6N6T
 
 | | OXA-23 mutant F110A/M221A low pH form | | 分子名称: | Beta-lactamase oxa23, CITRATE ANION | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2018-11-27 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
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6N6X
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6N6U
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6N6Y
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4OH0
 | | Crystal structure of OXA-58 carbapenemase | | 分子名称: | Beta-lactamase OXA-58, CHLORIDE ION | | 著者 | Smith, C.A, Antunes, N.T, Toth, M, Vakulenko, S.B. | | 登録日 | 2014-01-16 | | 公開日 | 2014-02-26 | | 最終更新日 | 2014-04-02 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of Carbapenemase OXA-58 from Acinetobacter baumannii.
Antimicrob.Agents Chemother., 58, 2014
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6N6V
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4QC6
 | | Crystal structure of aminoglycoside 6'-acetyltransferase-Ie | | 分子名称: | (3R,5S,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3,5-diphosphaheptadecane-17-sulfinic acid 3,5-dioxide (non-preferred name), Bifunctional AAC/APH, FORMIC ACID, ... | | 著者 | Smith, C.A, Toth, M, Weiss, T.M, Frase, H, Vakulenko, S.B. | | 登録日 | 2014-05-09 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia revealed by crystallographic and small-angle X-ray scattering analysis.
Acta Crystallogr.,Sect.D, 70, 2014
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7LNR
 | | Structure of the avibactam-CDD-1 120 minute complex in imidazole and MPD | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B, Stewart, N.K. | | 登録日 | 2021-02-08 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7LNO
 | | Structure of apo-CDD-1 beta-lactamase in imidazole and MPD | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, SULFATE ION | | 著者 | Smith, C.A, Vakulenko, S.B, Stewart, N.K. | | 登録日 | 2021-02-08 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7LNQ
 | | Structure of the avibactam-CDD-1 3 minute complex in imidazole and MPD | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B, Stewart, N.K. | | 登録日 | 2021-02-08 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEF
 | | CDD-1 beta-lactamase in imidazole/MPD 10 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEE
 | | CDD-1 beta-lactamase in imidazole/MPD 6 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEC
 | | CDD-1 beta-lactamase in imidazole/MPD 4 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7ME9
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7MED
 | | CDD-1 beta-lactamase in imidazole/MPD 5 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEG
 | | CDD-1 beta-lactamase in imidazole/MPD 30 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEA
 | | CDD-1 beta-lactamase in imidazole/MPD 1 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEH
 | | CDD-1 beta-lactamase in imidazole/MPD 60 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7MEB
 | | CDD-1 beta-lactamase in imidazole/MPD 2 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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4ZDX
 | | Structure of OXA-51 beta-lactamase | | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Beta-lactamase, GLYCEROL | | 著者 | Smith, C.A, Antunes, N.T, Stewart, N.K, Frase, H, Toth, M, Kantardjieff, K.A, Vakulenko, S.B. | | 登録日 | 2015-04-20 | | 公開日 | 2015-06-17 | | 最終更新日 | 2015-09-02 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D beta-Lactamases.
Acs Chem.Biol., 10, 2015
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3LEZ
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