3KBA
| Progesterone receptor bound to sulfonamide pyrrolidine partial agonist | 分子名称: | 2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfonyl)pyrrolidin-3-yl]amino}benzonitrile, Progesterone receptor, SULFATE ION | 著者 | Kallander, L.S, Washburn, D.G, Williams, S.P, Madauss, K.P. | 登録日 | 2009-10-20 | 公開日 | 2009-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Improving the developability profile of pyrrolidine progesterone receptor partial agonists. Bioorg.Med.Chem.Lett., 20, 2010
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8DGG
| Structure of glycosylated LAG-3 homodimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Silberstein, J.L, Mathews, I.I, Frank, J.A, Chan, K.-W, Fernandez, D, Du, J, Wang, J, Kong, X.-P, Cochran, J.R. | 登録日 | 2022-06-23 | 公開日 | 2022-08-17 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (3.78 Å) | 主引用文献 | Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function. Proc.Natl.Acad.Sci.USA, 121, 2024
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7E3J
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3PZD
| Structure of the myosin X MyTH4-FERM/DCC complex | 分子名称: | GLYCEROL, Myosin-X, Netrin receptor DCC | 著者 | Wei, Z, Yan, J, Pan, L, Zhang, M. | 登録日 | 2010-12-14 | 公開日 | 2011-02-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain Proc.Natl.Acad.Sci.USA, 108, 2011
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4FMB
| VirA-Rab1 complex structure | 分子名称: | ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Shao, F, Zhu, Y. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2012-10-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMA
| EspG structure | 分子名称: | ACETIC ACID, EspG protein, FORMIC ACID, ... | 著者 | Shao, F, Zhu, Y, Hu, L. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FME
| EspG-Rab1-Arf6 complex | 分子名称: | ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ... | 著者 | Shao, F, Zhu, Y. | 登録日 | 2012-06-16 | 公開日 | 2012-09-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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5X0S
| Solution NMR structure of peptide toxin SsTx from Scolopendra subspinipes mutilans | 分子名称: | SsTx | 著者 | Wu, F, Luo, L, Qu, D, Zhang, L, Tian, C, Lai, R. | 登録日 | 2017-01-23 | 公開日 | 2018-01-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Centipedes subdue giant prey by blocking KCNQ channels Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7KH0
| Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex | 分子名称: | Arg-vasopressin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, L, Xu, J, Gao, S, Sun, D, Liu, H, Liu, Z, Du, Y, Zhang, C. | 登録日 | 2020-10-19 | 公開日 | 2021-05-26 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex. Cell Res., 31, 2021
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4JNC
| Soluble Epoxide Hydrolase complexed with a carboxamide inhibitor | 分子名称: | 1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[2-(trifluoromethyl)benzyl]piperidine-4-carboxamide, Bifunctional epoxide hydrolase 2 | 著者 | Shewchuk, L.M. | 登録日 | 2013-03-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase. Bioorg.Med.Chem.Lett., 23, 2013
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6LON
| Crystal structure of HPSG | 分子名称: | (2~{S})-2,3-bis(oxidanyl)propane-1-sulfonic acid, GLYCEROL, PFL2/glycerol dehydratase family glycyl radical enzyme, ... | 著者 | Liu, J, Zhang, Y, Yuchi, Z. | 登録日 | 2020-01-06 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Two radical-dependent mechanisms for anaerobic degradation of the globally abundant organosulfur compound dihydroxypropanesulfonate. Proc.Natl.Acad.Sci.USA, 117, 2020
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5ET0
| Crystal structure of Myo3b-ARB2 in complex with Espin1-AR | 分子名称: | Espin, Myosin-IIIb | 著者 | Liu, H, Li, J, Liu, W, Zhang, M. | 登録日 | 2015-11-17 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin Elife, 5, 2016
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5ET1
| Crystal structure of Myo3b-ARB1 in complex with Espin1-AR | 分子名称: | Espin, GLYCEROL, Myosin-IIIb | 著者 | Liu, H, Li, J, liu, W, Zhang, M. | 登録日 | 2015-11-17 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin Elife, 5, 2016
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5EXH
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6N29
| Crystal structure of monomeric von Willebrand Factor D`D3 assembly | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Dong, X, Arndt, J.W, Springer, T.A. | 登録日 | 2018-11-12 | 公開日 | 2019-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis. Blood, 133, 2019
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8WFX
| Cryo-EM structure of CRISPR-Csm effector complex from Mycobacterium canettii | 分子名称: | CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ... | 著者 | Huo, Y, Ma, X, Jiang, T. | 登録日 | 2023-09-20 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Type-III-A structure of mycobacteria CRISPR-Csm complexes involving atypical crRNAs. Int.J.Biol.Macromol., 260, 2024
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7VH0
| MT2-remalteon-Gi complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Melatonin receptor type 1B, ... | 著者 | Wang, Q.G, Lu, Q.Y. | 登録日 | 2021-09-20 | 公開日 | 2022-03-02 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
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7VGY
| Melatonin receptor1-2-Iodomelatonin-Gicomplex | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, Q.G, Lu, Q.Y. | 登録日 | 2021-09-20 | 公開日 | 2022-03-02 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
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7VGZ
| MT1-remalteon-Gi complex | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, Q.G, Lu, Q.Y. | 登録日 | 2021-09-20 | 公開日 | 2022-03-02 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of the ligand binding and signaling mechanism of melatonin receptors. Nat Commun, 13, 2022
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6A7W
| Structure of a catalytic domain of the colistin resistance enzyme | 分子名称: | Putative integral membrane protein, ZINC ION | 著者 | Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F. | 登録日 | 2018-07-04 | 公開日 | 2018-11-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | 主引用文献 | Structural and functional insights into MCR-2 mediated colistin resistance. Sci China Life Sci, 61, 2018
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6B40
| BbRAGL-3'TIR synaptic complex with nicked DNA refined with C2 symmetry | 分子名称: | 31TIR intact strand, 31TIR pre-nicked strand of flanking DNA, 31TIR pre-nicked strand of signal DNA, ... | 著者 | Zhang, Y, Cheng, T.C, Xiong, Y, Schatz, D.G. | 登録日 | 2017-09-25 | 公開日 | 2019-03-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Transposon molecular domestication and the evolution of the RAG recombinase. Nature, 569, 2019
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8X5D
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1S1G
| Crystal Structure of Kv4.3 T1 Domain | 分子名称: | Potassium voltage-gated channel subfamily D member 3, ZINC ION | 著者 | Scannevin, R.H, Wang, K.W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.X, Xu, Z.B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2004-03-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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1S1E
| Crystal Structure of Kv Channel-interacting protein 1 (KChIP-1) | 分子名称: | CALCIUM ION, Kv channel interacting protein 1 | 著者 | Scannevin, R.H, Wang, K.-W, Jow, F, Megules, J, Kopsco, D.C, Edris, W, Carroll, K.C, Lu, Q, Xu, W.-X, Xu, Z.-B, Katz, A.H, Olland, S, Lin, L, Taylor, M, Stahl, M, Malakian, K, Somers, W, Mosyak, L, Bowlby, M.R, Chanda, P, Rhodes, K.J. | 登録日 | 2004-01-06 | 公開日 | 2005-01-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Neuron, 41, 2004
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2HUR
| Escherichia coli nucleoside diphosphate kinase | 分子名称: | NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION | 著者 | Moynie, L, Giraud, M.-F, Georgescauld, F, Lascu, I, Dautant, A. | 登録日 | 2006-07-27 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family Proteins, 67, 2007
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