6DC1
| Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-nitro-2-oxidanyl-benzenecarbonitrile, ... | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
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7LOO
| S-adenosyl methionine transferase cocrystallized with ATP | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Jackson, C.J, Tan, L.L, Laurino, P. | 登録日 | 2021-02-10 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases. Jacs Au, 1, 2021
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6DNJ
| Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 28 round 5 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1,2-benzoxazole, Kemp eliminase KE07 | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | 登録日 | 2018-06-06 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
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6CT3
| Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 27 round 7-2 | 分子名称: | 5-nitro-2-oxidanyl-benzenecarbonitrile, GLYCEROL, Kemp eliminase, ... | 著者 | Jackson, C.J, Hong, N.-S, Carr, P.D. | 登録日 | 2018-03-22 | 公開日 | 2018-08-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
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6C8B
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6C7T
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6CAI
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4NP7
| Structure of phosphotriesterase mutant (S308L/Y309A) from Agrobacterium radiobacter with diethyl thiophosphate bound in the active site | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ... | 著者 | Jackson, C.J, Carr, P.D, Sugrue, E. | 登録日 | 2013-11-20 | 公開日 | 2014-09-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis Plos One, 9, 2014
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4PCN
| Phosphotriesterase variant R22 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R22, ZINC ION | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | 登録日 | 2014-04-16 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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4QQV
| Extracellular domains of mouse IL-3 beta receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-3 receptor class 2 subunit beta | 著者 | Jackson, C.J, Young, I.G, Murphy, J.M, Carr, P.D, Ewens, C.L, Dai, J, Ollis, D.L. | 登録日 | 2014-06-30 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Crystal structure of the mouse interleukin-3 beta-receptor: insights into interleukin-3 binding and receptor activation. Biochem.J., 463, 2014
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5D2Y
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5D2X
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5D2W
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5D38
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5D32
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5D2T
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5D37
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5D30
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5EHT
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5D2V
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5D33
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7K7U
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5IVH
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5JAB
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5BNC
| Structure of heme binding protein MSMEG_6519 from Mycobacterium smegmatis | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, NICKEL (II) ION, ... | 著者 | Ahmed, F.H, Carr, P.D, Jackson, C.J. | 登録日 | 2015-05-26 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria. J.Mol.Biol., 427, 2015
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