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1P30
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BU of 1p30 by Molmil
Refinement of Adenovirus Type 5 Hexon with CNS
分子名称: Hexon protein
著者Rux, J.J, Kuser, P.R, Burnett, R.M.
登録日2003-04-16
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methods
J.VIROL., 77, 2003
1P2Z
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BU of 1p2z by Molmil
Refinement of Adenovirus Type 2 Hexon with CNS
分子名称: CITRIC ACID, Hexon protein
著者Rux, J.J, Kuser, P.R, Burnett, R.M.
登録日2003-04-16
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methods
J.VIROL., 77, 2003
2VL2
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BU of 2vl2 by Molmil
Oxidized and reduced forms of human peroxiredoxin 5
分子名称: BENZOIC ACID, PEROXIREDOXIN-5
著者Smeets, A, Declercq, J.P.
登録日2008-01-08
公開日2008-08-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.925 Å)
主引用文献The Crystal Structures of Oxidized Forms of Human Peroxiredoxin 5 with an Intramolecular Disulfide Bond Confirm the Proposed Enzymatic Mechanism for Atypical 2-Cys Peroxiredoxins.
Arch.Biochem.Biophys., 477, 2008
5O32
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BU of 5o32 by Molmil
The structure of complement complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xue, X, Wu, J, Forneris, F, Gros, P.
登録日2017-05-23
公開日2017-06-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.206209 Å)
主引用文献Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
2WIN
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BU of 2win by Molmil
C3 convertase (C3bBb) stabilized by SCIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ...
著者Wu, J, Janssen, B.J, Gros, P.
登録日2009-05-13
公開日2009-06-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
4PV0
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BU of 4pv0 by Molmil
Crystal structure of spleen tyrosine kinase (Syk) in complex with an imidazopyrazine inhibitor
分子名称: 4-[(3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzoyl)amino]benzoic acid, CHLORIDE ION, Tyrosine-protein kinase SYK
著者Lansdon, E.B, Mitchell, S.A.
登録日2014-03-14
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase.
J.Med.Chem., 57, 2014
5O35
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BU of 5o35 by Molmil
Structure of complement proteins complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Complement factor H,Complement factor H
著者Xue, X, Wu, J, Forneris, F, Gros, P.
登録日2017-05-23
公開日2017-06-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.
Nat. Struct. Mol. Biol., 24, 2017
2WII
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BU of 2wii by Molmil
Complement C3b in complex with factor H domains 1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ...
著者Wu, J, Janssen, B.J.C, Gros, P.
登録日2009-05-12
公開日2009-06-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of complement fragment C3b-factor H and implications for host protection by complement regulators.
Nat. Immunol., 10, 2009
4PUZ
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BU of 4puz by Molmil
Crystal structure of spleen tyrosine kinase (Syk) in complex with GS-9973
分子名称: 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine, Tyrosine-protein kinase SYK
著者Lansdon, E.B, Mitchell, S.A.
登録日2014-03-14
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.085 Å)
主引用文献Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase.
J.Med.Chem., 57, 2014
2XZR
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BU of 2xzr by Molmil
Escherichia coli Immunoglobulin-binding protein EibD 391-438 FUSED TO GCN4 ADAPTORS
分子名称: CHLORIDE ION, IMMUNOGLOBULIN-BINDING PROTEIN EIBD
著者Hartmann, M.D, Hernandez Alvarez, B, Ridderbusch, O, Deiss, S, Lupas, A.N.
登録日2010-11-28
公開日2011-07-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of E. Coli Igg-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins.
Structure, 19, 2011
4A4O
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BU of 4a4o by Molmil
CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 2-(2-AMINO- PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-PYRROLOPYRIDIN-4-ONE INHIBITOR
分子名称: 1-METHYL-2-(2-{[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO}PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ...
著者Bertrand, J.A, Bossi, R.T.
登録日2011-10-18
公開日2012-01-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4A4L
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BU of 4a4l by Molmil
CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR
分子名称: 1-METHYL-5-(2-{[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO}PYRIMIDIN-4-YL)-1H-PYRROLE-3-CARBOXAMIDE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ...
著者Bertrand, J.A, Bossi, R.T.
登録日2011-10-17
公開日2012-01-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4JNH
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BU of 4jnh by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
分子名称: Gag polyprotein
著者Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
登録日2013-03-15
公開日2013-05-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
2GOM
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BU of 2gom by Molmil
Crystal structure of Efb-C from Staphylococcus aureus
分子名称: Fibrinogen-binding protein
著者Hammel, M, Geisbrecht, B.V.
