1YIP

Oxidized Peptidylglycine Alpha-Hydroxylating Monooxygenase (PHM) in a New Crystal Form

Summary for 1YIP

Entry DOI	10.2210/pdb1yip/pdb
Related	1OPM 1PHM 1SDW 1YI9 3PHM
Descriptor	Peptidyl-glycine alpha-amidating monooxygenase, COPPER (II) ION (3 entities in total)
Functional Keywords	monooxygenase, bioactive peptide activation, copper, ascorbate, oxidoreductase
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein: P14925
Total number of polymer chains	1
Total formula weight	34801.85
Authors	Siebert, X.,Eipper, B.A.,Mains, R.E.,Prigge, S.T.,Blackburn, N.J.,Amzel, L.M. (deposition date: 2005-01-12, release date: 2005-11-15, Last modification date: 2023-08-23)
Primary citation	Siebert, X.,Eipper, B.A.,Mains, R.E.,Prigge, S.T.,Blackburn, N.J.,Amzel, L.M. The Catalytic Copper of Peptidylglycine alpha-Hydroxylating Monooxygenase also Plays a Critical Structural Role. Biophys.J., 89:3312-3319, 2005 Cited by PubMed: 16100265 DOI: 10.1529/biophysj.105.066100 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation