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2P3T
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BU of 2p3t by Molmil
Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide
分子名称: 3-CHLORO-4-(2-METHYLAMINO-IMIDAZOL-1-YLMETHYL)-THIOPHENE-2-CARBOXYLIC ACID [4-CHLORO-2-(5-CHLORO-PYRIDIN-2-YLCARBAMOYL)-6-METHOXY-PHENYL]-AMIDE, CALCIUM ION, CHLORIDE ION, ...
著者Adler, M, Whitlow, M.
登録日2007-03-09
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Thiophene-anthranilamides as highly potent and orally available factor xa inhibitors.
J.Med.Chem., 50, 2007
6FZJ
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BU of 6fzj by Molmil
PPAR gamma mutant complex
分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CHLORIDE ION, IODIDE ION, ...
著者Rochel, N.
登録日2018-03-14
公開日2019-02-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.011 Å)
主引用文献Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.
Nat Commun, 10, 2019
8SAH
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BU of 8sah by Molmil
Huntingtin C-HEAT domain in complex with HAP40
分子名称: 40-kDa huntingtin-associated protein, Huntingtin
著者Harding, R.J, Deme, J.C, Alteen, M.G, Arrowsmith, C.H, Lea, S.M, Structural Genomics Consortium (SGC)
登録日2023-03-31
公開日2023-04-26
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Structure, 31, 2023
8SBE
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BU of 8sbe by Molmil
Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM
分子名称: Vesicular glutamate transporter 2
著者Li, F, Finer-Moore, J, Eriksen, J, Cheng, Y, Edwards, R, Stroud, R.
登録日2023-04-03
公開日2023-05-03
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ion transport and regulation in a synaptic vesicle glutamate transporter.
Science, 368, 2020
6FZY
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BU of 6fzy by Molmil
PPAR mutant
分子名称: Peroxisome proliferator-activated receptor gamma
著者Rochel, N.
登録日2018-03-15
公開日2019-02-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.
Nat Commun, 10, 2019
8JHF
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BU of 8jhf by Molmil
Native SUV420H1 bound to 167-bp nucleosome
分子名称: DNA (160-MER), Histone H2A.Z, Histone H2B type 1-K, ...
著者Lin, F, Li, W.
登録日2023-05-23
公開日2023-11-15
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase.
Cell Discov, 9, 2023
8JHG
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BU of 8jhg by Molmil
Native SUV420H1 bound to 167-bp nucleosome
分子名称: DNA (160-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Lin, F, Li, W.
登録日2023-05-23
公開日2023-11-22
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase.
Cell Discov, 9, 2023
6FZG
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BU of 6fzg by Molmil
PPAR gamma mutant complex
分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, CHLORIDE ION, Peroxisome proliferator-activated receptor gamma
著者Rochel, N.
登録日2018-03-14
公開日2019-02-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.
Nat Commun, 10, 2019
6FZF
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BU of 6fzf by Molmil
PPAR mutant complex
分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
著者Rochel, N.
登録日2018-03-14
公開日2019-02-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.
Nat Commun, 10, 2019
6FZP
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BU of 6fzp by Molmil
PPAR gamma complex.
分子名称: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
著者Rochel, N, Beji, S.
登録日2018-03-15
公開日2019-02-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.
Nat Commun, 10, 2019
3HAD
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BU of 3had by Molmil
BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE)
著者Barycki, J.J, Bratt, J.M, Banaszak, L.J.
登録日1998-12-03
公開日2000-01-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism.
Biochemistry, 38, 1999
6NTY
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BU of 6nty by Molmil
2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain
分子名称: PHOSPHATE ION, RNA-binding protein Musashi homolog 2
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Lan, L, Xiaoqing, W, Cooper, A, Gao, F.P, Xu, L.
登録日2019-01-30
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 88, 2020
6TUR
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BU of 6tur by Molmil
human XPG, Apo1 form
分子名称: DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells
著者Ruiz, F.M, Fernandez-Tornero, C.
