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2RUK
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BU of 2ruk by Molmil
Solution structure of the complex between p53 transactivation domain 2 and TFIIH p62 PH domain
分子名称: Cellular tumor antigen p53, General transcription factor IIH subunit 1
著者Okuda, M, Nishimura, Y.
登録日2014-09-24
公開日2014-10-15
最終更新日2022-08-24
実験手法SOLUTION NMR
主引用文献Extended string binding mode of the phosphorylated transactivation domain of tumor suppressor p53.
J.Am.Chem.Soc., 136, 2014
2RVN
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BU of 2rvn by Molmil
Solution structure of the chromodomain of HP1a with the phosphorylated N-terminal tail complexed with H3K9me3 peptide
分子名称: 18-mer peptide of Histone H3, Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2RVL
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BU of 2rvl by Molmil
Solution structure of the chromodomain of HP1alpha with the N-terminal tail
分子名称: Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2Z33
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BU of 2z33 by Molmil
Solution structure of the DNA complex of PhoB DNA-binding/transactivation Domain
分子名称: 5'-D(*AP*CP*AP*GP*AP*TP*TP*TP*AP*TP*GP*AP*CP*AP*GP*T)-3', 5'-D(*AP*CP*TP*GP*TP*CP*AP*TP*AP*AP*AP*TP*CP*TP*GP*T)-3', Phosphate regulon transcriptional regulatory protein phoB
著者Yamane, T, Okamura, H, Ikeguchi, M, Nishimura, Y, Kidera, A.
登録日2007-05-31
公開日2008-04-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Water-mediated interactions between DNA and PhoB DNA-binding/transactivation domain: NMR-restrained molecular dynamics in explicit water environment.
Proteins, 71, 2008
1ITY
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BU of 1ity by Molmil
Solution structure of the DNA binding domain of human TRF1
分子名称: TRF1
著者Nishikawa, T, Okamura, H, Nagadoi, A, Konig, P, Rhodes, D, Nishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-02-15
公開日2002-03-06
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a telomeric DNA complex of human TRF1
Structure, 9, 2001
1J05
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BU of 1j05 by Molmil
The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
分子名称: GLYCEROL, PHOSPHATE ION, anti-CEA mAb T84.66, ...
著者Kondo, H, Nishimura, Y, Shiroishi, M, Asano, R, Noro, N, Tsumoto, K, Kumagai, I.
登録日2002-11-01
公開日2003-12-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
To be Published
1IV6
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BU of 1iv6 by Molmil
Solution Structure of the DNA Complex of Human TRF1
分子名称: 5'-D(*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*C)-3', 5'-D(*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3', TELOMERIC REPEAT BINDING FACTOR 1
著者Nishikawa, T, Okamura, H, Nagadoi, A, Konig, P, Rhodes, D, Nishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-14
公開日2002-04-17
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a telomeric DNA complex of human TRF1.
Structure, 9, 2001
7BWI
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BU of 7bwi by Molmil
Solution structure of recombinant APETx1
分子名称: Kappa-actitoxin-Ael2a
著者Matsumura, K, Kobayashi, N, Kurita, J, Nishimura, Y, Yokogawa, M, Imai, S, Shimada, I, Osawa, M.
登録日2020-04-14
公開日2020-12-23
最終更新日2021-07-14
実験手法SOLUTION NMR
主引用文献Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization.
Bmc Mol Cell Biol, 22, 2021
2DY7
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BU of 2dy7 by Molmil
Solution structure of the first chromodomain of yeast Chd1
分子名称: Chromo domain protein 1
著者Okuda, M, Nishimura, Y.
登録日2006-09-07
公開日2006-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Polymorphism of Chromodomains in Chd1
J.Mol.Biol., 365, 2007
7DTI
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BU of 7dti by Molmil
Solution structure of the complex between RNA polymerase subunit RPB6 and TFIIH p62 PH domain
分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC2, ...
著者Okuda, M, Nishimura, Y.
登録日2021-01-05
公開日2022-08-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Three human RNA polymerases interact with TFIIH via a common RPB6 subunit.
Nucleic Acids Res., 50, 2022
7DTH
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BU of 7dth by Molmil
Solution structure of RPB6, common subunit of RNA polymerases I, II, and III
分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC2
著者Okuda, M, Nishimura, Y.
登録日2021-01-05
公開日2022-01-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Three human RNA polymerases interact with TFIIH via a common RPB6 subunit.
