2Z2U
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4J7U
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![BU of 4j7u by Molmil](/molmil-images/mine/4j7u) | Crystal structure of human sepiapterin reductase in complex with sulfathiazole | 分子名称: | 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Groenlund Pedersen, M, Pojer, F, Johnsson, K. | 登録日 | 2013-02-14 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs. Science, 340, 2013
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1VST
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2YDL
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![BU of 2ydl by Molmil](/molmil-images/mine/2ydl) | Crystal structure of SH3C from CIN85 | 分子名称: | SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1 | 著者 | Bravo, J, Cardenes, N. | 登録日 | 2011-03-22 | 公開日 | 2012-03-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications. Plos One, 8, 2013
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1CB2
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![BU of 1cb2 by Molmil](/molmil-images/mine/1cb2) | CELLOBIOHYDROLASE II, CATALYTIC DOMAIN, MUTANT Y169F | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE II, alpha-D-mannopyranose | 著者 | Kleywegt, G.J, Szardenings, M, Jones, T.A. | 登録日 | 1995-11-25 | 公開日 | 1996-10-14 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The active site of Trichoderma reesei cellobiohydrolase II: the role of tyrosine 169. Protein Eng., 9, 1996
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4H1U
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![BU of 4h1u by Molmil](/molmil-images/mine/4h1u) | Nucleotide-free human dynamin-1-like protein GTPase-GED fusion | 分子名称: | CITRATE ANION, Dynamin-1-like protein | 著者 | Wenger, J, Klinglmayr, E, Puehringer, S, Goettig, P. | 登録日 | 2012-09-11 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses. Plos One, 8, 2013
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1CLC
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4AQR
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![BU of 4aqr by Molmil](/molmil-images/mine/4aqr) | Crystal structure of calmodulin in complex with the regulatory domain of a plasma-membrane Ca2+-ATPase | 分子名称: | CALCIUM ION, CALCIUM-TRANSPORTING ATPASE 8, PLASMA MEMBRANE-TYPE, ... | 著者 | Tidow, H, Poulsen, L.R, Andreeva, A, Hein, K.L, Palmgren, M.G, Nissen, P. | 登録日 | 2012-04-19 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A Bimodular Mechanism of Calcium Control in Eukaryotes Nature, 491, 2012
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1T8O
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![BU of 1t8o by Molmil](/molmil-images/mine/1t8o) | CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | 分子名称: | Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION | 著者 | Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O. | 登録日 | 2004-05-13 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344, 2004
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1T8N
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![BU of 1t8n by Molmil](/molmil-images/mine/1t8n) | CRYSTAL STRUCTURE OF THE P1 THR BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | 分子名称: | Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION | 著者 | Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O. | 登録日 | 2004-05-13 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344, 2004
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1T8L
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![BU of 1t8l by Molmil](/molmil-images/mine/1t8l) | CRYSTAL STRUCTURE OF THE P1 MET BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | 分子名称: | Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION | 著者 | Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O. | 登録日 | 2004-05-13 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344, 2004
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1PA2
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![BU of 1pa2 by Molmil](/molmil-images/mine/1pa2) | ARABIDOPSIS THALIANA PEROXIDASE A2 | 分子名称: | CALCIUM ION, MAGNESIUM ION, PEROXIDASE, ... | 著者 | Henriksen, A. | 登録日 | 1999-05-18 | 公開日 | 2000-11-15 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification. Plant Mol.Biol., 44, 2000
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1FO0
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![BU of 1fo0 by Molmil](/molmil-images/mine/1fo0) | MURINE ALLOREACTIVE SCFV TCR-PEPTIDE-MHC CLASS I MOLECULE COMPLEX | 分子名称: | NATURALLY PROCESSED OCTAPEPTIDE PBM1, PROTEIN (ALLOGENEIC H-2KB MHC CLASS I MOLECULE), PROTEIN (BETA-2 MICROGLOBULIN), ... | 著者 | Reiser, J.B, Darnault, C, Guimezanes, A, Gregoire, C, Mosser, T, Schmitt-Verhulst, A.-M, Fontecilla-Camps, J.C, Malissen, B, Housset, D, Mazza, G. | 登録日 | 2000-08-24 | 公開日 | 2000-10-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat.Immunol., 1, 2000
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7UN5
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7UMQ
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1Q2E
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![BU of 1q2e by Molmil](/molmil-images/mine/1q2e) | CELLOBIOHYDROLASE CEL7A WITH LOOP DELETION 245-252 AND BOUND NON-HYDROLYSABLE CELLOTETRAOSE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EXOCELLOBIOHYDROLASE I, ... | 著者 | Stahlberg, J, Harris, M, Jones, T.A. | 登録日 | 2003-07-24 | 公開日 | 2003-11-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A.
A comparison with Phanerochaete chrysosporium Cel7D J.Mol.Biol., 333, 2003
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1Q2B
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![BU of 1q2b by Molmil](/molmil-images/mine/1q2b) | CELLOBIOHYDROLASE CEL7A WITH DISULPHIDE BRIDGE ADDED ACROSS EXO-LOOP BY MUTATIONS D241C AND D249C | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, EXOCELLOBIOHYDROLASE I | 著者 | Stahlberg, J, Harris, M, Jones, T.A. | 登録日 | 2003-07-24 | 公開日 | 2003-11-25 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Engineering the exo-loop of Trichoderma reesei cellobiohydrolase, Cel7A.