登録日2020-01-08
公開日2020-09-16
最終更新日2020-10-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
6TUX
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BU of 6tux by Molmil
human XPG-DNA, Complex 2
分子名称: DNA (5'-D(P*AP*AP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*AP*GP*TP*T)-3'), DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells
著者Ruiz, F.M, Fernandez-Tornero, C.
登録日2020-01-08
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
6TUW
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BU of 6tuw by Molmil
human XPG-DNA, Complex 1
分子名称: DNA (5'-D(P*GP*AP*AP*CP*TP*CP*TP*G)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*AP*GP*TP*TP*C)-3'), DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells
著者Ruiz, F.M, Fernandez-Tornero, C.
登録日2020-01-08
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
6TUS
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BU of 6tus by Molmil
human XPG, Apo2 form
分子名称: DNA repair protein complementing XP-G cells,DNA repair protein complementing XP-G cells, GLYCEROL, SULFATE ION
著者Ruiz, F.M, Fernandez-Tornero, C.
登録日2020-01-08
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Nucleic Acids Res., 48, 2020
5INW
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BU of 5inw by Molmil
Structure of reaction loop cleaved lamprey angiotensinogen
分子名称: C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION
著者Wei, H, Zhou, A.
登録日2016-03-08
公開日2016-10-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism
J.Biol.Chem., 291, 2016
6NLE
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BU of 6nle by Molmil
X-ray structure of LeuT with V269 deletion
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Navratna, V, Yang, D, Gouaux, E.
登録日2019-01-08
公開日2020-01-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.615 Å)
主引用文献Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion inSLC6A3.
Proc.Natl.Acad.Sci.USA, 116, 2019
7TLT
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BU of 7tlt by Molmil
SARS-CoV-2 Spike-derived peptide S489-497 (YFPLQSYGF) presented by HLA-A*29:02
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
著者Murdolo, L.D, Szeto, C, Gras, S.
登録日2022-01-18
公開日2022-10-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ablation of CD8 + T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3.
Nat Commun, 13, 2022
6OWJ
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BU of 6owj by Molmil
Zn-mediated polymerization of human SFPQ
分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION
著者Lee, M.
登録日2019-05-10
公開日2020-02-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ.
Nucleic Acids Res., 48, 2020
3LRA
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BU of 3lra by Molmil
Structural Basis for Assembling a Human Tripartite Complex Dlg1-MPP7-Mals3
分子名称: Disks large homolog 1, MAGUK p55 subfamily member 7, Protein lin-7 homolog C
著者Yang, X, Xie, X, Shen, Y, Long, J.
登録日2010-02-10
公開日2010-11-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis for tandem L27 domain-mediated polymerization
Faseb J., 24, 2010
7FJO
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BU of 7fjo by Molmil
Cryo-EM structure of South African (B.1.351) SARS-CoV-2 spike glycoprotein in complex with three T6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, T6 heavy chain, ...
著者Wang, X, Zhang, L, Zhang, S, Liang, Q.
登録日2021-08-04
公開日2022-04-13
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022
7FJN
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BU of 7fjn by Molmil
Cryo-EM structure of South African (B.1.351) SARS-CoV-2 spike glycoprotein in complex with two T6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein, T6 heavy chain, ...
著者Wang, X, Zhang, L, Zhang, S, Liang, Q.
登録日2021-08-04
公開日2022-04-27
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022
1LSJ
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BU of 1lsj by Molmil
Crystal Structure of the E110Q Mutant of L-3-Hydroxyacyl-CoA Dehydrogenase in Complex with NAD
分子名称: 3-HYDROXYACYL-COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Barycki, J.J, Banaszak, L.J.
登録日2002-05-17
公開日2004-02-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the E110Q Mutant of L-3-Hydroxyacyl-CoA Dehydrogenase in Complex with NAD
To be Published
7FJS
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BU of 7fjs by Molmil
Crystal structure of T6 Fab bound to theSARS-CoV-2 RBD of B.1.351
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, T6 heavy chain, ...
著者Wang, X, Zhang, L, Zhang, S, Liang, Q.
登録日2021-08-04
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022

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