6UKH
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7N5S
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![BU of 7n5s by Molmil](/molmil-images/mine/7n5s) | ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6) | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2021-06-06 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
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1EVC
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7N5T
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![BU of 7n5t by Molmil](/molmil-images/mine/7n5t) | ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5) | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2021-06-06 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
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1EUM
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![BU of 1eum by Molmil](/molmil-images/mine/1eum) | CRYSTAL STRUCTURE OF THE E.COLI FERRITIN ECFTNA | 分子名称: | FERRITIN 1 | 著者 | Stillman, T.J, Hempstead, P.D, Artymiuk, P.J, Andrews, S.C, Hudson, A.J, Treffry, A, Guest, J.R, Harrison, P.M. | 登録日 | 2000-04-17 | 公開日 | 2001-03-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The high-resolution X-ray crystallographic structure of the ferritin (EcFtnA) of Escherichia coli; comparison with human H ferritin (HuHF) and the structures of the Fe(3+) and Zn(2+) derivatives. J.Mol.Biol., 307, 2001
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1EXM
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![BU of 1exm by Molmil](/molmil-images/mine/1exm) | CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP. | 分子名称: | ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Hogg, T, Mesters, J.R, Hilgenfeld, R. | 登録日 | 2000-05-03 | 公開日 | 2000-06-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights into the GTPase Mechanism of EF-Tu from Structural Studies The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions, 28, 2000
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1EVB
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1EVA
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7MYN
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![BU of 7myn by Molmil](/molmil-images/mine/7myn) | Cryo-EM Structure of p110alpha in complex with p85alpha | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | 登録日 | 2021-05-21 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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1EVD
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7MYO
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![BU of 7myo by Molmil](/molmil-images/mine/7myo) | Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719 | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Yang, S, Hart, J.R, Xu, Y, Zou, X, Zhang, H, Zhou, Q, Xia, T, Zhang, Y, Yang, D, Wang, M.-W, Vogt, P.K. | 登録日 | 2021-05-21 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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7NFR
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![BU of 7nfr by Molmil](/molmil-images/mine/7nfr) | Fujian capmidlink domain in complex with Nb8194 | 分子名称: | GLYCEROL, NB8194, Polymerase basic protein 2, ... | 著者 | Keown, J.R, Grimes, J.M, Fodor, E. | 登録日 | 2021-02-07 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHX
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![BU of 7nhx by Molmil](/molmil-images/mine/7nhx) | 1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-11 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NIS
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![BU of 7nis by Molmil](/molmil-images/mine/7nis) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core | 分子名称: | Nanobody8192 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-13 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (5.96 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK6
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![BU of 7nk6 by Molmil](/molmil-images/mine/7nk6) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204 | 分子名称: | Nb8204, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (6.72 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK1
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![BU of 7nk1 by Molmil](/molmil-images/mine/7nk1) | 1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 | 分子名称: | Nanobody8201, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKI
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![BU of 7nki by Molmil](/molmil-images/mine/7nki) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core | 分子名称: | Nb8209, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-18 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.67 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NJ7
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![BU of 7nj7 by Molmil](/molmil-images/mine/7nj7) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core | 分子名称: | Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-16 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.82 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKA
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![BU of 7nka by Molmil](/molmil-images/mine/7nka) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 | 分子名称: | NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKR
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![BU of 7nkr by Molmil](/molmil-images/mine/7nkr) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210 | 分子名称: | Nb8210, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-18 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NFQ
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![BU of 7nfq by Molmil](/molmil-images/mine/7nfq) | Fujian capmidlink domain in complex with Nb8193 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Nb8193, ... | 著者 | Keown, J.R, Grimes, J.M, Fodor, E. | 登録日 | 2021-02-07 | 公開日 | 2021-12-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHA
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![BU of 7nha by Molmil](/molmil-images/mine/7nha) | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-10 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NIK
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![BU of 7nik by Molmil](/molmil-images/mine/7nik) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core | 分子名称: | Nanobody8189 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-12 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NI0
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![BU of 7ni0 by Molmil](/molmil-images/mine/7ni0) | 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-11 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NJ5
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![BU of 7nj5 by Molmil](/molmil-images/mine/7nj5) | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core | 分子名称: | Nb8199 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.63 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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