5ZO9
 
 | | Eg5 motor domain in complex with STLC-type inhibitor PVEI0021 (C2 type) | | 分子名称: | (2R)-2-azanyl-3-[(4-methoxyphenyl)-diphenyl-methyl]sulfanyl-propanoic acid, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | | 著者 | Yokoyama, H, Sato, K. | | 登録日 | 2018-04-12 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors.
Acs Omega, 3, 2018
|
|
5ZO8
 | |
5ZO7
 | | Kinesin spindle protein Eg5 in complex with STLC-type inhibitor PVEI0138 | | 分子名称: | (2R)-2-azanyl-3-[[2-(4-methoxyphenyl)-2-tricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaenyl]sulfanyl]propanoic acid, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | | 著者 | Yokoyama, H, Sato, K. | | 登録日 | 2018-04-12 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors.
Acs Omega, 3, 2018
|
|
1V5A
 | |
1D1H
 | | SOLUTION STRUCTURE OF HANATOXIN 1 | | 分子名称: | HANATOXIN TYPE 1 | | 著者 | Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I. | | 登録日 | 1999-09-16 | | 公開日 | 2000-09-20 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.
J.Mol.Biol., 297, 2000
|
|
6K4J
 | | Crystal Structure of the the CD9 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CD9 antigen, NICKEL (II) ION, ... | | 著者 | Umeda, R, Nishizawa, T, Sato, K, Nureki, O. | | 登録日 | 2019-05-24 | | 公開日 | 2020-05-13 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Structural insights into tetraspanin CD9 function.
Nat Commun, 11, 2020
|
|
1KEG
 | | Antibody 64M-2 Fab complexed with dTT(6-4)TT | | 分子名称: | 5'-D(*TP*(64T)P*TP*T)-3', Anti-(6-4) photoproduct antibody 64M-2 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-2 Fab (light chain), ... | | 著者 | Yokoyama, H, Mizutani, R, Satow, Y, Sato, K, Komatsu, Y, Ohtsuka, E, Nikaido, O. | | 登録日 | 2001-11-15 | | 公開日 | 2002-11-15 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the DNA (6-4) photoproduct dTT(6-4)TT in complex with the 64M-2 antibody Fab fragment implies increased antibody-binding affinity by the flanking nucleotides.
Acta Crystallogr.,Sect.D, 68, 2012
|
|
3WMD
 | | Crystal structure of epoxide hydrolase MonBI | | 分子名称: | Probable monensin biosynthesis isomerase | | 著者 | Minami, A, Ose, T, Sato, K, Oikawa, A, Kuroki, K, Maenaka, K, Oguri, H, Oikawa, H. | | 登録日 | 2013-11-16 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Allosteric regulation of epoxide opening cascades by a pair of epoxide hydrolases in monensin biosynthesis
Acs Chem.Biol., 9, 2014
|
|
6JOU
 | | Crystal structure of the human nucleosome containing H2A.Z.1 S42R | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | | 著者 | Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H. | | 登録日 | 2019-03-23 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo.
