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2DSB
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BU of 2dsb by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5
分子名称: ADP-sugar pyrophosphatase
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2DSC
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BU of 2dsc by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and ADP-ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
2DSD
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BU of 2dsd by Molmil
Crystal structure of human ADP-ribose pyrophosphatase NUDT5 in complex with magnesium and AMP
分子名称: ADENOSINE MONOPHOSPHATE, ADP-sugar pyrophosphatase, MAGNESIUM ION
著者Zha, M, Zhong, C, Ding, J.
登録日2006-06-28
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of Human NUDT5 Reveal Insights into the Structural Basis of the Substrate Specificity
J.Mol.Biol., 364, 2006
7ETT
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BU of 7ett by Molmil
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit
著者Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J.
登録日2021-05-14
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
7ETV
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BU of 7etv by Molmil
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit DFPFV
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit
著者Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J.
登録日2021-05-14
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
7ETU
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BU of 7etu by Molmil
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit SFPFT
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit
著者Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J.
登録日2021-05-14
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
4J4V
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BU of 4j4v by Molmil
Pentameric SFTSVN with suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4X
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BU of 4j4x by Molmil
Crystal structure of GraVN
分子名称: NP protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4W
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BU of 4j4w by Molmil
Crystal structure of BueVN
分子名称: Nucleocapsid
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.661 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4Y
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BU of 4j4y by Molmil
Triple mutant GraVN
分子名称: NP protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-06-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4U
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BU of 4j4u by Molmil
Pentamer SFTSVN
分子名称: Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4R
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BU of 4j4r by Molmil
Hexameric SFTSVN
分子名称: Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4S
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BU of 4j4s by Molmil
Triple mutant SFTAVN
分子名称: Nucleocapsid protein, SODIUM ION
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.442 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
分子名称: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
著者Knapp, M.S, Elling, R.A.
登録日2014-06-06
公開日2014-11-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
8JYS
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BU of 8jys by Molmil
SARS-CoV-2 Spike RBD (dimer) in complex with two 2S-1244 nanobodies
分子名称: IBT-CoV144 nanobody, Spike protein S1
著者Yang, Y, Zhang, C.H.
登録日2023-07-03
公開日2024-06-12
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献A novel nanobody broadly neutralizes SARS-CoV-2 via induction of spike trimer dimers conformation.
Exploration (Beijing), 4, 2024
5GRF
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BU of 5grf by Molmil
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5GRL
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BU of 5grl by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ISOCITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
4FZ7
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BU of 4fz7 by Molmil
Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide
分子名称: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK
著者Kuglstatter, A, Slade, M.
登録日2012-07-06
公開日2013-07-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
J. Med. Chem., 57, 2014
6KJV
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BU of 6kjv by Molmil
Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
著者Song, G.
登録日2019-07-23
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
5YO4
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BU of 5yo4 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond K27C-A79C
分子名称: Soluble cytochrome b562
著者Pu, M, Xu, Z, Song, G, Liu, Z.J.
登録日2017-10-26
公開日2018-03-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOC
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BU of 5yoc by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond C102-R125C
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
著者Pu, M, Xu, Z, Song, G, Liu, Z.J.
登録日2017-10-27
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOG
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BU of 5yog by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond N14C-C93
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL, ...
著者Pu, M, Xu, Z, Song, G, Liu, Z.J.
登録日2017-10-27
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO5
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BU of 5yo5 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond A20C-Q25C
分子名称: Soluble cytochrome b562
著者Pu, M, Xu, Z, Song, G, Liu, Z.J.
登録日2017-10-26
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOE
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BU of 5yoe by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond A43C-L74C
分子名称: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
著者Pu, M, Xu, Z, Song, G, Liu, Z.J.
登録日2017-10-27
公開日2017-12-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YM7
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BU of 5ym7 by Molmil
Crystal Structure of B562RIL without disulfide bond
分子名称: Soluble cytochrome b562
著者Pu, M, Xu, Z, Song, G, Liu, Z.J.
登録日2017-10-21
公開日2017-11-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.56225181 Å)
主引用文献Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018

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