7MEB
CDD-1 beta-lactamase in imidazole/MPD 2 minute avibactam complex
Summary for 7MEB
Entry DOI | 10.2210/pdb7meb/pdb |
Related | 7LNO 7LNQ 7LNR |
Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, CARBON DIOXIDE, ... (6 entities in total) |
Functional Keywords | gram-positive, beta-lactamase, antibiotic resistance, inhibitor, avibactam, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Clostridioides difficile (Peptoclostridium difficile) |
Total number of polymer chains | 1 |
Total formula weight | 29526.99 |
Authors | |
Primary citation | Stewart, N.K.,Toth, M.,Stasyuk, A.,Vakulenko, S.B.,Smith, C.A. In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases. Acs Infect Dis., 7:1765-1776, 2021 Cited by PubMed: 33908775DOI: 10.1021/acsinfecdis.1c00094 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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