5AJJ
 
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2J47
 | | Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor | | 分子名称: | (5R,6R,7R,8S)-8-(ACETYLAMINO)-6,7-DIHYDROXY-5-(HYDROXYMETHYL)-N-PHENYL-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDE, GLUCOSAMINIDASE, GLYCEROL | | 著者 | Dennis, R.J, Davies, G.J. | | 登録日 | 2006-08-25 | | 公開日 | 2006-10-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Inhibition of O-Glcnacase by a Gluco-Configured Nagstatin and a Pugnac-Imidazole Hybrid Inhibitor
Chem. Commun., 42, 2006
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3LCA
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1JBK
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3KQI
 | | crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | | 分子名称: | CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ... | | 著者 | Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M. | | 登録日 | 2009-11-17 | | 公開日 | 2010-02-02 | | 最終更新日 | 2019-02-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285, 2010
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4QQF
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3QFP
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3QML
 | | The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor | | 分子名称: | 78 kDa glucose-regulated protein homolog, MAGNESIUM ION, Nucleotide exchange factor SIL1, ... | | 著者 | Yan, M, Li, J.Z, Sha, B.D. | | 登録日 | 2011-02-04 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
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3QFU
 | | Crystal structure of Yeast Hsp70 (Bip/kar2) complexed with ADP | | 分子名称: | 78 kDa glucose-regulated protein homolog, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yan, M, Li, J.Z, Sha, B.D. | | 登録日 | 2011-01-22 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
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3QLE
 | | Structural Basis for the Function of Tim50 in the Mitochondrial Presequence Translocase | | 分子名称: | ACETATE ION, CALCIUM ION, PENTAETHYLENE GLYCOL, ... | | 著者 | Qian, X.G, Gebert, M, Hpker, J, Yan, M, Li, J.Z, Wiedemann, N, Laan, M.V.D, Pfanner, N, Sha, B.D. | | 登録日 | 2011-02-02 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.831 Å) | | 主引用文献 | Structural basis for the function of tim50 in the mitochondrial presequence translocase.
J.Mol.Biol., 411, 2011
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3QD2
 | | Crystal structure of mouse PERK kinase domain | | 分子名称: | Eukaryotic translation initiation factor 2-alpha kinase 3 | | 著者 | Wenjun, C, Jingzhi, L, David, R, Bingdong, S. | | 登録日 | 2011-01-17 | | 公開日 | 2011-04-27 | | 最終更新日 | 2019-01-16 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | The structure of the PERK kinase domain suggests the mechanism for its activation.
Acta Crystallogr.,Sect.D, 67, 2011
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1COH
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6YVW
 | | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with monocyclic BB-328 | | 分子名称: | 4-[(5-bromanyl-4,6-dimethyl-pyridin-2-yl)amino]-4-oxidanylidene-butanoic acid, Egl nine homolog 1, FE (III) ION, ... | | 著者 | Chowdhury, R, Banerji, B, Schofield, C.J. | | 登録日 | 2020-04-28 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2.
Sci Rep, 10, 2020
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6YW1
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6YW2
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6YW3
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6YVZ
 | | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic JLS-367 | | 分子名称: | 4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | | 著者 | Chowdhury, R, Sorensen, J.L, Schofield, C.J. | | 登録日 | 2020-04-29 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2.
Sci Rep, 10, 2020
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6P7M
 | | Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex) | | 分子名称: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | | 著者 | Knott, G.J, Liu, J.J, Doudna, J.A. | | 登録日 | 2019-06-06 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
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5F8V
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4MCN
 | | Human SOD1 C57S Mutant, Metal-free | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn] | | 著者 | Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S. | | 登録日 | 2013-08-21 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.
J.Biol.Chem., 290, 2015
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6UUM
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6UUL
 | | Crystal structure of broad and potent HIV-1 neutralizing antibody 438-D5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, D5 Fab Heavy Chain, ... | | 著者 | Kumar, S, Wilson, I.A. | | 登録日 | 2019-10-30 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite.
Sci Adv, 6, 2020
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6UTK
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6UUH
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6V6W
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