登録日2006-04-13
公開日2007-03-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A structural basis for complement inhibition by Staphylococcus aureus.
Nat.Immunol., 8, 2007
2GOX
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BU of 2gox by Molmil
Crystal structure of Efb-C / C3d Complex
分子名称: Complement C3, Fibrinogen-binding protein
著者Hammel, M, Geisbrecht, B.V.
登録日2006-04-14
公開日2007-03-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A structural basis for complement inhibition by Staphylococcus aureus.
Nat.Immunol., 8, 2007
2XSS
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BU of 2xss by Molmil
Crystal structure of GAFb from the human phosphodiesterase 5
分子名称: CGMP-SPECIFIC 3', 5'-CYCLIC PHOSPHODIESTERASE
著者Schlicker, C, Russwurm, M, Steegborn, C.
登録日2010-09-30
公開日2011-05-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Gaf-B Domain from Human Phosphodiesterase 5.
Proteins, 79, 2011
2XYI
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BU of 2xyi by Molmil
Crystal Structure of Nurf55 in complex with a H4 peptide
分子名称: DI(HYDROXYETHYL)ETHER, HISTONE H4, PROBABLE HISTONE-BINDING PROTEIN CAF1, ...
著者Stirnimann, C.U, Nowak, A.J, Mueller, C.W.
登録日2010-11-17
公開日2011-05-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Chromatin-Modifying Complex Component Nurf55/P55 Associates with Histones H3, H4 and Polycomb Repressive Complex 2 Subunit Su(Z)12 Through Partially Overlapping Binding Sites.
J.Biol.Chem., 286, 2011
3ZMF
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BU of 3zmf by Molmil
Salmonella enterica SadA 303-358 fused to GCN4 adaptors (SadAK2)
分子名称: GENERAL CONTROL PROTEIN GCN4, PUTATIVE INNER MEMBRANE PROTEIN
著者Hartmann, M.D, Hernandez Alvarez, B, Albrecht, R, Lupas, A.N.
登録日2013-02-08
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A New Expression System for Protein Crystallization Using Trimeric Coiled-Coil Adaptors.
Protein Eng.Des.Sel., 21, 2008
2HH3
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BU of 2hh3 by Molmil
Solution structure of the third KH domain of KSRP
分子名称: KH-type splicing regulatory protein
著者Garcia-Mayoral, M.F.
登録日2006-06-27
公開日2007-05-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
Structure, 15, 2007
3OHX
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BU of 3ohx by Molmil
Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.L.
登録日2010-08-18
公開日2010-09-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
2VL3
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BU of 2vl3 by Molmil
Oxidized and reduced forms of human peroxiredoxin 5
分子名称: PEROXIREDOXIN-5
著者Smeets, A, Declercq, J.P.
登録日2008-01-08
公開日2008-08-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The Crystal Structures of Oxidized Forms of Human Peroxiredoxin 5 with an Intramolecular Disulfide Bond Confirm the Proposed Enzymatic Mechanism for Atypical 2-Cys Peroxiredoxins.
Arch.Biochem.Biophys., 477, 2008
2HH2
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BU of 2hh2 by Molmil
Solution structure of the fourth KH domain of KSRP
分子名称: KH-type splicing regulatory protein
著者Garcia-Mayoral, M.F.
登録日2006-06-27
公開日2007-05-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
Structure, 15, 2007
1EDN
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BU of 1edn by Molmil
HUMAN ENDOTHELIN-1
分子名称: ENDOTHELIN-1
著者Wallace, B.A, Janes, R.W.
登録日1994-09-19
公開日1995-10-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献The crystal structure of human endothelin.
Nat.Struct.Biol., 1, 1994
4JMR
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BU of 4jmr by Molmil
A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid
分子名称: Env protein, Gag protein
著者Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J.
登録日2013-03-14
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
2WPQ
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BU of 2wpq by Molmil
Salmonella enterica SadA 479-519 fused to GCN4 adaptors (SadAK3, in- register fusion)
分子名称: CHLORIDE ION, NITRATE ION, TRIMERIC AUTOTRANSPORTER ADHESIN FRAGMENT
著者Hartmann, M.D, Hernandez Alvarez, B, Albrecht, R, Zeth, K, Lupas, A.N.
登録日2009-08-09
公開日2009-11-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Coiled-Coil Motif that Sequesters Ions to the Hydrophobic Core.
Proc.Natl.Acad.Sci.USA, 106, 2009

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