5Y59
 
 | | Crystal structure of Ku80 and Sir4 | | 分子名称: | ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p | | 著者 | Chen, H, Xue, J, Wu, J, Lei, M. | | 登録日 | 2017-08-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
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5Y5A
 | | Crystal structure of Est1 and Cdc13 | | 分子名称: | KLLA0F20702p, KLLA0F20922p | | 著者 | Chen, H, Xue, J, Wu, J, Lei, M. | | 登録日 | 2017-08-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
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6MLC
 | | PHD6 domain of MLL3 in complex with histone H4 | | 分子名称: | GLYCEROL, Histone H4, Histone-lysine N-methyltransferase 2C, ... | | 著者 | Dong, A, Liu, Y, Qin, S, Lei, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-09-27 | | 公開日 | 2018-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.
Nat Commun, 10, 2019
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5WQD
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5Y58
 | | Crystal structure of Ku70/80 and TLC1 | | 分子名称: | ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit 2, TLC1 | | 著者 | Chen, H, Xue, J, Wu, J, Lei, M. | | 登録日 | 2017-08-08 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
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5XUP
 | | Crystal structure of TRF1 and TERB1 | | 分子名称: | Telomere repeats-binding bouquet formation protein 1, Telomeric repeat-binding factor 1 | | 著者 | Long, J, Huang, C, Wu, J, Lei, M. | | 登録日 | 2017-06-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Telomeric TERB1-TRF1 interaction is crucial for male meiosis.
Nat. Struct. Mol. Biol., 24, 2017
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8HMD
 | | base module state 2 of Tetrahymena IFT-A | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | | 著者 | Ma, Y, Wu, J, Lei, M. | | 登録日 | 2022-12-03 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
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8HME
 | | head module state 1 of Tetrahymena IFT-A | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | | 著者 | Ma, Y, Wu, J, Lei, M. | | 登録日 | 2022-12-03 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
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8HMC
 | | base module state 1 of Tetrahymena IFT-A | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | | 著者 | Ma, Y, Wu, J, Lei, M. | | 登録日 | 2022-12-03 | | 公開日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
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3RSN
 | | Crystal Structure of the N-terminal region of Human Ash2L | | 分子名称: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | | 著者 | Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M. | | 登録日 | 2011-05-02 | | 公開日 | 2011-06-22 | | 最終更新日 | 2011-12-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
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8HPP
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8HMF
 | | head module state 2 of Tetrahymena IFT-A | | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | | 著者 | Ma, Y, Wu, J, Lei, M. | | 登録日 | 2022-12-03 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
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3RMH
 | | Crystal Structure of yeast telomere protein Cdc13 OB4 | | 分子名称: | Yeast Cdc13 OB4 | | 著者 | Sun, J, Yang, Y, Lei, M. | | 登録日 | 2011-04-20 | | 公開日 | 2011-11-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70.
Mol.Cell.Biol., 32, 2012
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3U85
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3U86
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3U4V
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3U4Z
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3U88
 | | Crystal structure of human menin in complex with MLL1 and LEDGF | | 分子名称: | (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ... | | 著者 | Huang, J, Wan, B, Lei, M. | | 登録日 | 2011-10-16 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
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3TOJ
 | | Structure of the SPRY domain of human Ash2L | | 分子名称: | Set1/Ash2 histone methyltransferase complex subunit ASH2 | | 著者 | Chen, Y, Cao, F, Wan, B, Dou, Y, Lei, M. | | 登録日 | 2011-09-05 | | 公開日 | 2012-01-25 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.
Cell Res., 22, 2012
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3U50
 | | Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C | | 分子名称: | Telomerase-associated protein 82, ZINC ION | | 著者 | Zeng, Z, Huang, J, Yang, Y, Lei, M. | | 登録日 | 2011-10-10 | | 公開日 | 2011-12-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3U84
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3U58
 | | Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 AB | | 分子名称: | DNA (5'-D(*GP*GP*GP*T)-3'), Tetrahymena Teb1 AB | | 著者 | Zeng, Z, Huang, J, Yang, Y, Lei, M. | | 登録日 | 2011-10-11 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.613 Å) | | 主引用文献 | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7WTD
 | | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | | 登録日 | 2022-02-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
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7WTE
 | | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | | 登録日 | 2022-02-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
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7WTA
 | | Cryo-EM structure of human pyruvate carboxylase in apo state | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | | 登録日 | 2022-02-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA.
Mol.Cell, 82, 2022
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