A comparison with Phanerochaete chrysosporium Cel7D. J.Mol.Biol., 333, 2003
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1T8M
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![BU of 1t8m by Molmil](/molmil-images/mine/1t8m) | CRYSTAL STRUCTURE OF THE P1 HIS BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | 分子名称: | Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION | 著者 | Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O. | 登録日 | 2004-05-13 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344, 2004
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1T7C
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![BU of 1t7c by Molmil](/molmil-images/mine/1t7c) | CRYSTAL STRUCTURE OF THE P1 GLU BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | 分子名称: | Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION | 著者 | Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O. | 登録日 | 2004-05-09 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344, 2004
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2BSL
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![BU of 2bsl by Molmil](/molmil-images/mine/2bsl) | Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,4-dihydroxybenzoate | 分子名称: | 3,4-DIHYDROXYBENZOIC ACID, ACETATE ION, DIHYDROOROTATE DEHYDROGENASE A, ... | 著者 | Wolfe, A.E, Hansen, M, Gattis, S.G, Hu, Y.-C, Johansson, E, Arent, S, Larsen, S, Palfey, B.A. | 登録日 | 2005-05-23 | 公開日 | 2006-08-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Interaction of Benzoate Pyrimidine Analogues with Class 1A Dihydroorotate Dehydrogenase from Lactococcus Lactis. Biochemistry, 46, 2007
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2BX7
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![BU of 2bx7 by Molmil](/molmil-images/mine/2bx7) | Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,5-dihydroxybenzoate | 分子名称: | 3,5-DIHYDROXYBENZOATE, ACETATE ION, DIHYDROOROTATE DEHYDROGENASE, ... | 著者 | Wolfe, A.E, Hansen, M, Gattis, S.G, Hu, Y.-C, Johansson, E, Arent, S, Larsen, S, Palfey, B.A. | 登録日 | 2005-07-25 | 公開日 | 2006-08-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Interaction of Benzoate Pyrimidine Analogues with Class 1A Dihydroorotate Dehydrogenase from Lactococcus Lactis. Biochemistry, 46, 2007
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3CEL
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![BU of 3cel by Molmil](/molmil-images/mine/3cel) | ACTIVE-SITE MUTANT E212Q DETERMINED AT PH 6.0 WITH CELLOBIOSE BOUND IN THE ACTIVE SITE | 分子名称: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... | 著者 | Divne, C, Stahlberg, J, Jones, T.A. | 登録日 | 1996-08-24 | 公開日 | 1997-03-12 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Activity studies and crystal structures of catalytically deficient mutants of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 264, 1996
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2OXU
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![BU of 2oxu by Molmil](/molmil-images/mine/2oxu) | Uninhibited form of human MMP-12 | 分子名称: | CALCIUM ION, Macrophage metalloelastase, ZINC ION | 著者 | Calderone, V, Bertini, I, Fragai, M, Luchinat, C, Maletta, M, Yeo, K.J. | 登録日 | 2007-02-21 | 公開日 | 2007-03-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Snapshots of the reaction mechanism of matrix metalloproteinases. ANGEW.CHEM.INT.ED.ENGL., 45, 2006
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2WI6
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![BU of 2wi6 by Molmil](/molmil-images/mine/2wi6) | Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone | 分子名称: | 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE, HEAT SHOCK PROTEIN, HSP90-ALPHA | 著者 | Brough, P.A, Barril, X, Borgognoni, J, Chene, P, Davies, N.G.M, Davis, B, Drysdale, M.J, Dymock, B, Eccles, S.A, Garcia-Echeverria, C, Fromont, C, Hayes, A, Hubbard, R.E, Jordan, A.M, Rugaard-Jensen, M, Massey, A, Merret, A, Padfield, A, Parsons, R, Radimerski, T, Raynaud, F.I, Robertson, A, Roughley, S.D, Schoepfer, J, Simmonite, H, Surgenor, A, Valenti, M, Walls, S, Webb, P, Wood, M, Workman, P, Wright, L.M. | 登録日 | 2009-05-08 | 公開日 | 2009-07-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Combining Hit Identification Strategies: Fragment- Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-D]Pyrimidine Inhibitors of the Hsp90 Molecular Chaperone. J.Med.Chem., 52, 2009
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2WI1
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![BU of 2wi1 by Molmil](/molmil-images/mine/2wi1) | Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone | 分子名称: | 4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine, HEAT SHOCK PROTEIN HSP 90-ALPHA, MAGNESIUM ION | 著者 | Brough, P.A, Barril, X, Borgognoni, J, Chene, P, Davies, N.G.M, Davis, B, Drysdale, M.J, Dymock, B, Eccles, S.A, Garcia-Echeverria, C, Fromont, C, Hayes, A, Hubbard, R.E, Jordan, A.M, Rugaard-Jensen, M, Massey, A, Merret, A, Padfield, A, Parsons, R, Radimerski, T, Raynaud, F.I, Robertson, A, Roughley, S.D, Schoepfer, J, Simmonite, H, Surgenor, A, Valenti, M, Walls, S, Webb, P, Wood, M, Workman, P, Wright, L.M. | 登録日 | 2009-05-08 | 公開日 | 2009-07-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Combining Hit Identification Strategies: Fragment- Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-D]Pyrimidine Inhibitors of the Hsp90 Molecular Chaperone. J.Med.Chem., 52, 2009
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