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1LO6
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BU of 1lo6 by Molmil
Human Kallikrein 6 (hK6) active form with benzamidine inhibitor at 1.56 A resolution
分子名称: BENZAMIDINE, Kallikrein 6, MAGNESIUM ION
著者Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Dhanarajan, P, Thompson, S.M, Blaber, M.
登録日2002-05-06
公開日2002-05-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal structure and biochemical characterization of human kallikrein 6 reveals a trypsin-like kallikrein is expressed in the central nervous system
To be Published
2NTD
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BU of 2ntd by Molmil
Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations
分子名称: Acidic fibroblast growth factor 1, FORMIC ACID
著者Dubey, V.K, Blaber, M.
登録日2006-11-07
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
4YOL
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BU of 4yol by Molmil
Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
著者Xia, X, Blaber, M.
登録日2015-03-11
公開日2016-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.
J.Pharm.Sci., 105, 2016
1L2E
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BU of 1l2e by Molmil
Human Kallikrein 6 (hK6) Active Form with benzamidine inhibitor
分子名称: BENZAMIDINE, Kallikrein 6, MAGNESIUM ION
著者Bernett, M.J, Blaber, S.I, Scarisbrick, I.A, Blaber, M.
登録日2002-02-20
公開日2002-05-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system.
J.Biol.Chem., 277, 2002
2HWA
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BU of 2hwa by Molmil
Crystal structure of Lys12Thr/Cys117Val mutant of human acidic fibroblast growth factor at 1.65 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HW9
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BU of 2hw9 by Molmil
Crystal structure of Lys12Cys/Cys117Val mutant of human acidic fibroblast Growth factor at 1.60 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
2HWM
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BU of 2hwm by Molmil
Crystal structure of Lys12Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.60 angstrom resolution
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-01
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions.
J.Mol.Biol., 371, 2007
9ILB
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BU of 9ilb by Molmil
HUMAN INTERLEUKIN-1 BETA
分子名称: PROTEIN (HUMAN INTERLEUKIN-1 BETA)
著者Yu, B, Blaber, M, Gronenborn, A.M, Clore, G.M, Caspar, D.L.D.
登録日1998-10-22
公開日1999-01-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 96, 1999
1JT5
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BU of 1jt5 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)
分子名称: SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JTC
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BU of 1jtc by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F)
分子名称: FORMIC ACID, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT3
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BU of 1jt3 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V)
分子名称: SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JQZ
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BU of 1jqz by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag.
分子名称: FORMIC ACID, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-09
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1K5U
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BU of 1k5u by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with His93 replaced by Gly (H93G).
分子名称: Acidic fibroblast growth factor, SULFATE ION
著者Kim, J, Blaber, S.I, Blaber, M.
登録日2001-10-12
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
1K5V
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BU of 1k5v by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with Asn106 replaced by Gly (N106G).
分子名称: Acidic fibroblast growth factor, SULFATE ION
著者Kim, J, Blaber, S.I, Blaber, M.
登録日2001-10-12
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
1JT4
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BU of 1jt4 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L)
分子名称: FORMIC ACID, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1JT7
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BU of 1jt7 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)
分子名称: FORMIC ACID, SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
1YTO
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BU of 1yto by Molmil
Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-02-10
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
1SPJ
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BU of 1spj by Molmil
STRUCTURE OF MATURE HUMAN TISSUE KALLIKREIN (HUMAN KALLIKREIN 1 OR KLK1) AT 1.70 ANGSTROM RESOLUTION WITH VACANT ACTIVE SITE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ...
著者Laxmikanthan, G, Blaber, S.I, Bernett, M.J, Blaber, M.
登録日2004-03-16
公開日2005-01-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.70 A X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding
Proteins, 58, 2005
3O4C
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BU of 3o4c by Molmil
Crystal structure of Symfoil-4V: de novo designed beta-trefoil architecture with symmetric primary structure
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ...
著者Lee, J, Blaber, M.
登録日2010-07-26
公開日2010-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O3Q
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BU of 3o3q by Molmil
Crystal structure of "L44F/M67I/L73V/A103G/deletion 104-106/F108Y/V109L/L111I/C117V/R119G/deletion 120-122" mutant form of Human acidic fibroblast growth factor
分子名称: GLYCEROL, Heparin-binding growth factor 1
著者Lee, J, Blaber, M.
登録日2010-07-25
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A polypeptide "building block"top-down symmetric deconstruction".
J.Mol.Biol., 407, 2011
3CRG
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BU of 3crg by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala
分子名称: FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ...
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CQA
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BU of 3cqa by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-02
公開日2009-04-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CRI
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BU of 3cri by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3CRH
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BU of 3crh by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
1M9H
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BU of 1m9h by Molmil
Corynebacterium 2,5-DKGR A and Phe 22 replaced with Tyr (F22Y), Lys 232 replaced with Gly (K232G), Arg 238 replaced with His (R238H)and Ala 272 replaced with Gly (A272G)in presence of NADH cofactor
分子名称: 2,5-diketo-D-gluconic acid reductase A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Sanli, G, Blaber, M.
登録日2002-07-29
公開日2003-08-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase
Protein Sci., 13, 2004

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