3PEV
 
 | | S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 and IP6 | | 分子名称: | ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2010-10-27 | | 公開日 | 2011-03-23 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
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3PEY
 | | S. cerevisiae Dbp5 bound to RNA and ADP BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2010-10-27 | | 公開日 | 2011-03-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
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3RRN
 | | S. cerevisiae dbp5 l327v bound to gle1 h337r and ip6 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2011-04-29 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (4.001 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
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3RRM
 | | S. cerevisiae dbp5 l327v bound to nup159, gle1 h337r, ip6 and adp | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2011-04-29 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature, 472, 2011
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6EZD
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6BIT
 | | SIRPalpha antibody complex | | 分子名称: | KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | | 著者 | Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L. | | 登録日 | 2017-11-03 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.191 Å) | | 主引用文献 | Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6C2T
 | | Aurora A ligand complex | | 分子名称: | (2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid, Aurora kinase A, DIMETHYL SULFOXIDE, ... | | 著者 | Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S. | | 登録日 | 2018-01-08 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene.
Cancer Discov, 9, 2019
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7PNE
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7PNG
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6C2R
 | | Aurora A ligand complex | | 分子名称: | (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2-yl}methyl)-2-methylpiperidine-4-carboxylic acid, Aurora kinase A, SULFATE ION | | 著者 | Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S. | | 登録日 | 2018-01-08 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene.
Cancer Discov, 9, 2019
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1W2Q
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6F4Z
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6FFR
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1H4B
 | | SOLUTION STRUCTURE OF THE BIRCH POLLEN ALLERGEN BET V 4 | | 分子名称: | CALCIUM ION, POLCALCIN BET V 4 | | 著者 | Neudecker, P, Nerkamp, J, Eisenmann, A, Lauber, T, Lehmann, K, Schweimer, K, Roesch, P. | | 登録日 | 2003-02-26 | | 公開日 | 2004-02-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure, Dynamics, and Hydrodynamics of the Calcium-Bound Cross-Reactive Birch Pollen Allergen Bet V 4 Reveal a Canonical Monomeric Two EF-Hand Assembly with a Regulatory Function
J.Mol.Biol., 336, 2004
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1GS9
 | | Apolipoprotein E4, 22k domain | | 分子名称: | APOLIPOPROTEIN E | | 著者 | Verderame, J.R, Kantardjieff, K, Segelke, B, Weisgraber, K, Rupp, B. | | 登録日 | 2002-01-02 | | 公開日 | 2003-06-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of the 22K Domain of Human Apolipoprotein E4
To be Published
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6GQ9
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8V8Z
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8V9B
 | | Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732 | | 分子名称: | (2S,2'S)-3,3'-[carbonylbis(azanediyl-3,1-phenylene)]bis{2-[(3R)-pyrrolidin-1-ium-3-yl]propanoate}, Apolipoprotein(a), MAGNESIUM ION, ... | | 著者 | Hendle, J, Weichert, K, Sauder, J.M. | | 登録日 | 2023-12-07 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
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7O1H
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6ZL9
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8R6H
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8RW2
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8S1W
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8R6D
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8RZX
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