4K6M
 
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7EX8
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 27 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | 著者 | Kuang, W, Hu, Z, Gong, P. | | 登録日 | 2021-05-26 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX2
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with L-742,001 (methyl ester form) | | 分子名称: | MANGANESE (II) ION, Replicase, methyl (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(phenylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoate | | 著者 | Kuang, W, Hu, Z, Gong, P. | | 登録日 | 2021-05-26 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7DTE
 | | SARS-CoV-2 RdRP catalytic complex with T33-1 RNA | | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA (33-MER), ... | | 著者 | Wang, Q, Gong, P. | | 登録日 | 2021-01-04 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex.
Cell Rep, 37, 2021
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7D6N
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7D6M
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7EX7
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 16 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | 著者 | Kuang, W, Hu, Z, Gong, P. | | 登録日 | 2021-05-26 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX4
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 5 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | 著者 | Kuang, W, Hu, Z, Gong, P. | | 登録日 | 2021-05-26 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX3
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 3 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | 著者 | Kuang, W, Hu, Z, Gong, P. | | 登録日 | 2021-05-26 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX9
 | | Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 28 | | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Replicase, ... | | 著者 | Kuang, W, Hu, Z, Gong, P. | | 登録日 | 2021-05-26 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
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7EX6
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7EWZ
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7EWW
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7EWV
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7EWX
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7EX1
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7EX0
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7EWY
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7EWU
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7EKJ
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7FJT
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8Z97
 | | Cryo-EM structure of Thogoto virus polymerase in transcription elongation conformation | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Xue, L, Chang, T, Chen, X, Xiong, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8Z8N
 | | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 3 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | | 著者 | Xue, L, Chang, T, Chen, X, Xiong, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8Z9R
 | | Cryo-EM structure of Thogoto virus polymerase in a replication elongation-reception conformation | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ... | | 著者 | Xue, L, Chang, T, Chen, X, Xiong, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8Z9Q
 | | Cryo-EM structure of Thogoto virus polymerase in a replication reception conformation | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ... | | 著者 | Xue, L, Chang, T, Chen, X, Xiong, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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