6YE8
 
 | | E.coli's Putrescine receptor PotF complexed with Spermidine | | 分子名称: | (2R)-1-methoxypropan-2-amine, (2~{S})-1-(2-methoxyethoxy)propan-2-amine, CHLORIDE ION, ... | | 著者 | Shanmugaratnam, S, Kroeger, P, Hocker, B. | | 登録日 | 2020-03-24 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
Structure, 29, 2021
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6YEB
 | | E.coli's Putrescine receptor PotF in its closed apo state | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Shanmugaratnam, S, Kroeger, P, Hocker, B. | | 登録日 | 2020-03-24 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
Structure, 29, 2021
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6YE7
 | | E.coli's Putrescine receptor PotF complexed with Cadaverine | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... | | 著者 | Shanmugaratnam, S, Kroeger, P, Hocker, B. | | 登録日 | 2020-03-24 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
Structure, 29, 2021
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6YE0
 | | E.coli's Putrescine receptor PotF complexed with Putrescine | | 分子名称: | (2R)-1-methoxypropan-2-amine, (2~{R})-1-[(2~{R})-1-(2-methoxyethoxy)propan-2-yl]oxypropan-2-amine, (2~{S})-1-(2-methoxyethoxy)propan-2-amine, ... | | 著者 | Shanmugaratnam, S, Kroeger, P, Hocker, B. | | 登録日 | 2020-03-23 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
Structure, 29, 2021
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6YEC
 | | E.coli's Putrescine receptor PotF complexed with Spermine | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Shanmugaratnam, S, Kroeger, P, Hocker, B. | | 登録日 | 2020-03-24 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
Structure, 29, 2021
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7A8S
 | | de novo designed ba8-barrel sTIM11 with an alpha-helical extension | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, sTIM11_h3 | | 著者 | Shanmugaratnam, S, Wiese, J.G, Hocker, B. | | 登録日 | 2020-08-31 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Extension of a de novo TIM barrel with a rationally designed secondary structure element.
Protein Sci., 30, 2021
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8EXX
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA and foscarnet (pre-translocation state) | | 分子名称: | DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... | | 著者 | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | 登録日 | 2022-10-26 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Cell, 2024
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8V1R
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA and DTTP in closed conformation | | 分子名称: | DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... | | 著者 | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | 登録日 | 2023-11-21 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Cell, 2024
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8V1Q
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA in both open/closed conformations | | 分子名称: | DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... | | 著者 | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | 登録日 | 2023-11-21 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Cell, 2024
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8V1S
 | | Herpes simplex virus 1 polymerase holoenzyme bound to mismatched DNA in editing conformation | | 分子名称: | DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... | | 著者 | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | 登録日 | 2023-11-21 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Cell, 2024
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8V1T
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA and acyclovir triphosphate in closed conformation | | 分子名称: | ACYCLOVIR TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | | 著者 | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | 登録日 | 2023-11-21 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Cell, 2024
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7WHU
 | | Human Neutrophil Elastase in-complex with Ecotin Peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ecotin Peptide, ... | | 著者 | Shankar, S, Jayaraman, S. | | 登録日 | 2021-12-31 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Sequence preference and scaffolding requirement for the inhibition of human neutrophil elastase by ecotin peptide
Protein Sci., 31, 2022
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2XXA
 | | The Crystal Structure of the Signal Recognition Particle (SRP) in Complex with its Receptor(SR) | | 分子名称: | 4.5S RNA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Ataide, S.F, Schmitz, N, Shen, K, Ke, A, Shan, S, Doudna, J.A, Ban, N. | | 登録日 | 2010-11-09 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.94 Å) | | 主引用文献 | The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Science, 331, 2011
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5AKA
 | | EM structure of ribosome-SRP-FtsY complex in closed state | | 分子名称: | 23S ribosomal RNA, 4.5S ribosomal RNA, 50S RIBOSOMAL PROTEIN L11, ... | | 著者 | von Loeffelholz, O, Jiang, Q, Ariosa, A, Karuppasamy, M, Huard, K, Berger, I, Shan, S, Schaffitzel, C. | | 登録日 | 2015-03-03 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Ribosome-Srp-Ftsy Cotranslational Targeting Complex in the Closed State.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6AE8
 | | Structure insight into histone chaperone Chz1-mediated H2A.Z recognition and replacement | | 分子名称: | BICINE, Histone H2A.Z-specific chaperone CHZ1, Histone H2B.1,Histone H2A.Z | | 著者 | Wang, Y.Y, Shan, S, Zhou, Z. | | 登録日 | 2018-08-03 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insights into histone chaperone Chz1-mediated H2A.Z recognition and histone replacement.
Plos Biol., 17, 2019
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5Z78
 | | Structure of TIRR/53BP1 complex | | 分子名称: | TP53-binding protein 1, Tudor-interacting repair regulator protein | | 著者 | Dai, Y.X, Shan, S. | | 登録日 | 2018-01-27 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | | 主引用文献 | Structural basis for recognition of 53BP1 tandem Tudor domain by TIRR
Nat Commun, 9, 2018
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6M0J
 | | Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | | 著者 | Wang, X, Lan, J, Ge, J, Yu, J, Shan, S. | | 登録日 | 2020-02-21 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor.
Nature, 581, 2020
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7D5Z
 | | Crystal structure of EBV gH/gL bound with neutralizing antibody 1D8 | | 分子名称: | Envelope glycoprotein H, Envelope glycoprotein L, heavy chain of 1D8, ... | | 著者 | Zhu, Q, Shan, S, Yu, J, Wang, X, Zhang, L, Zeng, M. | | 登録日 | 2020-09-28 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | A Neutralizing Antibody Targeting a New Site of Vulnerability on Epstein-Barr Virus gH/gL Protects against Dual-Tropic Infection
To Be Published
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7WLP
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6FAL
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6F7F
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6F7G
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6F9K
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4V6I
 | | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... | | 著者 | Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | 登録日 | 2010-10-12 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | | 主引用文献 | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7E
 | | Model of the small subunit RNA based on a 5.5 A cryo-EM map of Triticum aestivum translating 80S ribosome | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S10E, ... | | 著者 | Barrio-Garcia, C, Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | 登録日 | 2013-11-22 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion.
Nature, 506, 2014
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