4ZDX

Structure of OXA-51 beta-lactamase

Summary for 4ZDX

• Entry DOI: 10.2210/pdb4zdx/pdb
• Descriptor: Beta-lactamase, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, GLYCEROL, ... (4 entities in total)
• Functional Keywords: antibiotic resistance, beta-lactamase, carbapenemase, mutant, hydrolase
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 1
• Total formula weight: 30958.40

Authors

Smith, C.A.,Antunes, N.T.,Stewart, N.K.,Frase, H.,Toth, M.,Kantardjieff, K.A.,Vakulenko, S.B. (deposition date: 2015-04-20, release date: 2015-06-17, Last modification date: 2015-09-02)

• Primary citation: Smith, C.A.,Antunes, N.T.,Stewart, N.K.,Frase, H.,Toth, M.,Kantardjieff, K.A.,Vakulenko, S.; Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D beta-Lactamases.; Acs Chem.Biol., 10:1791-1796, 2015; PubMed: 26042471; DOI: 10.1021/acschembio.5b00090

Experimental method

X-RAY DIFFRACTION (2.001 Å)