7DTT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dtt by Molmil](/molmil-images/mine/7dtt) | Human Calcium-Sensing Receptor bound with calcium ions | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ling, S.L, Tian, C.L, Shi, P, Liu, S.L, Meng, X.Y, Sun, D.M, Liu, L, Shi, C.W. | 登録日 | 2021-01-06 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31, 2021
|
|
7DTV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dtv by Molmil](/molmil-images/mine/7dtv) | Human Calcium-Sensing Receptor bound with L-Trp and calcium ions | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ling, S.L, Tian, C.L, Shi, P, Liu, S.L, Meng, X.Y, Liu, L, Sun, D.M, Shi, C.W. | 登録日 | 2021-01-06 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31, 2021
|
|
3F62
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f62 by Molmil](/molmil-images/mine/3f62) | |
4ZO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zo5 by Molmil](/molmil-images/mine/4zo5) | PDE10 complexed with 4-isopropoxy-2-(2-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione | 分子名称: | 2-{2-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}-4-(propan-2-yloxy)-1H-isoindole-1,3(2H)-dione, 3-(1-hydroxy-2-methylpropan-2-yl)-5-phenyl-3,5-dihydro-1H-imidazo[4,5-c][1,8]naphthyridine-2,4-dione, MAGNESIUM ION, ... | 著者 | Yan, Y. | 登録日 | 2015-05-06 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of [(11)C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
|
|
5GQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gqh by Molmil](/molmil-images/mine/5gqh) | Cryo-EM structure of PaeCas3-AcrF3 complex | 分子名称: | CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3 | 著者 | Zhang, X, Ma, J, Wang, Y, Wang, J. | 登録日 | 2016-08-07 | 公開日 | 2016-09-21 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses Cell Res., 26, 2016
|
|
3J3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j3y by Molmil](/molmil-images/mine/3j3y) | |
7JRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jrn by Molmil](/molmil-images/mine/7jrn) | Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617 | 分子名称: | 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ... | 著者 | Sacco, M, Ma, C, Wang, J, Chen, Y. | 登録日 | 2020-08-12 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay. Acs Cent.Sci., 7, 2021
|
|
5GNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gnf by Molmil](/molmil-images/mine/5gnf) | |
7KSP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ksp by Molmil](/molmil-images/mine/7ksp) | Crystal structure of hSAMD9_DBD with DNA | 分子名称: | DNA, Sterile alpha motif domain-containing protein 9 | 著者 | Peng, S, Pathak, P, Xiang, Y, Deng, J. | 登録日 | 2020-11-23 | 公開日 | 2022-01-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7LYI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lyi by Molmil](/molmil-images/mine/7lyi) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-3 | 分子名称: | 3C-like proteinase, GLYCEROL, SODIUM ION, ... | 著者 | Sacco, M, Wang, J, Chen, Y. | 登録日 | 2021-03-07 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir. Acs Pharmacol Transl Sci, 4, 2021
|
|
7LYH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lyh by Molmil](/molmil-images/mine/7lyh) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-1 | 分子名称: | 3C-like proteinase, GLYCEROL, benzyl (1S,3aR,6aS)-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamoyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate | 著者 | Sacco, M, Wang, J, Chen, Y. | 登録日 | 2021-03-07 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir. Acs Pharmacol Transl Sci, 4, 2021
|
|
6U8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u8y by Molmil](/molmil-images/mine/6u8y) | |
6KYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kyf by Molmil](/molmil-images/mine/6kyf) | Crystal structure of an anti-CRISPR protein | 分子名称: | AcrF11, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Niu, Y, Wang, H, Zhang, Y, Feng, Y. | 登録日 | 2019-09-18 | 公開日 | 2020-09-23 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | A Type I-F Anti-CRISPR Protein Inhibits the CRISPR-Cas Surveillance Complex by ADP-Ribosylation. Mol.Cell, 80, 2020
|
|
5YGI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ygi by Molmil](/molmil-images/mine/5ygi) | |
2KOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kod by Molmil](/molmil-images/mine/2kod) | A high-resolution NMR structure of the dimeric C-terminal domain of HIV-1 CA | 分子名称: | HIV-1 CA C-terminal domain | 著者 | Byeon, I.-J.L, Jung, J, Ahn, J, concel, J, Gronenborn, A.M. | 登録日 | 2009-09-18 | 公開日 | 2009-11-24 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell(Cambridge,Mass.), 139, 2009
|
|
7VRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vrd by Molmil](/molmil-images/mine/7vrd) | |
7V67
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v67 by Molmil](/molmil-images/mine/7v67) | |
7FB8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fb8 by Molmil](/molmil-images/mine/7fb8) | De Novo-Designed and Disulfide-Bridged Peptide Heterodimer - hd1 | 分子名称: | ASP-ASP-LYS-ASP-CYS-ASP-GLU-TYR-CYS-LYS-LYS-THR-LYS-GLU-NH2, GLU-LE1-THR-GLY-HIS-ILE-GLU-GLY-PRO-THR-LE1-THR-LE1-HIS-CYS-LYS-NH2 | 著者 | Yao, H, Yao, S, Zheng, Y, Moyer, A, Baker, D, Wu, C. | 登録日 | 2021-07-08 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design and directed folding of disulfide-bridged peptide heterodimers. Nat Commun, 13, 2022
|
|
7FBA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7fba by Molmil](/molmil-images/mine/7fba) | De Novo-Designed and Disulfide-Bridged Peptide Heterodimer - hd2 | 分子名称: | ALA-LE1-CYS-GLU-CYS-GLY-PRO-THR-ARG-GLU-CYS-LYS-NH2, GLU-CYS-ARG-GLU-TYR-GLY-PRO-LE1-LYS-LE1-LE1-ALA-NH2 | 著者 | Yao, H, Yao, S, Moyer, A, Zheng, Y, Baker, D, Wu, C. | 登録日 | 2021-07-08 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design and directed folding of disulfide-bridged peptide heterodimers. Nat Commun, 13, 2022
|
|
3KEA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kea by Molmil](/molmil-images/mine/3kea) | |
5EOQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eoq by Molmil](/molmil-images/mine/5eoq) | |
3J3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3j3q by Molmil](/molmil-images/mine/3j3q) | |
5EOR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5eor by Molmil](/molmil-images/mine/5eor) | |
4EKX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ekx by Molmil](/molmil-images/mine/4ekx) | |
4ETQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4etq by Molmil](/molmil-images/mine/4etq) | |