Biochem.Biophys.Res.Commun., 515, 2019
|
|
3WA9
 | | The nucleosome containing human H2A.Z.1 | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | | 著者 | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | | 登録日 | 2013-04-30 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2
Acta Crystallogr.,Sect.D, 69, 2013
|
|
3WAA
 | | The nucleosome containing human H2A.Z.2 | | 分子名称: | DNA (146-MER), Histone H2A.V, Histone H2B type 1-J, ... | | 著者 | Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H. | | 登録日 | 2013-04-30 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2
Acta Crystallogr.,Sect.D, 69, 2013
|
|
2E42
 | | Crystal structure of C/EBPbeta Bzip homodimer V285A mutant bound to A High Affinity DNA fragment | | 分子名称: | CCAAT/enhancer-binding protein beta, DNA (5'-D(P*DAP*DAP*DTP*DAP*DTP*DTP*DGP*DCP*DGP*DCP*DAP*DAP*DTP*DCP*DCP*DT)-3'), DNA (5'-D(P*DTP*DAP*DGP*DGP*DAP*DTP*DTP*DGP*DCP*DGP*DCP*DAP*DAP*DTP*DAP*DT)-3') | | 著者 | Tahirov, T.H, Inoue-Bungo, T, Sato, K, Shiina, M, Hamada, K, Ogata, K. | | 登録日 | 2006-12-01 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Basis for Flexible Base Recognition by C/Ebpbeta
To be Published
|
|
2E43
 | | Crystal structure of C/EBPbeta Bzip homodimer K269A mutant bound to A High Affinity DNA fragment | | 分子名称: | CCAAT/enhancer-binding protein beta, DNA (5'-D(P*DAP*DAP*DTP*DAP*DTP*DTP*DGP*DCP*DGP*DCP*DAP*DAP*DTP*DCP*DCP*DT)-3'), DNA (5'-D(P*DTP*DAP*DGP*DGP*DAP*DTP*DTP*DGP*DCP*DGP*DCP*DAP*DAP*DTP*DAP*DT)-3') | | 著者 | Tahirov, T.H, Inoue-Bungo, T, Sato, K, Shiina, M, Hamada, K, Ogata, K. | | 登録日 | 2006-12-01 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Flexible Base Recognition by C/Ebpbeta
To be Published
|
|
2DI2
 | | NMR structure of the HIV-2 nucleocapsid protein | | 分子名称: | Nucleocapsid protein p7, ZINC ION | | 著者 | Matsui, T, Kodera, Y, Endoh, H, Miyauchi, E, Komatsu, H, Sato, K, Tanaka, T, Kohno, T, Maeda, T. | | 登録日 | 2006-03-27 | | 公開日 | 2007-03-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | RNA Recognition Mechanism of the Minimal Active Domain of the Human Immunodeficiency Virus Type-2 Nucleocapsid Protein
J.Biochem.(Tokyo), 141, 2007
|
|
2XV3
 | | Pseudomonas aeruginosa Azurin with mutated metal-binding loop sequence (CAAAAHAAAAM), chemically reduced, pH5.3 | | 分子名称: | AZURIN, COPPER (I) ION | | 著者 | Li, C, Sato, K, Monari, S, Salard, I, Sola, M, Banfield, M.J, Dennison, C. | | 登録日 | 2010-10-22 | | 公開日 | 2010-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Metal-Binding Loop Length is a Determinant of the Pka of a Histidine Ligand at a Type 1 Copper Site
Inorg.Chem., 50, 2011
|
|
2XV2
 | | Pseudomonas aeruginosa Azurin with mutated metal-binding loop sequence (CAAHAAM), chemically reduced, pH4.2 | | 分子名称: | AZURIN, COPPER (I) ION | | 著者 | Li, C, Sato, K, Monari, S, Salard, I, Sola, M, Banfield, M.J, Dennison, C. | | 登録日 | 2010-10-22 | | 公開日 | 2010-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Metal-Binding Loop Length is a Determinant of the Pka of a Histidine Ligand at a Type 1 Copper Site
Inorg.Chem., 50, 2011
|
|
7L1X
 | | Structure of human CK2 alpha kinase (catalytic subunit) with the inhibitor 108600. | | 分子名称: | (2~{Z})-6-[[2,6-bis(chloranyl)phenyl]methylsulfonyl]-2-[[4-oxidanyl-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]methylidene]-4~{H}-1,4-benzothiazin-3-one, Casein kinase II subunit alpha, GLYCEROL, ... | | 著者 | Rechkoblit, O, Aggarwal, A.K. | | 登録日 | 2020-12-15 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease.
Nat Commun, 12, 2021
|
|
3FT0
 | |
3FSW
 | |
3FSZ
 | |
3FSA
 | |
3FS9
 | |
3FSV
 | |
3UFI
 | |
6WNK
 | | Macrocyclic peptides TDI5575 that selectively inhibit the Mycobacterium tuberculosis proteasome | | 分子名称: | (12S,15S)-N-[(2-fluorophenyl)methyl]-10,13-dioxo-12-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}-2-oxa-11,14-diazatricyclo[15.2.2.1~3,7~]docosa-1(19),3(22),4,6,17,20-hexaene-15-carboxamide, CITRIC ACID, DIMETHYLFORMAMIDE, ... | | 著者 | Hsu, H.C, Li, H. | | 登録日 | 2020-04-22 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.
J.Med.Chem., 64, 2021
|
|
