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4RIK
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BU of 4rik by Molmil
Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77
分子名称: Alpha-synuclein
著者Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
5K2F
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BU of 5k2f by Molmil
Structure of NNQQNY from yeast prion Sup35 with cadmium acetate determined by MicroED
分子名称: ACETATE ION, CADMIUM ION, Eukaryotic peptide chain release factor GTP-binding subunit
著者Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2016-05-18
公開日2016-09-14
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1 Å)
主引用文献Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
5K2E
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BU of 5k2e by Molmil
Structure of NNQQNY from yeast prion Sup35 with zinc acetate determined by MicroED
分子名称: ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION
著者Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2016-05-18
公開日2016-09-14
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1 Å)
主引用文献Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
5K2G
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BU of 5k2g by Molmil
Structure of GNNQQNY from yeast prion Sup35 in space group P21 determined by MicroED
分子名称: Eukaryotic peptide chain release factor GTP-binding subunit
著者Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2016-05-18
公開日2016-09-14
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.1 Å)
主引用文献Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
5K2H
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BU of 5k2h by Molmil
Structure of GNNQQNY from yeast prion Sup35 in space group P212121 determined by MicroED
分子名称: Eukaryotic peptide chain release factor GTP-binding subunit
著者Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2016-05-18
公開日2016-09-14
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.05 Å)
主引用文献Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
6PQ5
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BU of 6pq5 by Molmil
AGAAAA segment 113-118 from human prion
分子名称: MALONATE ION, Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
5ME8
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BU of 5me8 by Molmil
N-terminal domain of the human tumor suppressor ING5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5
著者Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R.
登録日2016-11-14
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
5MTO
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BU of 5mto by Molmil
N-terminal domain of the human tumor suppressor ING5 C19S mutant
分子名称: Inhibitor of growth protein 5, SODIUM ION, SULFATE ION
著者Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J.
登録日2017-01-10
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
8T0B
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BU of 8t0b by Molmil
Novel Domain of Unknown Function Solved with AlphaFold
分子名称: DUF1842 domain-containing protein
著者Miller, J.E, Cascio, D, Sawaya, M.R, Yeates, T.O.
登録日2023-05-31
公開日2024-01-17
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.
Acta Crystallogr D Struct Biol, 80, 2024
8T1M
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BU of 8t1m by Molmil
Novel Domain of Unknown Function Solved with AlphaFold
分子名称: DUF1842 domain-containing protein
著者Miller, J.E, Agdanowski, M.P, Cascio, D, Sawaya, M.R, Yeates, T.O.
登録日2023-06-02
公開日2024-01-17
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography.
Acta Crystallogr D Struct Biol, 80, 2024
6PQA
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BU of 6pqa by Molmil
GAVVGG segment 119-124 from human prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2019-07-08
公開日2020-04-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
5WIA
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BU of 5wia by Molmil
Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-18
公開日2018-04-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.002 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WKD
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BU of 5wkd by Molmil
Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-07-25
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WHN
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BU of 5whn by Molmil
Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317
分子名称: Segment of TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-17
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WKB
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BU of 5wkb by Molmil
MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-07-24
公開日2018-05-23
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WHP
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BU of 5whp by Molmil
Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317
分子名称: Segment of TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-17
公開日2018-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WIQ
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BU of 5wiq by Molmil
Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-19
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
7QYD
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BU of 7qyd by Molmil
mosquitocidal Cry11Ba determined at pH 6.5 from naturally-occurring nanocrystals by Serial femtosecond crystallography
分子名称: Pesticidal crystal protein Cry11Ba
著者De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P, Sawaya, M.R, Schibrowsky, N.A, Cascio, D, Rodriguez, J.A.
登録日2022-01-28
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7R1E
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BU of 7r1e by Molmil
Mosquitocidal Cry11Ba determined at pH 10.4 from naturally-occurring nanocrystals by Serial femtosecond crystallography
分子名称: GLYCEROL, Pesticidal crystal protein Cry11Ba
著者Colletier, J.-P, Sawaya, M.R, Schibrowsky, N.A, Cascio, D, Rodriguez, J.A.
登録日2022-02-02
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
8DZZ
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BU of 8dzz by Molmil
Cryo-EM structure of chi dynein bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
8E00
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BU of 8e00 by Molmil
Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation.
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
6V8R
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BU of 6v8r by Molmil
Proteinase K Determined by MicroED Phased by ARCIMBOLDO_SHREDDER
分子名称: CALCIUM ION, Proteinase K
著者Richards, L.S, Martynowycz, M.W, Sawaya, M.R, Millan, C.
登録日2019-12-11
公開日2020-08-12
実験手法ELECTRON CRYSTALLOGRAPHY (1.6 Å)
主引用文献Fragment-based determination of a proteinase K structure from MicroED data using ARCIMBOLDO_SHREDDER
Acta Crystallogr.,Sect.D, 76, 2020
7N2G
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BU of 7n2g by Molmil
MicroED structure of human CPEB3 segment(154-161) kinked polymorph phased by ARCIMBOLDO-BORGES
分子名称: CPEB3
著者Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R.
登録日2021-05-29
公開日2022-06-01
最終更新日2024-05-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.201 Å)
主引用文献Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
7N2J
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BU of 7n2j by Molmil
MicroED structure of a mutant mammalian prion segment phased by ARCIMBOLDO-BORGES
分子名称: prion protein
著者Richards, L.S, Flores, M.D, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R.
登録日2021-05-29
公開日2022-06-01
最終更新日2024-05-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.5 Å)
主引用文献Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023
7N2F
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BU of 7n2f by Molmil
MicroED structure of human CPEB3 segment (154-161) straight polymorph phased by ARCIMBOLDO-BORGES
分子名称: CPEB3
著者Flores, M.D, Richards, L.S, Zee, C.T, Glynn, C, Gallagher-Jones, M, Sawaya, M.R.
登録日2021-05-29
公開日2022-06-01
最終更新日2024-05-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.2 Å)
主引用文献Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED.
Acs Bio Med Chem Au, 3, 2023

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