Nucleic Acids Res., 50, 2022
2CZY
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BU of 2czy by Molmil
Solution structure of the NRSF/REST-mSin3B PAH1 complex
分子名称: Paired amphipathic helix protein Sin3b, transcription factor REST (version 3)
著者Nomura, M, Uda-Tochio, H, Murai, K, Mori, N, Nishimura, Y.
登録日2005-07-20
公開日2005-12-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Neural Repressor NRSF/REST Binds the PAH1 Domain of the Sin3 Corepressor by Using its Distinct Short Hydrophobic Helix
J.Mol.Biol., 354, 2005
2DY8
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BU of 2dy8 by Molmil
Solution structure of the second chromodomain of yeast Chd1
分子名称: Chromo domain protein 1
著者Okuda, M, Nishimura, Y.
登録日2006-09-07
公開日2006-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Polymorphism of Chromodomains in Chd1
J.Mol.Biol., 365, 2007
3APN
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BU of 3apn by Molmil
Crystal structure of the human wild-type PAD4 protein
分子名称: Protein-arginine deiminase type-4
著者Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H.
登録日2010-10-19
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene
Acta Crystallogr.,Sect.D, 67, 2011
3APM
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BU of 3apm by Molmil
Crystal structure of the human SNP PAD4 protein
分子名称: Protein-arginine deiminase type-4
著者Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H.
登録日2010-10-19
公開日2011-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene
Acta Crystallogr.,Sect.D, 67, 2011
6K5W
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BU of 6k5w by Molmil
Solution structure of the chromodomain of yeast Eaf3
分子名称: Chromatin modification-related protein EAF3
著者Okuda, M, Nishimura, Y.
登録日2019-05-31
公開日2020-02-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Eaf3 chromodomain acts as a pH sensor for gene expression by altering its binding affinity for histone methylated-lysine residues.
Biosci.Rep., 40, 2020
7BUL
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BU of 7bul by Molmil
Solution structure of the tandem PH and BSD1 domains of TFIIH p62
分子名称: General transcription factor IIH subunit 1
著者Okuda, M, Nishimura, Y.
登録日2020-04-07
公開日2020-12-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and dynamical insights into the PH domain of p62 in human TFIIH.
Nucleic Acids Res., 49, 2021
1JI2
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BU of 1ji2 by Molmil
Improved X-ray Structure of Thermoactinomyces vulgaris R-47 alpha-Amylase 2
分子名称: ALPHA-AMYLASE II, CALCIUM ION
著者Kamitori, S, Abe, A, Ohtaki, A, Kaji, A, Tonozuka, T, Sakano, Y.
登録日2001-06-28
公開日2002-06-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures and structural comparison of Thermoactinomyces vulgaris R-47 alpha-amylase 1 (TVAI) at 1.6 A resolution and alpha-amylase 2 (TVAII) at 2.3 A resolution.
J.Mol.Biol., 318, 2002
6WAU
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BU of 6wau by Molmil
Complex structure of PHF19
分子名称: Histone H3.1t peptide, PHD finger protein 19, UNKNOWN ATOM OR ION
著者Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC)
登録日2020-03-26
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
Elife, 9, 2020
6WAV
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BU of 6wav by Molmil
Crystal structure of PHF1 in complex with H3K36me3 substitution
分子名称: Histone H3.1, PHD finger protein 1, SULFATE ION, ...
著者Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC)
登録日2020-03-26
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
Elife, 9, 2020
6WAT
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BU of 6wat by Molmil
complex structure of PHF1
分子名称: Histone H3.1t peptide, PHD finger protein 1, UNKNOWN ATOM OR ION
著者Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC)
登録日2020-03-26
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19.
Elife, 9, 2020
1ODD
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BU of 1odd by Molmil
OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI
分子名称: TRANSCRIPTIONAL REGULATORY PROTEIN OMPR
著者Kondou, H, Nakagawa, A, Tanaka, I.
登録日1996-10-31
公開日1997-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.
Nat.Struct.Biol., 4, 1997
1IDZ
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BU of 1idz by Molmil
STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, 20 STRUCTURES
分子名称: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
著者Furukawa, K, Oda, M, Nakamura, H.
登録日1996-08-15
公開日1996-12-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Proc.Natl.Acad.Sci.USA, 93, 1996
1IDY
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BU of 1idy by Molmil
STRUCTURE OF MYB TRANSFORMING PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
著者Furukawa, K, Oda, M, Nakamura, H.
登録日1996-08-15
公開日1996-12-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.
Proc.Natl.Acad.Sci.USA, 93, 1996
7YV1
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BU of 7yv1 by Molmil
Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ...
著者Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A.
登録日2022-08-18
公開日2023-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.454 Å)
主引用文献Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
J.Am.Chem.Soc., 145, 2023

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