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3UG1
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BU of 3ug1 by Molmil
Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in the apo form
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor
著者Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S.
登録日2011-11-02
公開日2012-03-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 32, 2013
1IUC
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BU of 1iuc by Molmil
Fucose-specific lectin from Aleuria aurantia with three ligands
分子名称: Fucose-specific lectin, SULFATE ION, alpha-L-fucopyranose, ...
著者Fujihashi, M, Peapus, D.H, Kamiya, N, Nagata, Y, Miki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-01
公開日2003-09-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structure of Fucose-Specific Lectin from Aleuria aurantia Binding Ligands at Three of Its Five Sugar Recognition Sites
Biochemistry, 42, 2003
7EJQ
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BU of 7ejq by Molmil
Crystal structure of human transthyretin in complex with 8-chloro-9-oxo-9H-xanthene-3-carboxylic acid
分子名称: 8-chloranyl-9-oxidanylidene-xanthene-3-carboxylic acid, CALCIUM ION, Transthyretin
著者Kitakami, R, Yokoyama, T, Mizuguchi, M.
登録日2021-04-02
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.
Bioorg.Med.Chem., 44, 2021
7EJR
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BU of 7ejr by Molmil
Crystal structure of V30M mutated transthyretin in complex with 8-chloro-9-oxo-9H-xanthene-3-carboxylic acid
分子名称: 8-chloranyl-9-oxidanylidene-xanthene-3-carboxylic acid, CALCIUM ION, Transthyretin
著者Kitakami, R, Yokoyama, T, Mizuguchi, M.
登録日2021-04-02
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.
Bioorg.Med.Chem., 44, 2021
8GV1
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BU of 8gv1 by Molmil
Crystal structure of anti-FX IgG fab with FAST-Ig mutations
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Anti-factor X IgG fab heavy chain, ...
著者Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T.
登録日2022-09-14
公開日2023-06-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.186 Å)
主引用文献Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
8GV2
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BU of 8gv2 by Molmil
Crystal structure of anti-FX IgG fab without FAST-Ig mutations
分子名称: 1,2-ETHANEDIOL, Anti-factor X IgG fab heavy chain, Anti-factor X IgG fab light chain
著者Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T.
登録日2022-09-14
公開日2023-06-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.274 Å)
主引用文献Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
8GUZ
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BU of 8guz by Molmil
Crystal structure of anti-FIXa IgG fab with FAST-Ig mutations
分子名称: 1,2-ETHANEDIOL, Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain
著者Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T.
登録日2022-09-14
公開日2023-06-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
8GV0
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BU of 8gv0 by Molmil
Crystal structure of anti-FIXa IgG fab without FAST-Ig mutations
分子名称: Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain
著者Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T.
登録日2022-09-14
公開日2023-06-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.192 Å)
主引用文献Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
5C2I
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BU of 5c2i by Molmil
Crystal structure of Anabaena sp. DyP-type peroxidese (AnaPX)
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Alr1585 protein, ...
著者Yoshida, T, Amano, Y, Tsuge, H, Sugano, Y.
登録日2015-06-16
公開日2015-12-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Anabaena sp. DyP-type peroxidase is a tetramer consisting of two asymmetric dimers.
Proteins, 84, 2016
3WEB
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BU of 3web by Molmil
Crystal structure of a Niemann-Pick type C2 protein from Japanese carpenter ant in complex with oleic acid
分子名称: Niemann-Pick type C2 protein, OLEIC ACID
著者Fujimoto, Z, Tsuchiya, W, Ishida, Y, Yamazaki, T.
登録日2013-07-02
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Niemann-Pick type C2 protein mediating chemical communication in the worker ant
Proc.Natl.Acad.Sci.USA, 111, 2014
3KKQ
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BU of 3kkq by Molmil
Crystal structure of M-Ras P40D in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras
著者Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
登録日2009-11-06
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
5GXQ
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BU of 5gxq by Molmil
The crystal structure of the nucleosome containing H3.6
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Taguchi, H, Xie, Y, Horikoshi, N, Kurumizaka, H.
登録日2016-09-19
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
3WEA
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BU of 3wea by Molmil
Crystal structure of a Niemann-Pick type C2 protein from Japanese carpenter ant
分子名称: Niemann-Pick type C2 protein
著者Fujimoto, Z, Tsuchiya, W, Ishida, Y, Yamazaki, T.
登録日2013-07-02
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Niemann-Pick type C2 protein mediating chemical communication in the worker ant
Proc.Natl.Acad.Sci.USA, 111, 2014
5GSE
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BU of 5gse by Molmil
Crystal structure of unusual nucleosome
分子名称: DNA (250-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kato, D, Osakabe, A, Arimura, Y, Park, S.Y, Kurumizaka, H.
登録日2016-08-16
公開日2017-05-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Crystal structure of the overlapping dinucleosome composed of hexasome and octasome
Science, 356, 2017
7F5K
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BU of 7f5k by Molmil
Crystal structure of TCR4-1 ectodomain
分子名称: T cell receptor alpha chain, T cell receptor beta chain
著者Nagae, M, Yamasaki, S.
登録日2021-06-22
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.0000298 Å)
主引用文献Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b.
Nat Commun, 13, 2022
5YWX
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BU of 5ywx by Molmil
Crystal structure of hematopoietic prostaglandin D synthase in complex with F092
分子名称: GLUTATHIONE, GLYCEROL, Hematopoietic prostaglandin D synthase, ...
著者Kamo, M, Furubayashi, N, Inaka, K, Aritake, K, Omura, A, Tanaka, A.
登録日2017-11-30
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies.
Bioorg. Med. Chem., 26, 2018
4TV7
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BU of 4tv7 by Molmil
Crystal structure of Bacillus subtilis GabR at 2.05 Angstroms resolution
分子名称: HTH-type transcriptional regulatory protein GabR
著者Goto, M, Okuda, K, Yoshimura, T.
登録日2014-06-26
公開日2014-12-24
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator
Mol. Microbiol., 95, 2015
7X91
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BU of 7x91 by Molmil
The SARS-CoV-2 receptor binding domain bound with an Fv-clasp form of a human neutralizing antibody Ab496
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, An Fv-clasp version of the Ab496 heavy chain, An Fv-clasp version of the Ab496 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8Z
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BU of 7x8z by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab188
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab188 heavy chain, Ab188 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8Y
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BU of 7x8y by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab159
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab159 heavy chain, Ab159 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X8W
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BU of 7x8w by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab354
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab354 heavy chain, Ab354 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X90
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BU of 7x90 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab326
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab326 heavy chain, Ab326 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
7X92
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BU of 7x92 by Molmil
The SARS-CoV-2 receptor binding domain bound with the Fab fragment of a human neutralizing antibody Ab445
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab445 heavy chain, Ab445 light chain, ...
著者Kamada, K, Shirouzu, M.
登録日2022-03-15
公開日2022-12-07
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models.
Iscience, 25, 2022
3KKO
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BU of 3kko by Molmil
Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras, ...
著者Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
登録日2009-11-06
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
3KKM
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BU of 3kkm by Molmil
Crystal structure of H-Ras T35S in complex with GppNHp
分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T.
登録日2009-11-06
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010

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