
分子名称: COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase
著者Siebert, X, Eipper, B.A, Mains, R.E, Prigge, S.T, Blackburn, N.J, Amzel, L.M.
登録日2005-01-12
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Catalytic Copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also Plays a Critical Structural Role.
Biophys.J., 89, 2005
1YJK
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Reduced Peptidylglycine Alpha-Hydroxylating Monooxygenase (PHM) in a New Crystal Form
分子名称: COPPER (II) ION, GLYCEROL, Peptidyl-glycine alpha-amidating monooxygenase
著者Siebert, X, Eipper, B.A, Mains, R.E, Prigge, S.T, Blackburn, N.J, Amzel, L.M.
登録日2005-01-14
公開日2005-11-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Catalytic Copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also Plays a Critical Structural Role.
Biophys.J., 89, 2005
1YJL
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Reduced Peptidylglycine alpha-Hydroxylating Monooxygenase in a new crystal form
分子名称: Peptidyl-glycine alpha-amidating monooxygenase
著者Siebert, X, Eipper, B.A, Mains, R.E, Prigge, S.T, Blackburn, N.J, Amzel, L.M.
登録日2005-01-14
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The catalytic copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also plays a critical structural role.
Biophys.J., 89, 2005
1YHM
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BU of 1yhm by Molmil
Structure of the complex of Trypanosoma cruzi farnesyl disphosphate synthase with alendronate, Isopentenyl diphosphate and mg+2
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, MAGNESIUM ION, ...
著者Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
登録日2005-01-09
公開日2005-12-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005
1YHL
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BU of 1yhl by Molmil
Structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with risedronate, dmapp and mg+2
分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, ...
著者Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
登録日2005-01-09
公開日2005-12-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005
1YI9
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BU of 1yi9 by Molmil
Crystal Structure Analysis of the oxidized form of the M314I mutant of Peptidylglycine alpha-Hydroxylating Monooxygenase
分子名称: COPPER (II) ION, GLYCEROL, Peptidyl-glycine alpha-amidating monooxygenase
著者Siebert, X, Eipper, B.A, Mains, R.E, Prigge, S.T, Blackburn, N.J, Amzel, L.M.
登録日2005-01-11
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The catalytic copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also plays a critical structural role.
Biophys.J., 89, 2005
1YHK
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Trypanosoma cruzi farnesyl diphosphate synthase
分子名称: SULFATE ION, farnesyl pyrophosphate synthase
著者Gabelli, S.B, McLellan, J.S, Montalvetti, A, Oldfield, E, Docampo, R, Amzel, L.M.
登録日2005-01-09
公開日2005-12-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
Proteins, 62, 2005
1KHZ
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BU of 1khz by Molmil
Structure of the ADPR-ase in complex with AMPCPR and Mg
分子名称: ADP-ribose pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, CHLORIDE ION, ...
著者Gabelli, S.B, Bianchet, M.A, Bessman, M.J, Amzel, L.M.
登録日2001-12-01
公開日2002-10-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Mechanism of the Escherichia coli ADP-ribose pyrophosphatase, a Nudix hydrolase.
Biochemistry, 41, 2002
1K12
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BU of 1k12 by Molmil
Fucose Binding lectin
分子名称: CALCIUM ION, CHLORIDE ION, LECTIN, ...
著者Bianchet, M.A, Odom, E.W, Vasta, G.R, Amzel, L.M.
登録日2001-09-23
公開日2002-07-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel fucose recognition fold involved in innate immunity.
Nat.Struct.Biol., 9, 2002
4DZW
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BU of 4dzw by Molmil
Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.B.
登録日2012-03-01
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
4DXJ
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Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.B.
登録日2012-02-27
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
4DWG
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BU of 4dwg by Molmil
Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, Farnesyl pyrophosphate synthase, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.B.
登録日2012-02-24
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
4E1E
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BU of 4e1e by Molmil
Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-hexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.B.
登録日2012-03-06
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
4E4Z
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Oxidized (Cu2+) peptidylglycine alpha-hydroxylating monooxygenase (PHM) in complex with hydrogen peroxide (1.98 A)
分子名称: COPPER (II) ION, GLYCEROL, HYDROGEN PEROXIDE, ...
著者Rudzka, K, Amzel, L.M.
登録日2012-03-13
公開日2013-01-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Coordination of peroxide to the Cu(M) center of peptidylglycine alpha-hydroxylating monooxygenase (PHM): structural and computational study.
J.Biol.Inorg.Chem., 18, 2013
4DWB
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BU of 4dwb by Molmil
Crystal structure of Trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, Farnesyl pyrophosphate synthase, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.B.
登録日2012-02-24
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
6ALV
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BU of 6alv by Molmil
Crystal structure of H107A-peptidylglycine alpha-hydroxylating monooxygenase (PHM) mutant (no CuH bound)
分子名称: AZIDE ION, COPPER (II) ION, GLYCEROL, ...
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-08
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6AN3
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BU of 6an3 by Molmil
Crystal structure of H172A-peptidylglycine alpha-hydroxylating monooxygenase (PHM) mutant soaked with peptide (no CuH bound, no peptide bound)
分子名称: COPPER (II) ION, DI(HYDROXYETHYL)ETHER, Peptidyl-glycine alpha-amidating monooxygenase
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-11
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6AY0
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BU of 6ay0 by Molmil
Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) soaked with peptide
分子名称: COPPER (II) ION, Peptidyl-glycine alpha-amidating monooxygenase
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-09-07
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018
6AO6
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BU of 6ao6 by Molmil
Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM)
分子名称: COPPER (II) ION, GLYCEROL, NICKEL (II) ION, ...
著者Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M.
登録日2017-08-15
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase.
Commun Biol, 1, 2018

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