7Q0A
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![BU of 7q0a by Molmil](/molmil-images/mine/7q0a) | SARS-CoV-2 Spike ectodomain with Fab FI3A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI3A fab Light chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2021-10-14 | 公開日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
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5IJ3
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![BU of 5ij3 by Molmil](/molmil-images/mine/5ij3) | SrpA adhesin in complex with sialyl T antigen | 分子名称: | ACETATE ION, CALCIUM ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, ... | 著者 | Iverson, T.M. | 登録日 | 2016-03-01 | 公開日 | 2017-02-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of the Streptococcus sanguinis SrpA Binding Region with Human Sialoglycans Suggest Features of the Physiological Ligand. Biochemistry, 2016
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5IQ9
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![BU of 5iq9 by Molmil](/molmil-images/mine/5iq9) | Crystal structure of 10E8v4 Fab in complex with an HIV-1 gp41 peptide. | 分子名称: | 10E8v4 Heavy Chain, 10E8v4 Light Chain, gp41 MPER peptide | 著者 | Ofek, G, Kwon, Y.D, Caruso, W, Kwong, P.D. | 登録日 | 2016-03-10 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. J.Virol., 90, 2016
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6EFC
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![BU of 6efc by Molmil](/molmil-images/mine/6efc) | Hsa Siglec + Unique domains (unliganded) | 分子名称: | CALCIUM ION, SODIUM ION, Streptococcal hemagglutinin | 著者 | Iverson, T.M. | 登録日 | 2018-08-16 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6EFI
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![BU of 6efi by Molmil](/molmil-images/mine/6efi) | SK678 binding region (Siglec + Unique) | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, COBALT (II) ION, ... | 著者 | Iverson, T.M. | 登録日 | 2018-08-16 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.715 Å) | 主引用文献 | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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8QJR
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![BU of 8qjr by Molmil](/molmil-images/mine/8qjr) | BRG1 bromodomain in complex with VBC via compound 17 | 分子名称: | (2S,4R)-1-[(2R)-2-[3-[2-[4-[3-[4-[(1R,5S)-3-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]pyridin-2-yl]oxycyclobutyl]oxypiperidin-1-yl]ethoxy]-1,2-oxazol-5-yl]-3-methyl-butanoyl]-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, CHLORIDE ION, Elongin-B, ... | 著者 | Kerry, P.S, Hole, A.J, Perez-Dorado, J.I. | 登録日 | 2023-09-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem., 67, 2024
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6ER3
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![BU of 6er3 by Molmil](/molmil-images/mine/6er3) | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,3 sialyllactose | 分子名称: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | 著者 | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | 登録日 | 2017-10-16 | 公開日 | 2018-05-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
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6EFB
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![BU of 6efb by Molmil](/molmil-images/mine/6efb) | GspB Siglec domain | 分子名称: | CALCIUM ION, GLYCEROL, SK150 siglec + Unique, ... | 著者 | Iverson, T.M. | 登録日 | 2018-08-16 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6EF7
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![BU of 6ef7 by Molmil](/molmil-images/mine/6ef7) | GspB Siglec domain | 分子名称: | CALCIUM ION, Platelet binding protein GspB | 著者 | Iverson, T.M. | 登録日 | 2018-08-16 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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6EFA
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![BU of 6efa by Molmil](/molmil-images/mine/6efa) | GspB Siglec + Unique domains | 分子名称: | CALCIUM ION, Platelet binding protein GspB | 著者 | Iverson, T.M. | 登録日 | 2018-08-16 | 公開日 | 2020-02-19 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
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8QJS
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![BU of 8qjs by Molmil](/molmil-images/mine/8qjs) | VHL/Elongin B/Elongin C complex with compound 155 | 分子名称: | (2S,4R)-1-[(2R)-2-[3-[2-(2-methoxyethoxy)ethoxy]-1,2-oxazol-5-yl]-3-methyl-butanoyl]-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | 著者 | Kerry, P.S, Hole, A.J, Perez-Dorado, J.I. | 登録日 | 2023-09-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.191 Å) | 主引用文献 | PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem., 67, 2024
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8QJT
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![BU of 8qjt by Molmil](/molmil-images/mine/8qjt) | BRM (SMARCA2) Bromodomain in complex with ligand 10 | 分子名称: | 2-[6-azanyl-5-[(1R,5S)-8-[2-(2-methoxyethoxy)pyridin-4-yl]-3,8-diazabicyclo[3.2.1]octan-3-yl]pyridazin-3-yl]phenol, CHLORIDE ION, Probable global transcription activator SNF2L2, ... | 著者 | Kerry, P.S, Hole, A.J, Perez-Dorado, J.I. | 登録日 | 2023-09-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.568 Å) | 主引用文献 | PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. J.Med.Chem., 67, 2024
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6LBI
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![BU of 6lbi by Molmil](/molmil-images/mine/6lbi) | |
6L6Q
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![BU of 6l6q by Molmil](/molmil-images/mine/6l6q) | |
5WHV
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![BU of 5whv by Molmil](/molmil-images/mine/5whv) | Crystal structure of ArtB | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ArtB protein, CALCIUM ION, ... | 著者 | Gao, X, Galan, J.E. | 登録日 | 2017-07-18 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | Evolution of host adaptation in the Salmonella typhoid toxin. Nat Microbiol, 2, 2017
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6LBM
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6L5M
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![BU of 6l5m by Molmil](/molmil-images/mine/6l5m) | Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2 | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5L
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![BU of 6l5l by Molmil](/molmil-images/mine/6l5l) | Crystal structure of human DEAD-box RNA helicase DDX21 at apo state | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2 | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5N
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![BU of 6l5n by Molmil](/molmil-images/mine/6l5n) | Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2020-08-12 | 実験手法 | X-RAY DIFFRACTION (2.242 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5O
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![BU of 6l5o by Molmil](/molmil-images/mine/6l5o) | Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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7DCN
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![BU of 7dcn by Molmil](/molmil-images/mine/7dcn) | |
7DCM
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![BU of 7dcm by Molmil](/molmil-images/mine/7dcm) | Crystal structure of CITX | 分子名称: | Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, ZINC ION | 著者 | Xu, H, Wang, B, Su, X.D. | 登録日 | 2020-10-26 | 公開日 | 2021-11-03 | 最終更新日 | 2023-05-17 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Co-evolution-based prediction of metal-binding sites in proteomes by machine learning. Nat.Chem.Biol., 19, 2023
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8ABV
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![BU of 8abv by Molmil](/molmil-images/mine/8abv) | Crystal structure of SpLdpA in complex with erythro-DGPD | 分子名称: | (1R,2S)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, (1S,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, GLYCEROL, ... | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.683 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABT
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![BU of 8abt by Molmil](/molmil-images/mine/8abt) | Crystal structure of NaLdpA in complex with the product analog Resveratrol | 分子名称: | RESVERATROL, SULFATE ION, SnoaL-like domain-containing protein | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABU
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![BU of 8abu by Molmil](/molmil-images/mine/8abu) | Crystal structure of NaLdpA mutant H97Q in complex with erythro-DGPD | 分子名称: | (1S,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, SnoaL-like domain-containing protein | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | 登録日 | 2022-07-04 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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