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Crystal structure of LOV2 (C450A) domain in complex with Zdk3
分子名称:	CHLORIDE ION, Engineered protein, Zdk3 affibody, ...
著者	Tarnawski, M, Wang, H, Yumerefendi, H, Hahn, K.M, Schlichting, I.
登録日	2015-09-02
公開日	2016-07-20
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	LOVTRAP: an optogenetic system for photoinduced protein dissociation. Nat.Methods, 13, 2016

Crystal structure of LOV2 (C450A) domain in complex with Zdk2
分子名称:	CHLORIDE ION, COPPER (II) ION, Engineered protein, ...
著者	Tarnawski, M, Wang, H, Yumerefendi, H, Hahn, K.M, Schlichting, I.
登録日	2015-09-02
公開日	2016-07-20
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (1.4 Å)
主引用文献	LOVTRAP: an optogenetic system for photoinduced protein dissociation. Nat.Methods, 13, 2016

Structure of human NAD(P) H:quinone oxidoreductase in complex with N-(2-bromophenyl)pyrrolidine-1-sulfonamide
分子名称:	FLAVIN-ADENINE DINUCLEOTIDE, N-(2-bromophenyl)pyrrolidine-1-sulfonamide, NAD(P)H dehydrogenase [quinone] 1
著者	Gruber, K, Hromic, A.
登録日	2018-03-10
公開日	2019-03-20
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.76 Å)
主引用文献	A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro. Febs Lett., 594, 2020

First-in-class small molecule inhibitors of Polycomb Repressive Complex 1 (PRC1) RING domain
分子名称:	3-(2-chlorophenyl)-4-ethyl-5-(1~{H}-indol-4-yl)-1~{H}-pyrrole-2-carboxylic acid, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, ...
著者	Cierpicki, T, Lund, G, Jaremko, L.
登録日	2021-01-29
公開日	2021-06-16
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nat.Chem.Biol., 17, 2021